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Protein

UDP-glucuronosyltransferase

Gene

ugt2a4

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseUniRule annotation, Transferase

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucuronosyltransferaseUniRule annotation (EC:2.4.1.17UniRule annotation)
Gene namesi
Name:ugt2a4Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 5

Organism-specific databases

ZFINiZDB-GENE-080721-23. ugt2a4.

Subcellular locationi

  • Membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 30HelicalUniRule annotationAdd BLAST19
Transmembranei213 – 231HelicalUniRule annotationAdd BLAST19
Transmembranei492 – 515HelicalUniRule annotationAdd BLAST24

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiB8JMA7.

Expressioni

Gene expression databases

BgeeiENSDARG00000051940.
ExpressionAtlasiB8JMA7. baseline.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini355 – 398UDPGTInterPro annotationAdd BLAST44

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000118949.
HOGENOMiHOG000220831.
HOVERGENiHBG004033.
KOiK00699.

Family and domain databases

InterProiView protein in InterPro
IPR002213. UDP_glucos_trans.
IPR035595. UDP_glycos_trans_CS.
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiView protein in Pfam
PF00201. UDPGT. 1 hit.
PROSITEiView protein in PROSITE
PS00375. UDPGT. 1 hit.

Sequencei

Sequence statusi: Complete.

B8JMA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKCLLKPSP LVLIFIFSFT HAGNVLVLPG EYSHWQNMRN VVDELLNRNH
60 70 80 90 100
TVTVLVCSAS PTINFTQQER FQYLVFEVPL SAQELDGASE ELIHIWTQHP
110 120 130 140 150
SPNRLQTALQ IIELLGRVRV MHRAMCDSML RNDALIAQLS ALKFDVLFND
160 170 180 190 200
PMFMCADLLA EMLGLPLVLS VRISPGFCLE RMCGQMPAPP SFVPITQTVL
210 220 230 240 250
TDRMCFMERV QNMIANIVFS VSFYIVAWIS LDSYYTDVLG KPTTMCETMG
260 270 280 290 300
KADIWLIRTY WDFEYPRPFP PNFKFVGGLH CKPAKPLSKE MEEFVQSSGD
310 320 330 340 350
HGVVVFSLGS MIKNLTSERA NTIAAALGQI PQKVVWRYSG KTPETLAPNT
360 370 380 390 400
KIYDWIPQND LLGHPKTKAF ITHGGTNGLY EAIYHGVPMV GLPLFADQPD
410 420 430 440 450
NLLHMKTKGA AVVLDINTLE SKDLVDALKT VLNNPSYKES IMRLSRIHHD
460 470 480 490 500
QPMKPLDQAV YWIEFVMRNK GAKHLRVQAH ELSWYQYHCL DVAAFLLSIA
510 520 530
ALITFLWVKA CCFLFRRCVR KTRPERKTQK SKNE
Length:534
Mass (Da):60,745
Last modified:March 3, 2009 - v1
Checksum:iFA3491FADCCE4CF8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR753888 Genomic DNA. No translation available.
CU571335 Genomic DNA. No translation available.
RefSeqiNP_001018306.2. NM_001020470.2.
UniGeneiDr.77425.

Genome annotation databases

EnsembliENSDART00000127782; ENSDARP00000109851; ENSDARG00000051940.
GeneIDi553952.
KEGGidre:553952.

Similar proteinsi

Entry informationi

Entry nameiB8JMA7_DANRE
AccessioniPrimary (citable) accession number: B8JMA7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: August 30, 2017
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported