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B8N2K9 (B8N2K9_ASPFN) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length260 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity By similarity. RuleBase RU004203

Catalytic activity

Cleavage of peptide bonds with very broad specificity. RuleBase RU000694

Subunit structure

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits By similarity.

Subcellular location

Cytoplasm. Nucleus By similarity SAAS SAAS016050 RuleBase RU000694.

Sequence similarities

Belongs to the peptidase T1B family. RuleBase RU004202

Sequences

Sequence LengthMass (Da)Tools
B8N2K9 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 09E7B436D0CFB0B5

FASTA26028,946
        10         20         30         40         50         60 
MNHYPEVWGR PRDDIYGPYN SSYLQTTGSK THTQSPAVTG TSVIAVKFNG GVAIAADNLA 

        70         80         90        100        110        120 
SYGSLARFTD VKRLRVFGDS AVVGFSGDVS DMQYIDRLLE SLDIRENYST HGNMMNAKNL 

       130        140        150        160        170        180 
HTYLSKVLYK RRSEFNPLWN HILVAGFDED KKPFLSSADL LGTTYSAPHL ATGFGAHLAI 

       190        200        210        220        230        240 
PILRRLFPEE KPLEEISKGE AEAALRECLK VLWYRDARSL DKYSIAVITA EGVEIKEDQV 

       250        260 
IEAQSWAFAE SIRGYGAQVN 

« Hide

References

[1]"Genome sequence of Aspergillus flavus strain NRRL 3357."
Payne W.G.A., Dean R.A., Nierman W.C., Amedeo P., Caler E.G.A., Fedorova N.D., Maiti R., Joardar V., Inman J., Galinsky K.J., Yu J., Bhatnagar D., Cleveland T.E.
Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
EQ963473 Genomic DNA. Translation: EED56510.1.
RefSeqXP_002375292.1. XM_002375251.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5059.CADAFLAP00003157.

Proteomic databases

PRIDEB8N2K9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAFLAT00003157; CADAFLAP00003157; CADAFLAG00003157.
GeneID7919747.
KEGGafv:AFLA_037840.

Phylogenomic databases

HOGENOMHOG000181719.
KOK02736.
OMARIMRVND.
OrthoDBEOG73BVQ8.

Family and domain databases

Gene3D3.60.20.10. 1 hit.
InterProIPR029055. Ntn_hydrolases_N.
IPR016050. Proteasome_bsu_CS.
IPR016295. Proteasome_endopept_cplx_B.
IPR001353. Proteasome_sua/b.
IPR023333. Proteasome_suB-type.
[Graphical view]
PfamPF00227. Proteasome. 1 hit.
[Graphical view]
PIRSFPIRSF001213. Psome_endopept_beta. 1 hit.
SUPFAMSSF56235. SSF56235. 1 hit.
PROSITEPS00854. PROTEASOME_BETA_1. 1 hit.
PS51476. PROTEASOME_BETA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8N2K9_ASPFN
AccessionPrimary (citable) accession number: B8N2K9
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 11, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)