ugt2a4

Functionⁱ

Catalytic activityⁱ

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.UniRule annotation

GO - Molecular functionⁱ

glucuronosyltransferase activity Source: UniProtKB-EC

Complete GO annotation...

GO - Biological processⁱ

metabolic process Source: InterPro

Complete GO annotation...

Keywordsⁱ

Molecular function	GlycosyltransferaseUniRule annotation, Transferase

Molecular function

GlycosyltransferaseUniRule annotation, Transferase

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GT1. Glycosyltransferase Family 1.

CAZyⁱ

GT1. Glycosyltransferase Family 1.

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: UDP-glucuronosyltransferaseUniRule annotation (EC:2.4.1.17UniRule annotation)
Gene namesⁱ	Name:ugt2a4Imported Synonyms:ugt2a1Imported
Organismⁱ	Danio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifierⁱ	7955 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Osteoglossocephalai › Clupeocephala › Otomorpha › Ostariophysi › Otophysi › Cypriniphysae › Cypriniformes › Cyprinoidea › Cyprinidae › Danio
Proteomesⁱ	UP000000437 Componentⁱ: Chromosome 5

Organism-specific databases

ZFINⁱ	ZDB-GENE-080721-20. ugt2a1. ZDB-GENE-080721-23. ugt2a4.

ZFINⁱ

ZDB-GENE-080721-20. ugt2a1.
ZDB-GENE-080721-23. ugt2a4.

Subcellular locationⁱ

Membrane
UniRule annotation
Automatic assertion according to rulesⁱ
- RuleBase:RU362059
; Single-pass membrane protein
UniRule annotation
Automatic assertion according to rulesⁱ
- RuleBase:RU362059

Topology

Feature key	Position(s)	DescriptionActions	Length
Transmembraneⁱ	12 – 30	HelicalUniRule annotationAdd BLAST	19
Transmembraneⁱ	213 – 231	HelicalUniRule annotationAdd BLAST	19
Transmembraneⁱ	492 – 515	HelicalUniRule annotationAdd BLAST	24

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-UniRule

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	B8JMA7.

PeptideAtlasⁱ

B8JMA7.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSDARG00000051940.
ExpressionAtlasⁱ	B8JMA7. baseline.

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the UDP-glycosyltransferase family.UniRule annotation

Keywords - Domainⁱ

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118949.
HOGENOMⁱ	HOG000220831.
HOVERGENⁱ	HBG004033.
KEGG Orthology (KO) More...KOⁱ	K00699.

Family and domain databases

InterProⁱ	View protein in InterPro IPR002213. UDP_glucos_trans.
PANTHERⁱ	PTHR11926. PTHR11926. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00201. UDPGT. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00375. UDPGT. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

B8JMA7-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MMKCLLKPSP LVLIFIFSFT HAGNVLVLPG EYSHWQNMRN VVDELLNRNH 
        60         70         80         90        100
TVTVLVCSAS PTINFTQQER FQYLVFEVPL SAQELDGASE ELIHIWTQHP 
       110        120        130        140        150
SPNRLQTALQ IIELLGRVRV MHRAMCDSML RNDALIAQLS ALKFDVLFND 
       160        170        180        190        200
PMFMCADLLA EMLGLPLVLS VRISPGFCLE RMCGQMPAPP SFVPITQTVL 
       210        220        230        240        250
TDRMCFMERV QNMIANIVFS VSFYIVAWIS LDSYYTDVLG KPTTMCETMG 
       260        270        280        290        300
KADIWLIRTY WDFEYPRPFP PNFKFVGGLH CKPAKPLSKE MEEFVQSSGD 
       310        320        330        340        350
HGVVVFSLGS MIKNLTSERA NTIAAALGQI PQKVVWRYSG KTPETLAPNT 
       360        370        380        390        400
KIYDWIPQND LLGHPKTKAF ITHGGTNGLY EAIYHGVPMV GLPLFADQPD 
       410        420        430        440        450
NLLHMKTKGA AVVLDINTLE SKDLVDALKT VLNNPSYKES IMRLSRIHHD 
       460        470        480        490        500
QPMKPLDQAV YWIEFVMRNK GAKHLRVQAH ELSWYQYHCL DVAAFLLSIA 
       510        520        530 
ALITFLWVKA CCFLFRRCVR KTRPERKTQK SKNE

Length:534

Mass (Da):60,745

Last modified:March 3, 2009 - v1

Checksum:ⁱFA3491FADCCE4CF8

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CR753888 Genomic DNA. No translation available. CU571335 Genomic DNA. No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001018306.2. NM_001020470.2.
UniGeneⁱ	Dr.77425.

Genome annotation databases

Ensemblⁱ	ENSDART00000127782; ENSDARP00000109851; ENSDARG00000051940.
GeneIDⁱ	553952.
KEGGⁱ	dre:553952.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	CR753888 Genomic DNA. No translation available. CU571335 Genomic DNA. No translation available.
NCBI Reference Sequences More...RefSeqⁱ	NP_001018306.2. NM_001020470.2.
UniGeneⁱ	Dr.77425.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein family/group databases

Carbohydrate-Active enZymes More...CAZyⁱ	GT1. Glycosyltransferase Family 1.

CAZyⁱ

GT1. Glycosyltransferase Family 1.

Proteomic databases

PeptideAtlas More...PeptideAtlasⁱ	B8JMA7.

PeptideAtlasⁱ

B8JMA7.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSDART00000127782; ENSDARP00000109851; ENSDARG00000051940.
GeneIDⁱ	553952.
KEGGⁱ	dre:553952.

Organism-specific databases

CTDⁱ	574537.
ZFINⁱ	ZDB-GENE-080721-20. ugt2a1. ZDB-GENE-080721-23. ugt2a4.

Phylogenomic databases

Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118949.
HOGENOMⁱ	HOG000220831.
HOVERGENⁱ	HBG004033.
KEGG Orthology (KO) More...KOⁱ	K00699.

Gene expression databases

Bgeeⁱ	ENSDARG00000051940.
ExpressionAtlasⁱ	B8JMA7. baseline.

Family and domain databases

InterProⁱ	View protein in InterPro IPR002213. UDP_glucos_trans.
PANTHERⁱ	PTHR11926. PTHR11926. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00201. UDPGT. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00375. UDPGT. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	B8JMA7_DANRE
Accessionⁱ	B8JMA7Primary (citable) accession number: B8JMA7
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 3, 2009
	Last sequence update:	March 3, 2009
	Last modified:	July 5, 2017
	This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - B8JMA7 (B8JMA7_DANRE)

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UDP-glucuronosyltransferase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein family/group databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Caution

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ