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B8LFN8

- B8LFN8_HUMAN

UniProt

B8LFN8 - B8LFN8_HUMAN

Protein
Submitted name:

Chemokine receptor 5

Gene

CCR5

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. C-C chemokine receptor activity Source: InterPro

    GO - Biological processi

    1. chemotaxis Source: InterPro
    2. immune response Source: InterPro
    3. inflammatory response Source: InterPro

    Keywords - Molecular functioni

    G-protein coupled receptorSAAS annotation, Receptor, Transducer

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Chemokine receptor 5Imported
    Gene namesi
    Name:CCR5Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiB8LFN8.
    BgeeiB8LFN8.

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG106917.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR002240. Chemokine_CCR5.
    IPR000355. Chemokine_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view]
    PANTHERiPTHR24227. PTHR24227. 1 hit.
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR01110. CHEMOKINER5.
    PR00237. GPCRRHODOPSN.
    PROSITEiPS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    B8LFN8-1 [UniParc]FASTAAdd to Basket

    « Hide

    AVVHAVFALK ARTVTFGVVT SVITWVVAVF ASLPGIIFTR SQKEGLHYTC    50
    SSHFPYSQYQ FWKNFQTLKI VILGLVLPLL VMVICYSGIL KTLLRCRNEK 100
    KRHRAVRLIF TIMIVYFLFW APYNIVLLLN TFQEFFGLNN CSSSNRL 147
    Length:147
    Mass (Da):16,927
    Last modified:March 3, 2009 - v1
    Checksum:i6E934C9A2BACC208
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported
    Non-terminal residuei147 – 1471Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EF202087 Genomic DNA. Translation: ABU55681.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    EF202087 Genomic DNA. Translation: ABU55681.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG106917.

    Miscellaneous databases

    NextBioi 35481522.

    Gene expression databases

    ArrayExpressi B8LFN8.
    Bgeei B8LFN8.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR002240. Chemokine_CCR5.
    IPR000355. Chemokine_rcpt.
    IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    [Graphical view ]
    PANTHERi PTHR24227. PTHR24227. 1 hit.
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR01110. CHEMOKINER5.
    PR00237. GPCRRHODOPSN.
    PROSITEi PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Molecular characterization of chemokine receptor CCR5 gene in different ethnic populations of India."
      Saxena S.K., Singh M., Mishra N., Bhatnager I., Singh L.
      Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: CCMB-SKS-1Imported.

    Entry informationi

    Entry nameiB8LFN8_HUMAN
    AccessioniPrimary (citable) accession number: B8LFN8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.