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B8NPL7 (BGLH_ASPFN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase H

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase H
Cellobiase H
Gentiobiase H
Gene names
Name:bglH
ORF Names:AFLA_000810
OrganismAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) [Complete proteome]
Taxonomic identifier332952 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length827 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Contains 1 PA14 domain.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 827827Probable beta-glucosidase H
PRO_0000394878

Regions

Domain389 – 533145PA14

Sites

Active site2231 By similarity

Amino acid modifications

Glycosylation4711N-linked (GlcNAc...) Potential
Glycosylation5941N-linked (GlcNAc...) Potential
Glycosylation6001N-linked (GlcNAc...) Potential
Glycosylation6251N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
B8NPL7 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 7E5438F60066A83B

FASTA82790,797
        10         20         30         40         50         60 
MALDIDYVLS HISQEDKIAL LAGIDFWHTH PIPELNVPSI RSTDGPNGIR GTKFFAGVPA 

        70         80         90        100        110        120 
ACLPCGTALA STWDQNLLRE VGVLIGKECL AKGAHCWLGP TINMPRSPLG GRGFESFAED 

       130        140        150        160        170        180 
PHLAGAMAAS MITGCESTGV ISAVKHFVGN DQEHERRAVD VLVTQRALRE IYLRPFQIVA 

       190        200        210        220        230        240 
RDAGPGALMT SYNKINGKHV VESKEMLDMV RQEWKWNPLI MSDWLGTYTT IDSMNAGLDL 

       250        260        270        280        290        300 
EMPGPSRYRG RYVESALQAR LIKESTIDSR ARKVLEFVQQ ASRAPVSAVE TGRDYPEDRA 

       310        320        330        340        350        360 
LNRNLCANSI VLLKNQNDIL PLPKTIKKIA LVGSHVRTPA ISGGGSASLE PYYTVSLYDA 

       370        380        390        400        410        420 
VSEALPHTEI LYEVGAYAHK MLPVIDRLLT NAVMHFYNEP VGTERILRAT QRMSKTAFQL 

       430        440        450        460        470        480 
MDFNAPELNR GLFYATLTGD FTPDVSGVWD FGLTVFGTGL LYVDDELVVD NTTHQTRGTA 

       490        500        510        520        530        540 
FFGKGTVQEL GSKTLNAEQT YKIRIEYGSA NTSPMKAIGV VHFGGGAAHL GACLHVDSAE 

       550        560        570        580        590        600 
MVRSAVKAAA EADYTILCTG LNHEWESEGF DRSHMDLPPG IDALITSVLD VAANKTVIVN 

       610        620        630        640        650        660 
QSGTPVTMPW ADRARGIVQA WYGGNETGHG IADVIFGDVN PSGKLPLSWP VDVKHNPAYL 

       670        680        690        700        710        720 
NYASVGGRVL YGEDVYVGYR YYEKVGREVL FPFGHGLSYT TFTVSPDVVF SQEVFRPEEP 

       730        740        750        760        770        780 
PTAAVKIKNT GKVAGAQVLQ LYISAPHSPT PRPTKELHGF TKVLLQPGEE RVAHIRMDKY 

       790        800        810        820 
ATNFWDEIEG MWKSEEGIYE ALIGTSSQNI LAKGTFRVDR TRYWLGL 

« Hide

References

[1]"Genome sequence of Aspergillus flavus strain NRRL 3357."
Payne W.G.A., Dean R.A., Nierman W.C., Amedeo P., Caler E.G.A., Fedorova N.D., Maiti R., Joardar V., Inman J., Galinsky K.J., Yu J., Bhatnagar D., Cleveland T.E.
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EQ963482 Genomic DNA. Translation: EED47440.1.
RefSeqXP_002382282.1. XM_002382241.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAFLAT00010147; CADAFLAP00010147; CADAFLAG00010147.
GeneID7921794.
KEGGafv:AFLA_000810.

Phylogenomic databases

eggNOGCOG1472.
HOGENOMHOG000031215.
OMAGCESTGV.
OrthoDBEOG7H799Q.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 2 hits.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
IPR011658. PA14.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
PF07691. PA14. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SMARTSM00758. PA14. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
ProtoNetSearch...

Entry information

Entry nameBGLH_ASPFN
AccessionPrimary (citable) accession number: B8NPL7
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: March 3, 2009
Last modified: February 19, 2014
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries