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B8NGU6 (BGLC_ASPFN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase C

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase C
Cellobiase C
Gentiobiase C
Gene names
Name:bglC
ORF Names:AFLA_138140
OrganismAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) [Complete proteome]
Taxonomic identifier332952 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length634 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 634615Probable beta-glucosidase C
PRO_0000394103

Sites

Active site3371 By similarity

Amino acid modifications

Glycosylation901N-linked (GlcNAc...) Potential
Glycosylation1121N-linked (GlcNAc...) Potential
Glycosylation2191N-linked (GlcNAc...) Potential
Glycosylation2701N-linked (GlcNAc...) Potential
Glycosylation3601N-linked (GlcNAc...) Potential
Glycosylation4761N-linked (GlcNAc...) Potential
Glycosylation4841N-linked (GlcNAc...) Potential
Glycosylation5241N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
B8NGU6 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: FCF6E0543CFD1F49

FASTA63470,145
        10         20         30         40         50         60 
MRIDCTVASL TALASGCQAL STRPYVPRGH SLSRRDDSAP IYRDASYCID ERVDDLLARM 

        70         80         90        100        110        120 
TIEEKAGQLF HTRLMDGPLD DEGSGNNAHN STSNMIGEKH MTHFNLASDI TNATETAEFI 

       130        140        150        160        170        180 
NRIQELALQT RLGIPVTVST DPRHSFTENV GTGFKAGVFS QWPESIGLAA LRDPYVVRKF 

       190        200        210        220        230        240 
AEVAKEEYIA VGIRAALHPQ VDLSTEPRWA RISNTWGENS TLTSELLVEY IKGFQGDKLG 

       250        260        270        280        290        300 
PQSVKTVTKH FPGGGPVENG EDSHFAYGKN QTYPGNNLEE HLKPFKAAIA AGATEIMPYY 

       310        320        330        340        350        360 
SRPIGTEYEP VAFSFNKRIV TELLRNELGF EGIVLTDWGL ITDGYIAGQY MPARAWGVEN 

       370        380        390        400        410        420 
LTELERAARI LDAGCDQFGG EERPELIVQL VQEGTVSEDR IDVSVRRLLR EKFVLGLFDN 

       430        440        450        460        470        480 
PFVDPESAGR VVGNDYFVRL GREAQRRSYT LLSNNEDIVP LKKIEQSTKF YIEGFNASFI 

       490        500        510        520        530        540 
ESWNYTVVDS PEEADYALLR YNAPYEPRPG GFEANMHAGS LAFNDTEKAR QAKIYSTVPT 

       550        560        570        580        590        600 
IVDIVMDRPA VIPEIIEQAK AVFASYGSDS NAFLDVVFGV SAPEGKLPFD LPSSMEAVEA 

       610        620        630 
QMEDVPFDTR NPVFKFGHGL SYANPCASSS SKCS 

« Hide

References

[1]"Genome sequence of Aspergillus flavus strain NRRL 3357."
Payne W.G.A., Dean R.A., Nierman W.C., Amedeo P., Caler E.G.A., Fedorova N.D., Maiti R., Joardar V., Inman J., Galinsky K.J., Yu J., Bhatnagar D., Cleveland T.E.
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EQ963478 Genomic DNA. Translation: EED51050.1.
RefSeqXP_002379826.1. XM_002379785.1.

3D structure databases

ProteinModelPortalB8NGU6.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAFLAT00007691; CADAFLAP00007691; CADAFLAG00007691.
GeneID7915545.
KEGGafv:AFLA_138140.

Phylogenomic databases

eggNOGCOG1472.
HOGENOMHOG000285275.
OMAHWVGYGA.
OrthoDBEOG7R8394.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026892. Glyco_hydro_3.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 1 hit.
ProtoNetSearch...

Entry information

Entry nameBGLC_ASPFN
AccessionPrimary (citable) accession number: B8NGU6
Entry history
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: March 3, 2009
Last modified: May 14, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries