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Protein

Hexokinase

Gene

AFLA_130070

Organism
Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
ORF Names:AFLA_130070Imported
OrganismiAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)Imported
Taxonomic identifieri332952 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
ProteomesiUP000001875 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:AFLA_130070.

Structurei

3D structure databases

ProteinModelPortaliB8NPD5.
SMRiB8NPD5. Positions 18-481.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000162670.
KOiK00844.
OMAiDICQSKY.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8NPD5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGIGPKRPP SRKGSMHELP QNLLEQIKQF EDIFTVDGAK LKQIADHFVK
60 70 80 90 100
ELEKGLSVEG GNIPMNVTWV MGFPDGDEQG TFLALDMGGT NLRVCEITLT
110 120 130 140 150
EEKGAFDITQ SKYRMPEELK TGTAEELWEY IADCLQQFIE SHHENEKLSK
160 170 180 190 200
LPLGFTFSYP ATQEYIDHGV LQRWTKGFDI DGVEGQDVVP PLEAILKKRG
210 220 230 240 250
LPIKVAALIN DTTGTLIASS YTDSDMKIGC IFGTGVNAAY MEHCGSVPKL
260 270 280 290 300
AHKNLPPDMP VAINCEYGAF DNEHVVLPLT KYDIIIDRDS PRPGQQAFEK
310 320 330 340 350
MTAGLYLGEI FRLALLDLLE TRPGLIFQGQ DTSQLRKPYL LDASFLAAIE
360 370 380 390 400
DDPYENLQET QELMERKLNI KATQQELEMI RRLAELIGTR AARLSACGVA
410 420 430 440 450
AICKKKNIES CHVGADGSVF TKYPHFKARG AQALREILDW APNEKDKVVI
460 470 480 490
MAAEDGSGVG AALIAALTLK RVKAGISCGI RDMADMQSLI
Length:490
Mass (Da):54,147
Last modified:March 3, 2009 - v1
Checksum:i28B891A5E6E37FF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ963481 Genomic DNA. Translation: EED48784.1.
RefSeqiXP_002382200.1. XM_002382159.1.

Genome annotation databases

EnsemblFungiiCADAFLAT00010065; CADAFLAP00010065; CADAFLAG00010065.
GeneIDi7913704.
KEGGiafv:AFLA_130070.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ963481 Genomic DNA. Translation: EED48784.1.
RefSeqiXP_002382200.1. XM_002382159.1.

3D structure databases

ProteinModelPortaliB8NPD5.
SMRiB8NPD5. Positions 18-481.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCADAFLAT00010065; CADAFLAP00010065; CADAFLAG00010065.
GeneIDi7913704.
KEGGiafv:AFLA_130070.

Organism-specific databases

EuPathDBiFungiDB:AFLA_130070.

Phylogenomic databases

HOGENOMiHOG000162670.
KOiK00844.
OMAiDICQSKY.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of Aspergillus flavus strain NRRL 3357."
    Payne W.G.A., Dean R.A., Nierman W.C., Amedeo P., Caler E.G.A., Fedorova N.D., Maiti R., Joardar V., Inman J., Galinsky K.J., Yu J., Bhatnagar D., Cleveland T.E.
    Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167Imported.

Entry informationi

Entry nameiB8NPD5_ASPFN
AccessioniPrimary (citable) accession number: B8NPD5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 22, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.