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B8NJF4 (BGLD_ASPFN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 29. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase D

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase D
Cellobiase D
Gentiobiase D
Gene names
Name:bglD
ORF Names:AFLA_066750
OrganismAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) [Complete proteome]
Taxonomic identifier332952 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length752 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Sequence caution

The sequence EED49853.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1818 Potential
Chain19 – 752734Probable beta-glucosidase D
PRO_0000394106

Sites

Active site2651 By similarity

Amino acid modifications

Glycosylation1871N-linked (GlcNAc...) Potential
Glycosylation2371N-linked (GlcNAc...) Potential
Glycosylation2991N-linked (GlcNAc...) Potential
Glycosylation3431N-linked (GlcNAc...) Potential
Glycosylation4411N-linked (GlcNAc...) Potential
Glycosylation5101N-linked (GlcNAc...) Potential
Glycosylation5321N-linked (GlcNAc...) Potential
Glycosylation5711N-linked (GlcNAc...) Potential
Glycosylation5861N-linked (GlcNAc...) Potential
Glycosylation6381N-linked (GlcNAc...) Potential
Glycosylation6611N-linked (GlcNAc...) Potential
Glycosylation7431N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
B8NJF4 [UniParc].

Last modified May 18, 2010. Version 2.
Checksum: EF4A1C9545347B7A

FASTA75280,200
        10         20         30         40         50         60 
MRFVSLAVGA ALLGAAGASS ISSNVGLLKA NGVALGNWEA AYEKASAFVS GLTTDQKLAL 

        70         80         90        100        110        120 
ITGSNVESTN GNFTPLYFLD GDMGLQDFYY VSAFSLSSAL AMTWDRDAIY EQAKAVGSEF 

       130        140        150        160        170        180 
YNKGVQVVAG PTSQPLGRTP WGGRGVEGFG PDPYLNGLAT GLTTKGYVDA GVIPGGKHFL 

       190        200        210        220        230        240 
LYEQETNRTS SFGSSGEGSP YSSNADDKTI HETYLWPFYD AVKNGAGAVM CAMTKVNGTM 

       250        260        270        280        290        300 
ACENSDLLMK MLKTELGFPG MVWPDMNGQN SAKGSALGGE DYGSSSIWST STMESFLSNG 

       310        320        330        340        350        360 
TLSEARLNDM AIRNLIGYYY VNLDNGRQPT RQTTDVYVDV RANHSKLIRE NGAKSMALLK 

       370        380        390        400        410        420 
NEGVLPLSKP RVMSIFGAHA GPIMGGPNSN VDVMGSGPTY QGHLATGSGS GMASMPYLIT 

       430        440        450        460        470        480 
PYGALTNKAA QDGTVLRWVL NDTYSSGGGS SLVPSSTSST AVEPSFENFA TGSDICLVFI 

       490        500        510        520        530        540 
NALAGEGADR TELYNADQDA MVNTVADNCN NTVAVVNTVG PRLLDQWIEH DNVTAVLYGS 

       550        560        570        580        590        600 
LLGQESGNSI VDLLYGDVNP SGRLVHTIAK NESDYNVGLC YTAQCNFTEG VYLDYRYFDA 

       610        620        630        640        650        660 
HNITPRYPFG HGLSYTTFHY SSLAIKAPSS ITKAPKGNLT VGGPSDLWDV VGTVSARIAN 

       670        680        690        700        710        720 
NGTLSGAEVP QLYLGFPDSA DQPVRQLRGF DRVELSAGQE AVVTFNLRRR DISYWNVKTQ 

       730        740        750 
QWMVAGGKYT VFVGGSSRDL RLNGTFFLWV GS 

« Hide

References

[1]"Genome sequence of Aspergillus flavus strain NRRL 3357."
Payne W.G.A., Dean R.A., Nierman W.C., Amedeo P., Caler E.G.A., Fedorova N.D., Maiti R., Joardar V., Inman J., Galinsky K.J., Yu J., Bhatnagar D., Cleveland T.E.
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EQ963479 Genomic DNA. Translation: EED49853.1. Sequence problems.
RefSeqXP_002380234.1. XM_002380193.1.

3D structure databases

ProteinModelPortalB8NJF4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7921102.
KEGGafv:AFLA_066750.

Phylogenomic databases

eggNOGCOG1472.
HOGENOMHOG000031215.
OrthoDBEOG7XH6ZD.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBGLD_ASPFN
AccessionPrimary (citable) accession number: B8NJF4
Entry history
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: May 18, 2010
Last modified: February 19, 2014
This is version 29 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries