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B8NNI2

- GANA_ASPFN

UniProt

B8NNI2 - GANA_ASPFN

Protein

Probable arabinogalactan endo-beta-1,4-galactanase A

Gene

galA

Organism
Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 33 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Endogalactanase involved in the degradation of plant cell wall polysaccharides, and more particularly of hairy regions of pectin.By similarity

    Catalytic activityi

    The enzyme specifically hydrolyzes (1->4)-beta-D-galactosidic linkages in type I arabinogalactans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei150 – 1501Proton donorBy similarity
    Active sitei260 – 2601NucleophileBy similarity

    GO - Molecular functioni

    1. arabinogalactan endo-1,4-beta-galactosidase activity Source: UniProtKB
    2. glucosidase activity Source: InterPro

    GO - Biological processi

    1. pectin catabolic process Source: UniProtKB

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable arabinogalactan endo-beta-1,4-galactanase A (EC:3.2.1.89)
    Alternative name(s):
    Endo-1,4-beta-galactanase A
    Short name:
    Galactanase A
    Gene namesi
    Name:galA
    ORF Names:AFLA_127930
    OrganismiAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
    Taxonomic identifieri332952 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000001875: Unassembled WGS sequence

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1616Sequence AnalysisAdd
    BLAST
    Chaini17 – 347331Probable arabinogalactan endo-beta-1,4-galactanase APRO_0000394945Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliB8NNI2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 53 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG3867.
    HOGENOMiHOG000217077.
    KOiK01224.
    OMAiTLHYSDS.
    OrthoDBiEOG7CG78S.

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR011683. Glyco_hydro_53.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF07745. Glyco_hydro_53. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    B8NNI2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLFSYLLATL PLLANAALTY KGADISSVFI EEKAGVAYKN LAGETQALEA    50
    ILTDNGVNSI RQRVWVKNGD YDLTYNVNLA KRVAATGASI YLDLHYSDDW 100
    ADPKHQTTPD GWSTDDINTL ADQIYQYTLS VCNTFAEEKI NVEIVSIGNE 150
    ITSGLLWPLG KTPNYENIAR LLHSGAWGVK DSKLATKPKI LIHLDNGWDW 200
    DQQKYFYDTA LGTGLLTSDD FDMIGVSYYP FYNEKATLAS LKTSLTNIQT 250
    TYGKEVAVVE TNWPVKCSSP EFAFPADLKD IPFSVDGQVT FLQRLADTLT 300
    ATKASGFFYW EPAWTKNAGL GSSCEDNLLV DYNTNQVRSS VKAFGQV 347
    Length:347
    Mass (Da):38,452
    Last modified:March 3, 2009 - v1
    Checksum:i3FE2B51673D9AB41
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EQ963481 Genomic DNA. Translation: EED48570.1.
    RefSeqiXP_002381986.1. XM_002381945.1.

    Genome annotation databases

    EnsemblFungiiCADAFLAT00009851; CADAFLAP00009851; CADAFLAG00009851.
    GeneIDi7920353.
    KEGGiafv:AFLA_127930.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EQ963481 Genomic DNA. Translation: EED48570.1 .
    RefSeqi XP_002381986.1. XM_002381945.1.

    3D structure databases

    ProteinModelPortali B8NNI2.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADAFLAT00009851 ; CADAFLAP00009851 ; CADAFLAG00009851 .
    GeneIDi 7920353.
    KEGGi afv:AFLA_127930.

    Phylogenomic databases

    eggNOGi COG3867.
    HOGENOMi HOG000217077.
    KOi K01224.
    OMAi TLHYSDS.
    OrthoDBi EOG7CG78S.

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR011683. Glyco_hydro_53.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF07745. Glyco_hydro_53. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Aspergillus flavus strain NRRL 3357."
      Payne W.G.A., Dean R.A., Nierman W.C., Amedeo P., Caler E.G.A., Fedorova N.D., Maiti R., Joardar V., Inman J., Galinsky K.J., Yu J., Bhatnagar D., Cleveland T.E.
      Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167.

    Entry informationi

    Entry nameiGANA_ASPFN
    AccessioniPrimary (citable) accession number: B8NNI2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 15, 2010
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 33 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3