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Protein

UDP-glucuronosyltransferase

Gene

ugt2a4

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucuronosyltransferaseUniRule annotation (EC:2.4.1.17UniRule annotation)
Gene namesi
Name:ugt2a4Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 5

Organism-specific databases

ZFINiZDB-GENE-080721-23. ugt2a4.

Subcellular locationi

  • Membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei12 – 3019HelicalUniRule annotationAdd
BLAST
Transmembranei213 – 23119HelicalUniRule annotationAdd
BLAST
Transmembranei492 – 51524HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiB8JMA7.

Family & Domainsi

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000118949.
HOGENOMiHOG000220831.
HOVERGENiHBG004033.
KOiK00699.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8JMA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKCLLKPSP LVLIFIFSFT HAGNVLVLPG EYSHWQNMRN VVDELLNRNH
60 70 80 90 100
TVTVLVCSAS PTINFTQQER FQYLVFEVPL SAQELDGASE ELIHIWTQHP
110 120 130 140 150
SPNRLQTALQ IIELLGRVRV MHRAMCDSML RNDALIAQLS ALKFDVLFND
160 170 180 190 200
PMFMCADLLA EMLGLPLVLS VRISPGFCLE RMCGQMPAPP SFVPITQTVL
210 220 230 240 250
TDRMCFMERV QNMIANIVFS VSFYIVAWIS LDSYYTDVLG KPTTMCETMG
260 270 280 290 300
KADIWLIRTY WDFEYPRPFP PNFKFVGGLH CKPAKPLSKE MEEFVQSSGD
310 320 330 340 350
HGVVVFSLGS MIKNLTSERA NTIAAALGQI PQKVVWRYSG KTPETLAPNT
360 370 380 390 400
KIYDWIPQND LLGHPKTKAF ITHGGTNGLY EAIYHGVPMV GLPLFADQPD
410 420 430 440 450
NLLHMKTKGA AVVLDINTLE SKDLVDALKT VLNNPSYKES IMRLSRIHHD
460 470 480 490 500
QPMKPLDQAV YWIEFVMRNK GAKHLRVQAH ELSWYQYHCL DVAAFLLSIA
510 520 530
ALITFLWVKA CCFLFRRCVR KTRPERKTQK SKNE
Length:534
Mass (Da):60,745
Last modified:March 3, 2009 - v1
Checksum:iFA3491FADCCE4CF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR753888 Genomic DNA. No translation available.
CU571335 Genomic DNA. No translation available.
RefSeqiNP_001018306.2. NM_001020470.2.
UniGeneiDr.77425.

Genome annotation databases

EnsembliENSDART00000127782; ENSDARP00000109851; ENSDARG00000051940.
GeneIDi553952.
KEGGidre:553952.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR753888 Genomic DNA. No translation available.
CU571335 Genomic DNA. No translation available.
RefSeqiNP_001018306.2. NM_001020470.2.
UniGeneiDr.77425.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000127782; ENSDARP00000109851; ENSDARG00000051940.
GeneIDi553952.
KEGGidre:553952.

Organism-specific databases

CTDi574537.
ZFINiZDB-GENE-080721-23. ugt2a4.

Phylogenomic databases

GeneTreeiENSGT00760000118949.
HOGENOMiHOG000220831.
HOVERGENiHBG004033.
KOiK00699.

Gene expression databases

BgeeiB8JMA7.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G., Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  2. Ensembl
    Submitted (MAY-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiB8JMA7_DANRE
AccessioniPrimary (citable) accession number: B8JMA7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 8, 2016
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.