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Protein
Submitted name:

Chemokine receptor 5

Gene

CCR5

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Chemokine receptor 5Imported
Gene namesi
Name:CCR5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei14 – 38HelicalSequence analysisAdd BLAST25
Transmembranei70 – 94HelicalSequence analysisAdd BLAST25
Transmembranei106 – 129HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiB8LFN8.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 147G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST147

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG106917.

Family and domain databases

InterProiView protein in InterPro
IPR002240. Chemokine_CCR5.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
PANTHERiPTHR10489:SF831. PTHR10489:SF831. 1 hit.
PfamiView protein in Pfam
PF00001. 7tm_1. 1 hit.
PRINTSiPR01110. CHEMOKINER5.
PR00237. GPCRRHODOPSN.
PROSITEiView protein in PROSITE
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.

Sequencei

Sequence statusi: Fragment.

B8LFN8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
AVVHAVFALK ARTVTFGVVT SVITWVVAVF ASLPGIIFTR SQKEGLHYTC
60 70 80 90 100
SSHFPYSQYQ FWKNFQTLKI VILGLVLPLL VMVICYSGIL KTLLRCRNEK
110 120 130 140
KRHRAVRLIF TIMIVYFLFW APYNIVLLLN TFQEFFGLNN CSSSNRL
Length:147
Mass (Da):16,927
Last modified:March 3, 2009 - v1
Checksum:i6E934C9A2BACC208
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei147Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF202087 Genomic DNA. Translation: ABU55681.1.
UniGeneiHs.450802.

Similar proteinsi

Entry informationi

Entry nameiB8LFN8_HUMAN
AccessioniPrimary (citable) accession number: B8LFN8
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: August 30, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.