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B8LFN8

- B8LFN8_HUMAN

UniProt

B8LFN8 - B8LFN8_HUMAN

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Protein
Submitted name:

Chemokine receptor 5

Gene

CCR5

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. C-C chemokine receptor activity Source: InterPro

GO - Biological processi

  1. chemotaxis Source: InterPro
  2. immune response Source: InterPro
  3. inflammatory response Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Chemokine receptor 5Imported
Gene namesi
Name:CCR5Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiB8LFN8.
ExpressionAtlasiB8LFN8. baseline and differential.

Interactioni

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG106917.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR002240. Chemokine_CCR5.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PANTHERiPTHR24227. PTHR24227. 1 hit.
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01110. CHEMOKINER5.
PR00237. GPCRRHODOPSN.
PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B8LFN8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
AVVHAVFALK ARTVTFGVVT SVITWVVAVF ASLPGIIFTR SQKEGLHYTC
60 70 80 90 100
SSHFPYSQYQ FWKNFQTLKI VILGLVLPLL VMVICYSGIL KTLLRCRNEK
110 120 130 140
KRHRAVRLIF TIMIVYFLFW APYNIVLLLN TFQEFFGLNN CSSSNRL
Length:147
Mass (Da):16,927
Last modified:March 3, 2009 - v1
Checksum:i6E934C9A2BACC208
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei147 – 1471Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF202087 Genomic DNA. Translation: ABU55681.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF202087 Genomic DNA. Translation: ABU55681.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi B8LFN8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG106917.

Miscellaneous databases

NextBioi 35481522.

Gene expression databases

Bgeei B8LFN8.
ExpressionAtlasi B8LFN8. baseline and differential.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR002240. Chemokine_CCR5.
IPR000355. Chemokine_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
PANTHERi PTHR24227. PTHR24227. 1 hit.
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR01110. CHEMOKINER5.
PR00237. GPCRRHODOPSN.
PROSITEi PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular characterization of chemokine receptor CCR5 gene in different ethnic populations of India."
    Saxena S.K., Singh M., Mishra N., Bhatnager I., Singh L.
    Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: CCMB-SKS-1Imported.

Entry informationi

Entry nameiB8LFN8_HUMAN
AccessioniPrimary (citable) accession number: B8LFN8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 26, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.