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Protein

Glutamate decarboxylase

Gene

AFLA_077920

Organism
Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
ORF Names:AFLA_077920Imported
OrganismiAspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167)Imported
Taxonomic identifieri332952 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus
Proteomesi
  • UP000001875 Componenti: Unassembled WGS sequence

Organism-specific databases

EuPathDBiFungiDB:AFLA_077920.

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei290N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi5059.CADAFLAP00000574.

Structurei

3D structure databases

ProteinModelPortaliB8MXK5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiYTGQYED.
OrthoDBiEOG092C1P0W.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiView protein in InterPro
IPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_sub2.
PANTHERiPTHR43321. PTHR43321. 1 hit.
PfamiView protein in Pfam
PF00282. Pyridoxal_deC. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

B8MXK5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHLSRVKRG KQAQKPQQEQ DQGESAASPY VYGTHYATEE LPEHVMSEQE
60 70 80 90 100
MPADVAFRLI KDELSLDGNP LLNLASFVTT YMEDEAQNLM TDAMSKNFID
110 120 130 140 150
FEEYPQTAHI QNRCINMIAH LLNAPTTEGD GELDTIGTST IGSSEAIMLA
160 170 180 190 200
TLAMKKRWQN KRKAEGKDWT RPNIVMNSAV QVCWEKAARY FDVEEKYVYC
210 220 230 240 250
TDTRYVIDPK TAVDMVDENT IGICAIMGTT YTGQYEDVKA INDLLKAKNI
260 270 280 290 300
DCPIHVDAAS GGFVAPFVRP ELEWDFRLEK VVSINVSGHK YGLVYPGVGW
310 320 330 340 350
VFWRSPEYLP EELIFNVNYL GSNQATFTLN FSKGASHVIG QYYQLIRLGK
360 370 380 390 400
HGYRSIMQNL TKTSDYFADE LKKLGFLIMS DGNGRGLPLV AFRMKPDDDR
410 420 430 440 450
LYDEFALAHV LRQRGWIVPA YTMAPHSNQL KLMRVVLRED FTIHRCNILL
460 470 480 490 500
EDIKAALKSL QEMDAEMIQK YTLYVLDATN GVCKLTRTGT LGRTARRNCH
510 520 530 540
SNMHITKMRS TRCRVKLGRR MVYADFTSRR WVHSKNISCQ KAFTYRFQ
Length:548
Mass (Da):62,622
Last modified:March 3, 2009 - v1
Checksum:i8EC8DF3503D9BC57
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EQ963472 Genomic DNA. Translation: EED57097.1.
RefSeqiXP_002372709.1. XM_002372668.1.

Genome annotation databases

EnsemblFungiiEED57097; EED57097; AFLA_077920.
GeneIDi7913053.
KEGGiafv:AFLA_077920.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB8MXK5_ASPFN
AccessioniPrimary (citable) accession number: B8MXK5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 5, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported