B8PWL7 (B8PWL7_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Disrupted in schizophrenia 1 EMBL ABY90095.1

Gene names

Name:

disc1 EMBL ABY90095.1 ZFIN ZDB-GENE-090122-1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL ABY90095.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	994 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological process	cartilage development involved in endochondral bone morphogenesis Inferred from mutant phenotype. Source: ZFIN embryonic cranial skeleton morphogenesis Inferred from mutant phenotype Ref.1. Source: ZFIN eurydendroid cell differentiation Inferred from mutant phenotype Ref.1. Source: ZFIN neural crest cell migration Inferred from mutant phenotype. Source: ZFIN oligodendrocyte cell fate specification Inferred from mutant phenotype Ref.1. Source: ZFIN
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8PWL7 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 9EEF266C7B6D96F6	FASTA	994	112,217
	10 20 30 40 50 60 MMFAGMVRVE NTSKTLKTDI DSPCHRCAVR TGGVNPSGNH RRRSFRRPGY MRSEPINQLD 70 80 90 100 110 120 VAETSCDSEH HRSPISKSPA VENTQKSASE LLGEKWLTEG FERDNSSKSS NKHHLHDEED 130 140 150 160 170 180 NLPVQSRDVF NSSFSFIQQS LDTSDLLDVN TCYSPRTEHK QSESASGHQL KSKTSNSGFL 190 200 210 220 230 240 KPPSDLMNHL SQSETSIVQM NQLETRTVPV SQSKSSFLKP LSALMNHLSQ SETTSVPINQ 250 260 270 280 290 300 SETSSAPKSQ SNSGFLKPLS DLMKHLTPPE SSIVLMNQSE TITIPMNQTK NSTIPVSQSN 310 320 330 340 350 360 ADFLNPPSAL MNHLNQSETV LIPMNQSETS SIPVSQSNSG FLKPSSNLIN HLSQSESVTV 370 380 390 400 410 420 PMNQSETSTV SLSQSEPDFF SLRHLPCSIG QSAQQKGLLL DRELWLVDLD LQTSSSIMSK 430 440 450 460 470 480 YTKENIQDSD SGSLDAEITS SHSIDSSDST SSGYESTTPS SDQSQDGLMK KYEDFLQDCL 490 500 510 520 530 540 QNNRTNTKIE SIMMKLQRLQ HKAILDDDYD TAERFGKKLE ELRRERATLK PGLPSRHPEV 550 560 570 580 590 600 TGYLERLRTA VNSAIHRTDS DCSTGDPSED QRSCISQSRA QTRETLLEEK QRIQKEMCDV 610 620 630 640 650 660 QRRLRDLQER SRALELQLEL QEMQGPVLRA ADSPHLHLTA RALEDLLTSE HRQRISVSPP 670 680 690 700 710 720 AHIRRLEEQE RVLSLSIREA ETKVLLNQRL CFSLRQKVSE SETQLLALHE AKLTAVSGND 730 740 750 760 770 780 FSSAKELKAE IRSVYRERDR LELLHRKLQT LSTGSGLDLS RMKEKHKHIK LELQNGEAQY 790 800 810 820 830 840 ERSLKENTVK YIELLEDKLH SCGSAALEHV LEADLEACHL LLKGLDQRNL SLSQTEDLPS 850 860 870 880 890 900 GSASASDVLQ FTKDEEDCAM LTALGGRWCP EADLQHSQFT KKLEEFLFCL EDEAPENLCG 910 920 930 940 950 960 ETTELTERCE LISYRLHYLE EQLQTAIDNN DKELTLSLER EVLELKSALQ AMLSQLKEED 970 980 990 EDEEDEEKYC DVEEEQVEDE DLEEEHYFSD SWEI

References

[1]	"Disrupted-in-schizophrenia 1 and neuregulin 1 are required for the specification of oligodendrocytes and neurones in the zebrafish brain." Wood J.D., Bonath F., Kumar S., Ross C.A., Cunliffe V.T. Hum. Mol. Genet. 18:391-404(2009) [PubMed: 18996920] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	EU273350 mRNA. Translation: ABY90095.1.
IPI	IPI00915619.
RefSeq	NP_001135735.1. NM_001142263.1.
UniGene	Dr.83248.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B8PWL7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	407621.
KEGG	dre:407621.
Organism-specific databases
CTD	27185.
ZFIN	ZDB-GENE-090122-1. disc1.
Phylogenomic databases
HOVERGEN	HBG106916.
OrthoDB	EOG4DNF3X.
Gene expression databases
Bgee	B8PWL7.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

B8PWL7_DANRE

Accession

Primary (citable) accession number: B8PWL7

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)