B8JLJ1 (B8JLJ1_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Uncharacterized protein Ensembl ENSDARP00000118353

Gene names

Name:	ntrk3a ZFIN ZDB-GENE-010126-3
Synonyms:	ntrk2a Ensembl ENSDARP00000118353

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome] Ensembl ENSDARP00000118353

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	392 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. SAAS SAAS008266
Sequence similarities	Contains 1 protein kinase domain. SAAS SAAS008266
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSDARP00000118353

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS008266 Nucleotide-binding
Molecular function	Kinase Transferase Tyrosine-protein kinase SAAS SAAS008266
PTM	Phosphoprotein SAAS SAAS002011
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transmembrane receptor protein tyrosine kinase signaling pathway Inferred from electronic annotation. Source: InterPro
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW transmembrane receptor protein tyrosine kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	Ensembl ENSDARP00000118353

Sequences

	Sequence		Length	Mass (Da)
	B8JLJ1 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: C6A8BC6996666E69	FASTA	392	44,281
	10 20 30 40 50 60 VYVVVGIAAI TFTGFVLMLV ILKFGRNSKF GIKGPSSVIS NDDDSASPLH HVSNGSNTPS 70 80 90 100 110 120 SSDMNADAVI IGMTKIPVIE NPQYFRSTSS LLKSDTFVQH IKRHNIVLKR ELGEGAFGKV 130 140 150 160 170 180 FLAECYNLSA DQEKILVAVK TLKEASENAR KDFHREAELL TNLQHEHIVT FYGVCVESDP 190 200 210 220 230 240 LIMVFEYMMH GDLNKFLRAH GPDAVLMSDG QIQQQAELTQ SQMLHIAQQI AAGMVYLASQ 250 260 270 280 290 300 HFVHRDLATR NCLVGENLLV KIGDFGMSRD VYSTDYYRVG GHTMLPIRWM PPESIMYRKF 310 320 330 340 350 360 TTESDVWSLG VVLWEIFTYG KQPWYQLSNN EVIECITQGR VLQRPRTCPK EVYDLMLGCW 370 380 390 QREPHTRLNI KEIHNLLLNL AKASPVYLDI LG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000118353.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000118353.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU468685 Genomic DNA. No translation available. CU682767 Genomic DNA. No translation available.
IPI	IPI00960840.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000131732; ENSDARP00000118353; ENSDARG00000059897.
Organism-specific databases
ZFIN	ZDB-GENE-010126-1. ntrk2a.
Phylogenomic databases
eggNOG	COG0515.
GeneTree	ENSGT00700000104172.
HOGENOM	HOG000264255.
HOVERGEN	HBG056735.
OMA	HERVIKL.
OrthoDB	EOG4255S6.
Gene expression databases
ArrayExpress	B8JLJ1.
Family and domain databases
InterPro	IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. IPR008266. Tyr_kinase_AS. IPR020635. Tyr_kinase_cat_dom. IPR002011. Tyr_kinase_rcpt_2_CS. [Graphical view]
Pfam	PF07714. Pkinase_Tyr. 1 hit. [Graphical view]
PRINTS	PR00109. TYRKINASE.
SMART	SM00219. TyrKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00109. PROTEIN_KINASE_TYR. 1 hit. PS00239. RECEPTOR_TYR_KIN_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8JLJ1_DANRE

Accession

Primary (citable) accession number: B8JLJ1

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)