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B8NGU6

- BGLC_ASPFN

UniProt

B8NGU6 - BGLC_ASPFN

Protein

Probable beta-glucosidase C

Gene

bglC

Organism
Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 31 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.By similarity

    Catalytic activityi

    Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei337 – 3371By similarity

    GO - Molecular functioni

    1. beta-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Enzyme and pathway databases

    UniPathwayiUPA00696.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable beta-glucosidase C (EC:3.2.1.21)
    Alternative name(s):
    Beta-D-glucoside glucohydrolase C
    Cellobiase C
    Gentiobiase C
    Gene namesi
    Name:bglC
    ORF Names:AFLA_138140
    OrganismiAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
    Taxonomic identifieri332952 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
    ProteomesiUP000001875: Unassembled WGS sequence

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919Sequence AnalysisAdd
    BLAST
    Chaini20 – 634615Probable beta-glucosidase CPRO_0000394103Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi90 – 901N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi112 – 1121N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi219 – 2191N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi270 – 2701N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi360 – 3601N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi476 – 4761N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi484 – 4841N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi524 – 5241N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Structurei

    3D structure databases

    ProteinModelPortaliB8NGU6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 3 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    eggNOGiCOG1472.
    HOGENOMiHOG000285275.
    OMAiHWVGYGA.
    OrthoDBiEOG7R8394.

    Family and domain databases

    Gene3Di3.20.20.300. 1 hit.
    3.40.50.1700. 1 hit.
    InterProiIPR026892. Glyco_hydro_3.
    IPR002772. Glyco_hydro_3_C.
    IPR001764. Glyco_hydro_3_N.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PANTHERiPTHR30620. PTHR30620. 1 hit.
    PfamiPF00933. Glyco_hydro_3. 1 hit.
    PF01915. Glyco_hydro_3_C. 1 hit.
    [Graphical view]
    PRINTSiPR00133. GLHYDRLASE3.
    SUPFAMiSSF51445. SSF51445. 1 hit.
    SSF52279. SSF52279. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    B8NGU6-1 [UniParc]FASTAAdd to Basket

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    MRIDCTVASL TALASGCQAL STRPYVPRGH SLSRRDDSAP IYRDASYCID    50
    ERVDDLLARM TIEEKAGQLF HTRLMDGPLD DEGSGNNAHN STSNMIGEKH 100
    MTHFNLASDI TNATETAEFI NRIQELALQT RLGIPVTVST DPRHSFTENV 150
    GTGFKAGVFS QWPESIGLAA LRDPYVVRKF AEVAKEEYIA VGIRAALHPQ 200
    VDLSTEPRWA RISNTWGENS TLTSELLVEY IKGFQGDKLG PQSVKTVTKH 250
    FPGGGPVENG EDSHFAYGKN QTYPGNNLEE HLKPFKAAIA AGATEIMPYY 300
    SRPIGTEYEP VAFSFNKRIV TELLRNELGF EGIVLTDWGL ITDGYIAGQY 350
    MPARAWGVEN LTELERAARI LDAGCDQFGG EERPELIVQL VQEGTVSEDR 400
    IDVSVRRLLR EKFVLGLFDN PFVDPESAGR VVGNDYFVRL GREAQRRSYT 450
    LLSNNEDIVP LKKIEQSTKF YIEGFNASFI ESWNYTVVDS PEEADYALLR 500
    YNAPYEPRPG GFEANMHAGS LAFNDTEKAR QAKIYSTVPT IVDIVMDRPA 550
    VIPEIIEQAK AVFASYGSDS NAFLDVVFGV SAPEGKLPFD LPSSMEAVEA 600
    QMEDVPFDTR NPVFKFGHGL SYANPCASSS SKCS 634
    Length:634
    Mass (Da):70,145
    Last modified:March 3, 2009 - v1
    Checksum:iFCF6E0543CFD1F49
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EQ963478 Genomic DNA. Translation: EED51050.1.
    RefSeqiXP_002379826.1. XM_002379785.1.

    Genome annotation databases

    EnsemblFungiiCADAFLAT00007691; CADAFLAP00007691; CADAFLAG00007691.
    GeneIDi7915545.
    KEGGiafv:AFLA_138140.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EQ963478 Genomic DNA. Translation: EED51050.1 .
    RefSeqi XP_002379826.1. XM_002379785.1.

    3D structure databases

    ProteinModelPortali B8NGU6.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii CADAFLAT00007691 ; CADAFLAP00007691 ; CADAFLAG00007691 .
    GeneIDi 7915545.
    KEGGi afv:AFLA_138140.

    Phylogenomic databases

    eggNOGi COG1472.
    HOGENOMi HOG000285275.
    OMAi HWVGYGA.
    OrthoDBi EOG7R8394.

    Enzyme and pathway databases

    UniPathwayi UPA00696 .

    Family and domain databases

    Gene3Di 3.20.20.300. 1 hit.
    3.40.50.1700. 1 hit.
    InterProi IPR026892. Glyco_hydro_3.
    IPR002772. Glyco_hydro_3_C.
    IPR001764. Glyco_hydro_3_N.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    PANTHERi PTHR30620. PTHR30620. 1 hit.
    Pfami PF00933. Glyco_hydro_3. 1 hit.
    PF01915. Glyco_hydro_3_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00133. GLHYDRLASE3.
    SUPFAMi SSF51445. SSF51445. 1 hit.
    SSF52279. SSF52279. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Aspergillus flavus strain NRRL 3357."
      Payne W.G.A., Dean R.A., Nierman W.C., Amedeo P., Caler E.G.A., Fedorova N.D., Maiti R., Joardar V., Inman J., Galinsky K.J., Yu J., Bhatnagar D., Cleveland T.E.
      Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167.

    Entry informationi

    Entry nameiBGLC_ASPFN
    AccessioniPrimary (citable) accession number: B8NGU6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 18, 2010
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 31 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3