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B8NDE2 (BGLI_ASPFN) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase I

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase I
Cellobiase I
Gentiobiase I
Gene names
Name:bglI
ORF Names:AFLA_057030
OrganismAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) [Complete proteome]
Taxonomic identifier332952 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length839 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Contains 1 PA14 domain.

Sequence caution

The sequence EED51440.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 839839Probable beta-glucosidase I
PRO_0000394885

Regions

Domain433 – 52189PA14

Sites

Active site2251 By similarity

Amino acid modifications

Glycosylation1971N-linked (GlcNAc...) Potential
Glycosylation6201N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
B8NDE2 [UniParc].

Last modified June 15, 2010. Version 2.
Checksum: E52897D374F30765

FASTA83992,082
        10         20         30         40         50         60 
MPRLDVEKTI EELSLGEKVA LTAGIDFWHT ASVPRLNIPT LRMSDGPNGV RGTRFFNGVP 

        70         80         90        100        110        120 
AACFPCATAL GATWDTELLH EIGQLMGEES IAKGSHIILG PTINTQRSPL GGRGFESFAE 

       130        140        150        160        170        180 
DGVLSGLLAG YISKGIQEKG VAATLKHFVC NDQEHQRMAV DSIVTQRALR EIYLLPFQLA 

       190        200        210        220        230        240 
MRICRTACVM TAYNKVNGTH VSQNKEIITD ILRKEWGWDG LVMSDWFGTY STSDAINAGL 

       250        260        270        280        290        300 
DLEMPGKTRW RGTALAHAVS SNEVAEFVMD ERVRNVLNLV NFVDGLNIPE NAPEKALNRP 

       310        320        330        340        350        360 
QDQALLRRAA AESVVLMKNE EDILPLKKEK SILVIGPNSK VAAYCGGGSA SLDAYYTVNP 

       370        380        390        400        410        420 
FEGVSAQSKG EVKFSQGVYS HKDLPLLGPL LKTADGKTGF SFKVYNEHPS ESNRELIEQL 

       430        440        450        460        470        480 
HLVSSSGFLM DYVNPKIKSL TYYVDMEGLF TPEEDGVYDF GVTVVGTGQL FIDGELVVDN 

       490        500        510        520        530        540 
TKNQRQGSAF FGSATVEEKG SKELKAGQTY KVLFQFGTAP TSDLDTRGVV VFGPGGFRFG 

       550        560        570        580        590        600 
ASRRVGQEEL ISNAVKLASE AEQVVVFAGL TSEWETEGYD RDHMDLPPGS DEMISRVLDV 

       610        620        630        640        650        660 
NPNAVVVIQS GTPVTMPWAN KTKALLHAWF GGNECGNGIA DVLYGDVNPS GKLPITFPVR 

       670        680        690        700        710        720 
LQDNPSYVNF RSERGRVLYG EDVYVGYRYY EKVDLAPLFP FGHGLSYTTF TRSDLTLTTT 

       730        740        750        760        770        780 
PEKPQYEESG EPITATVTVT NTGKVAGAEI VQLWVAPPAT EVNRPVRELK GFTKVFLQPG 

       790        800        810        820        830 
EQKKVEIVVE KKLATSWFDE MREKWASEKG EYGVLVTGTG EGVLKSSFKV EKTRYWLGL 

« Hide

References

[1]"Genome sequence of Aspergillus flavus strain NRRL 3357."
Payne W.G.A., Dean R.A., Nierman W.C., Amedeo P., Caler E.G.A., Fedorova N.D., Maiti R., Joardar V., Inman J., Galinsky K.J., Yu J., Bhatnagar D., Cleveland T.E.
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EQ963477 Genomic DNA. Translation: EED51440.1. Sequence problems.
RefSeqXP_002378447.1. XM_002378406.1.

3D structure databases

ProteinModelPortalB8NDE2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5059.CADAFLAP00006312.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7916501.
KEGGafv:AFLA_057030.

Phylogenomic databases

eggNOGCOG1472.
HOGENOMHOG000031215.
KOK05349.
OrthoDBEOG7H799Q.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 2 hits.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
IPR011658. PA14.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
PF07691. PA14. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SMARTSM00758. PA14. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGLI_ASPFN
AccessionPrimary (citable) accession number: B8NDE2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 15, 2010
Last sequence update: June 15, 2010
Last modified: February 19, 2014
This is version 34 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries