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Protein

Probable beta-glucosidase F

Gene

bglF

Organism
Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose (By similarity).By similarity

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathwayi: cellulose degradation

This protein is involved in the pathway cellulose degradation, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway cellulose degradation and in Glycan metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei285By similarity1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

UniPathwayiUPA00696.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable beta-glucosidase F (EC:3.2.1.21)
Alternative name(s):
Beta-D-glucoside glucohydrolase F
Cellobiase F
Gentiobiase F
Gene namesi
Name:bglF
ORF Names:AFLA_128480
OrganismiAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Taxonomic identifieri332952 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000001875 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:AFLA_128480.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_000039411021 – 866Probable beta-glucosidase FAdd BLAST846

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi65N-linked (GlcNAc...)Sequence analysis1
Glycosylationi73N-linked (GlcNAc...)Sequence analysis1
Glycosylationi257N-linked (GlcNAc...)Sequence analysis1
Glycosylationi328N-linked (GlcNAc...)Sequence analysis1
Glycosylationi360N-linked (GlcNAc...)Sequence analysis1
Glycosylationi395N-linked (GlcNAc...)Sequence analysis1
Glycosylationi421N-linked (GlcNAc...)Sequence analysis1
Glycosylationi474N-linked (GlcNAc...)Sequence analysis1
Glycosylationi659N-linked (GlcNAc...)Sequence analysis1
Glycosylationi664N-linked (GlcNAc...)Sequence analysis1
Glycosylationi724N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliB8NP65.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000031215.
OMAiNEQEMYR.
OrthoDBiEOG092C0ZJY.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 3 hits.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SMARTiSM01217. Fn3_like. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 1 hit.
PROSITEiPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B8NP65-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAFPAYLAL LSYLVPGALS HPEAKTLTSR ASTEAYSPPY YPAPNGGWIS
60 70 80 90 100
EWASAYEKAH RVVSNMTLAE KVNLTSGTGI YMGPCAGQTG SVPRFGIPNL
110 120 130 140 150
CLHDSPLGVR NSDHNTAFPA GITVGATFDK DLMYERGVGL GEEARGKGIN
160 170 180 190 200
VLLGPSVGPI GRKPRGGRNW EGFGADPSLQ AFGGSLTIKG MQSTGAIASL
210 220 230 240 250
KHLIGNEQEQ HRMSSVITQG YSSNIDDRTL HELYLWPFAE SVRAGAGSVM
260 270 280 290 300
IAYNDVNRSA CSQNSKLING ILKDELGFQG FVVTDWLAHI GGVSSALAGL
310 320 330 340 350
DMSMPGDGAI PLLGTSYWSW ELSRSVLNGS VPVERLNDMV TRIVATWYKM
360 370 380 390 400
GQDKDYPLPN FSSNTEDETG PLYPGALFSP SGIVNQYVNV QGNHNVTARA
410 420 430 440 450
IARDAITLLK NNDNVLPLKR NNTLKIFGTD AGTNSDGINS CTDKGCNKGV
460 470 480 490 500
LTMGWGSGTS RLPYLITPQE AIANISSNAG FHITDTFPSG VTAGPDDIAI
510 520 530 540 550
VFINSDSGEN YITVDGNPGD RTLAGLHAWH NGDNLVKAAA EKFSNVVVVV
560 570 580 590 600
HTVGPILMEE WIDLDSVKAV LVAHLPGQEA GWSLTDILFG DYSPSGHLPY
610 620 630 640 650
TIPHSESDYP ESVGLIAQPF GQIQDDYTEG LYIDYRHFLK ANITPRYPFG
660 670 680 690 700
HGLSYTTFNF TEPNLSIIKA LDTAYPAARP PKGSTPTYPT AKPDASEVAW
710 720 730 740 750
PKNFNRIWRY LYPYLDNPEG AAANSSKTYP YPDGYTTEPK PAPRAGGAEG
760 770 780 790 800
GNPALWDVTF SVQVKVTNTG SRDGRAVAQL YVELPSSLGL DTPSRQLRQF
810 820 830 840 850
EKTKILAAGE SEVLTLDVTR KDLSVWDVVV QDWKAPVNGE GVKIWVGESV
860
ADLRVGCVVG EGCSTL
Length:866
Mass (Da):93,066
Last modified:March 3, 2009 - v1
Checksum:i02697819B5DDB341
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ963481 Genomic DNA. Translation: EED48625.1.
RefSeqiXP_002382041.1. XM_002382000.1.

Genome annotation databases

EnsemblFungiiEED48625; EED48625; AFLA_128480.
GeneIDi7921713.
KEGGiafv:AFLA_128480.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ963481 Genomic DNA. Translation: EED48625.1.
RefSeqiXP_002382041.1. XM_002382000.1.

3D structure databases

ProteinModelPortaliB8NP65.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiEED48625; EED48625; AFLA_128480.
GeneIDi7921713.
KEGGiafv:AFLA_128480.

Organism-specific databases

EuPathDBiFungiDB:AFLA_128480.

Phylogenomic databases

HOGENOMiHOG000031215.
OMAiNEQEMYR.
OrthoDBiEOG092C0ZJY.

Enzyme and pathway databases

UniPathwayiUPA00696.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 3 hits.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SMARTiSM01217. Fn3_like. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 1 hit.
PROSITEiPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBGLF_ASPFN
AccessioniPrimary (citable) accession number: B8NP65
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: March 3, 2009
Last modified: November 2, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.