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Protein

Probable glucan 1,3-beta-glucosidase A

Gene

exgA

Organism
Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. It could also function biosynthetically as a transglycosylase (By similarity).By similarity

Catalytic activityi

Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.

Cofactori

Mn2+By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei199Proton donorBy similarity1
Active sitei298NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Cell wall biogenesis/degradation, Polysaccharide degradation
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glucan 1,3-beta-glucosidase A (EC:3.2.1.58)
Alternative name(s):
Exo-1,3-beta-glucanase 1
Exo-1,3-beta-glucanase A
Gene namesi
Name:exgA
Synonyms:exg1
ORF Names:AFLA_028260
OrganismiAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Taxonomic identifieri332952 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000001875 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:AFLA_028260

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 14Sequence analysisAdd BLAST14
ChainiPRO_000039352915 – 405Probable glucan 1,3-beta-glucosidase AAdd BLAST391

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi280 ↔ 405By similarity
Disulfide bondi306 ↔ 332By similarity

Keywords - PTMi

Disulfide bond

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

STRINGi5059.CADAFLAP00002201

Structurei

3D structure databases

ProteinModelPortaliB8N151
SMRiB8N151
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

HOGENOMiHOG000114462
KOiK01210
OMAiEGAPGWD
OrthoDBiEOG092C22A6

Family and domain databases

InterProiView protein in InterPro
IPR001547 Glyco_hydro_5
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00150 Cellulase, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B8N151-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPLLLCIVP YCWSSRLDPR ASSFDYNGEK VRGVNLGGWL VLEPWITPSI
60 70 80 90 100
FDAAGAEAVD EWSLTKILGK EEAEARLSAH WKSFVSAGDF QRMADAGLNH
110 120 130 140 150
VRIPIGYWAL GPLEGDPYVD GQLEYLDKAV EWAGAAGLKV LIDLHGAPGS
160 170 180 190 200
QNGFDNSGRR GAIQWQQGDT VEQTLDAFDL LAERYLGSDT VAAIEAINEP
210 220 230 240 250
NIPGGVDQGK LQEYYGSVYG IVNKYNAGTS VVYGDGFLPV ESWNGFKTEG
260 270 280 290 300
SKVVMDTHHY HMFDNGLIAM DIDSHIDAVC QFAHQHLEAS DKPVIVGEWT
310 320 330 340 350
GAVTDCAKYL NGKGNGARYD GSYAADKAIG DCSSLATGFV SKLSDEERSD
360 370 380 390 400
MRRFIEAQLD AFELKSGWVF WTWKTEGAPG WDMSDLLEAG VFPTSPDDRE

FPKQC
Length:405
Mass (Da):44,373
Last modified:March 3, 2009 - v1
Checksum:iFC8D181C0A37A7C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ963473 Genomic DNA Translation: EED55554.1
RefSeqiXP_002374336.1, XM_002374295.1

Genome annotation databases

EnsemblFungiiEED55554; EED55554; AFLA_028260
GeneIDi7910329
KEGGiafv:AFLA_028260

Similar proteinsi

Entry informationi

Entry nameiEXGA_ASPFN
AccessioniPrimary (citable) accession number: B8N151
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 20, 2010
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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