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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)]

Gene

AFLA_046760

Organism
Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei46NADUniRule annotation1
Binding sitei116NADUniRule annotation1
Binding sitei139SubstrateUniRule annotation1
Binding sitei172NAD; via amide nitrogenUniRule annotation1
Active sitei265Proton acceptorUniRule annotation1
Binding sitei331NADUniRule annotation1
Binding sitei358NAD; via amide nitrogenUniRule annotation1
Binding sitei360NADUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi14 – 19NADUniRule annotation6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
LigandNADUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)]UniRule annotation (EC:1.1.1.8UniRule annotation)
Gene namesi
ORF Names:AFLA_046760Imported
OrganismiAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)Imported
Taxonomic identifieri332952 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000001875 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:AFLA_046760

Subcellular locationi

Interactioni

Protein-protein interaction databases

STRINGi5059.CADAFLAP00006003

Structurei

3D structure databases

ProteinModelPortaliB8NBV1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 189NAD_Gly3P_dh_NInterPro annotationAdd BLAST180
Domaini254 – 388NAD_Gly3P_dh_CInterPro annotationAdd BLAST135

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni331 – 332Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000246855
KOiK00006
OMAiPHQFIHK
OrthoDBiEOG092C3ZQP

Family and domain databases

Gene3Di1.10.1040.10, 1 hit
InterProiView protein in InterPro
IPR008927 6-PGluconate_DH-like_C_sf
IPR013328 6PGD_dom2
IPR006168 G3P_DH_NAD-dep
IPR006109 G3P_DH_NAD-dep_C
IPR011128 G3P_DH_NAD-dep_N
IPR036291 NAD(P)-bd_dom_sf
PfamiView protein in Pfam
PF07479 NAD_Gly3P_dh_C, 1 hit
PF01210 NAD_Gly3P_dh_N, 1 hit
PIRSFiPIRSF000114 Glycerol-3-P_dh, 1 hit
PRINTSiPR00077 GPDHDRGNASE
SUPFAMiSSF48179 SSF48179, 1 hit
SSF51735 SSF51735, 2 hits
PROSITEiView protein in PROSITE
PS00957 NAD_G3PDH, 1 hit

Sequencei

Sequence statusi: Complete.

B8NBV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPQQKKQHTV AVIGSGNWGS TIAKILAENT ASHPELFTPK VQMWVFEEQI
60 70 80 90 100
QIPSDSPHHS KYGDKPQNLT EVINAVHENV KYLPGIRLPE NVVANPNLED
110 120 130 140 150
VVKDATILVF NLPHQFIEKT LDQIKGKHLP YARAISCVKG VDVTDGMVTL
160 170 180 190 200
FSELIMEKLA IYCGSLSGAN IAPEVAAEKF SETTIGYDTP PMDVKAEDGS
210 220 230 240 250
PEDNKIKIDE QRQVKTRPTH TKLTRVPQEL VTVDAELWRT LFGRPYFHVN
260 270 280 290 300
VVDDVAGVAL SGALKNIVAL AAGFVAGKGW GENGKAAVIR VGVVEMVKFG
310 320 330 340 350
RTWFPQSVNE RTFTEESAGI ADLVASCSAG RNFRSAKHAV EKGVNVDEIE
360 370 380 390
KTEMNGQKLQ GTSTAKSVHE FLEKHGKVQD FPLFDAVYGE SRL
Length:393
Mass (Da):43,168
Last modified:March 3, 2009 - v1
Checksum:iAA9DF76E52AA30BC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ963476 Genomic DNA Translation: EED52974.1
RefSeqiXP_002378138.1, XM_002378097.1

Genome annotation databases

EnsemblFungiiEED52974; EED52974; AFLA_046760
GeneIDi7914569
KEGGiafv:AFLA_046760

Similar proteinsi

Entry informationi

Entry nameiB8NBV1_ASPFN
AccessioniPrimary (citable) accession number: B8NBV1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 59 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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