B8JKD7 (B8JKD7_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA-directed RNA polymerase RuleBase RU000431
EC=2.7.7.6 RuleBase RU000431

Gene names

Name:	DKEY-18N13.2 EMBL CAX13206.1
Synonyms:	polr1b Ensembl ENSDARP00000100185
ORF Names:	DKEY-18N13.2-001 EMBL CAX13206.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL CAX13206.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	1132 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). RuleBase RU000431
Sequence similarities	Belongs to the RNA polymerase beta chain family. RuleBase RU000434

Ontologies

Keywords
Biological process	Transcription
Cellular component	DNA-directed RNA polymerase RuleBase RU000431
Molecular function	Nucleotidyltransferase RuleBase RU000431 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	nucleus Inferred from electronic annotation. Source: InterPro
Molecular function	DNA binding Inferred from electronic annotation. Source: InterPro DNA-directed RNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW ribonucleoside binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8JKD7 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: A329BA318FA2AA93	FASTA	1,132	127,612
	10 20 30 40 50 60 MDLSKWCNLK TEPSLKHLTE AGFGVPKEKQ SVPVQELVKA HIESFDQAVT DGLCRVVEAI 70 80 90 100 110 120 PPMEFLYKGD RISLSFVEAI IHTPSVSKGG ISRDLRVFPA ECRGRRCTYR AKLVADVSWS 130 140 150 160 170 180 VNGVPKGIIK QSLGQMPIMV KSKLCNLHGL SPKELLEHHE EAEEMGGYFI VNGIEKVIRL 190 200 210 220 230 240 LIMPRRNYPI AVSRPKFKSR GQGYTQYAIS MRCVKEEHTA INMNLHYLDN GTVMVNFIYR 250 260 270 280 290 300 KELFFLPLGF ALKALVDYSD YQIYQELIKG REDNSFYKSC VSEMLRIVMD QGCTTKIKVL 310 320 330 340 350 360 NYLGERFRVK LNLPEWFTHE QCAHFLLDEC LCIHLKTDVE KFYMLCLMTR KLFSFAKQEC 370 380 390 400 410 420 MEENPDSPMF HEVLTPGQLY LMFLKEKMEG WLVSVKLALE KKPQRVGGLT PDSMTKLFNM 430 440 450 460 470 480 GTDLTKAFEY LLATGNLMSK TGLGMLQNSG LCVVADKLNF IRYLSHFRCV HRGAAFAKMR 490 500 510 520 530 540 TTTVRKLLPE SWGFLCPVHT PDGEPCGLMN HMTAHCEIVA PVYPTSTLPG LLCSLGVNAA 550 560 570 580 590 600 DGNPGQAYSD CYPVILDGAM IGWVEKEVAP SVIESLRRFK VLGEKKVPPW TEIVLVPQTG 610 620 630 640 650 660 KASLYPGLYL FTTPCRMVRT VRNLSLGKQE LIGIFEQVYL NVGIFEKEIE DGVTTHQELF 670 680 690 700 710 720 PHSMLSVVAE FIPFSDHNQS PRNMYQCQMS KQTMGFPLHS YQYRSDNKLY RLQTPQSPLV 730 740 750 760 770 780 RPAMYDHYDV DNYPIGTNAI VAVISYTGYD MEDAMIVNKS SWERGFAHGS VYKTEIIDLS 790 800 810 820 830 840 EKVKGDDSIV FGVKPGDPKV MGKLDADGLP FIGSVLKYGD PFYGYISLNT GQSHVYFYKY 850 860 870 880 890 900 QESCVVDNIK VCSNETGTGR FKRICVTSRV PRNPTIGDKF ASRHGQKGIL SRLWPAEDMP 910 920 930 940 950 960 FTESGMSPDI LFNPHGFPSR MTIGMLIESM AGKSASLHGL CHDATPFTFS EENSALEHFG 970 980 990 1000 1010 1020 ELLKAAGYNY YGTERLYSGL SGLELEADIF IGVVYYQRLR HMVSDKFQVR TTGARDKVTN 1030 1040 1050 1060 1070 1080 QPMGGRNVQG GIRFGEMERD ALLAHGTSFL LHDRLFNCSD RSVAQVCMDC GSLLSPLLEK 1090 1100 1110 1120 1130 PPPNWSATRH RKTICLLCNK SDSIETVSVP YVFKYFVAEL AAMNIKIKLD VK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Clark S. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000100185.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000100185.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT583720 Genomic DNA. Translation: CAX13206.1.
IPI	IPI00859868.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B8JKD7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000114741; ENSDARP00000100185; ENSDARG00000077469.
Organism-specific databases
ZFIN	ZDB-GENE-040426-1598. polr1b.
Phylogenomic databases
HOVERGEN	HBG017742.
OMA	SHFRAIH.
Gene expression databases
Bgee	B8JKD7.
Family and domain databases
InterPro	IPR015712. DNA-dir_RNA_pol_su2. IPR007120. DNA-dir_RNA_pol_su2_6. IPR007121. RNA_pol_bsu_CS. IPR007644. RNA_pol_bsu_protrusion. IPR009674. RNA_pol_Rpa2-specific. IPR007642. RNA_pol_Rpb2_2. IPR007645. RNA_pol_Rpb2_3. IPR007641. RNA_pol_Rpb2_7. [Graphical view]
Gene3D	G3DSA:2.40.270.10. G3DSA:2.40.270.10. 2 hits.
PANTHER	PTHR20856. RNA_pol_I_sub2. 1 hit.
Pfam	PF06883. RNA_pol_Rpa2_4. 1 hit. PF04563. RNA_pol_Rpb2_1. 1 hit. PF04561. RNA_pol_Rpb2_2. 1 hit. PF04565. RNA_pol_Rpb2_3. 1 hit. PF00562. RNA_pol_Rpb2_6. 1 hit. PF04560. RNA_pol_Rpb2_7. 1 hit. [Graphical view]
PROSITE	PS01166. RNA_POL_BETA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8JKD7_DANRE

Accession

Primary (citable) accession number: B8JKD7

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)