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B8JK56

- B8JK56_MOUSE

UniProt

B8JK56 - B8JK56_MOUSE

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Protein
Submitted name:

Adenylate cyclase type 3

Gene
Adcy3
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. adenylate cyclase activity Source: MGI
  2. nucleotide binding Source: UniProtKB-KW
  3. protein binding Source: MGI

GO - Biological processi

  1. activation of adenylate cyclase activity Source: MGI
  2. cAMP biosynthetic process Source: MGI
  3. intracellular signal transduction Source: InterPro
  4. sensory perception of smell Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotations

Keywords - Ligandi

Nucleotide-bindingSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylate cyclase type 3Imported
Gene namesi
Name:Adcy3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 12

Organism-specific databases

MGIiMGI:99675. Adcy3.

Subcellular locationi

GO - Cellular componenti

  1. cilium Source: MGI
  2. integral component of membrane Source: UniProtKB-KW
  3. plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00750000117304.
HOVERGENiHBG050458.
KOiK08043.
TreeFamiTF313845.

Family and domain databases

Gene3Di3.30.70.1230. 2 hits.
InterProiIPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
[Graphical view]
PfamiPF00211. Guanylate_cyc. 2 hits.
[Graphical view]
SMARTiSM00044. CYCc. 2 hits.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 2 hits.
PROSITEiPS00452. GUANYLATE_CYCLASE_1. 2 hits.
PS50125. GUANYLATE_CYCLASE_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8JK56-1 [UniParc]FASTAAdd to Basket

« Hide

MPRNQGFSDP EYSAEYSAEY SVSLPSDPDR GVGRTHEISV RNSGSCLCLP     50
RFMRLTFVPE SLENLYQTYF KRQRHETLLV LVVFAALFDC YVVVMCAVVF 100
SSDKLAPLMV AGFGLVLDII LFVLCKKGLL PDRVSRKVVP YLLWLLISAQ 150
IFSYLGLNFS RAHAASDTVG WQAFFVFSFF ITLPLSLSPI VIISVVSCVV 200
HTLVLGVTVA QQQQDELEGM QLLREILANV FLYLCAIIVG IMSYYMADRK 250
HRKAFLEARQ SLEVKMNLEE QSQQQENLML SILPKHVADE MLKDMKKDES 300
QKDQQQFNTM YMYRHENVSI LFADIVGFTQ LSSACSAQEL VKLLNELFAR 350
FDKLAAKYHQ LRIKILGDCY YCICGLPDYR EDHAVCSILM GLAMVEAISY 400
VREKTKTGVD MRVGVHTGTV LGGVLGQKRW QYDVWSTDVT VANKMEAGGI 450
PGRVHISQST MDCLKGEFDV EPGDGGSRCD YLDEKGIETY LIIASKPEVK 500
KTAQNGLNGS AVPNGAPASS KPSSPALIET KEPNGSAHAS GSTSEEAEEQ 550
EAQADNPSFP NPRRRLRLQD LADRVVDASE DEHELNQLLN EALLERESAQ 600
VVKKRNTFLL TMRFMDPEME TRYSVEKEKQ SGAAFSCSCV VLFCTAMVEI 650
LIDPWLMTNY VTFVVGEVLL LILTICSMAA IFPRSFPKKL VAFSSWIDRT 700
RWARNTWAML AIFILVMANV VDMLSCLQYY MGPYNMTAGM ELDGGCMENP 750
KYYNYVAVLS LIATIMLVQV SHMVKLTLML LVTGAVTALN LYAWCPVFDE 800
YDHKRFQEKD SPMVALEKMQ VLATPGLNGT DRLPLVPSKY SMTVMMFVMM 850
LSFYYFSRHV EKLARTLFLW KIEVHDQKER VYEMRRWNEA LVTNMLPEHV 900
ARHFLGSKKR DEELYSQSYD EIGVMFASLP NFADFYTEES INNGGIECLR 950
FLNEIISDFD SLLDNPKFRV ITKIKTIGST YMAASGVTPD VNTNGFTSSS 1000
KEEKSDKERW QHLADLADFA LAMKDTLTNI NNQSFNNFML RIGMNKGGVL 1050
AGVIGARKPH YDIWGNTVNV ASRMESTGVM GNIQVVEETQ VILREYGFRF 1100
VRRGPIFVKG KGELLTFFLK GRDRPAAFPN GSSVTLPHQV VDNP 1144
Length:1,144
Mass (Da):128,998
Last modified:March 3, 2009 - v1
Checksum:i989F69F858CEC87C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT572999 Genomic DNA. No translation available.
RefSeqiNP_001153008.1. NM_001159536.1.
NP_001153009.1. NM_001159537.1.
UniGeneiMm.489807.

Genome annotation databases

EnsembliENSMUST00000124505; ENSMUSP00000122073; ENSMUSG00000020654.
ENSMUST00000152065; ENSMUSP00000115644; ENSMUSG00000020654.
GeneIDi104111.
KEGGimmu:104111.
UCSCiuc007mxk.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CT572999 Genomic DNA. No translation available.
RefSeqi NP_001153008.1. NM_001159536.1.
NP_001153009.1. NM_001159537.1.
UniGenei Mm.489807.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000124505 ; ENSMUSP00000122073 ; ENSMUSG00000020654 .
ENSMUST00000152065 ; ENSMUSP00000115644 ; ENSMUSG00000020654 .
GeneIDi 104111.
KEGGi mmu:104111.
UCSCi uc007mxk.2. mouse.

Organism-specific databases

CTDi 109.
MGIi MGI:99675. Adcy3.

Phylogenomic databases

GeneTreei ENSGT00750000117304.
HOVERGENi HBG050458.
KOi K08043.
TreeFami TF313845.

Miscellaneous databases

ChiTaRSi ADCY3. mouse.
NextBioi 356544.
SOURCEi Search...

Family and domain databases

Gene3Di 3.30.70.1230. 2 hits.
InterProi IPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
[Graphical view ]
Pfami PF00211. Guanylate_cyc. 2 hits.
[Graphical view ]
SMARTi SM00044. CYCc. 2 hits.
[Graphical view ]
SUPFAMi SSF55073. SSF55073. 2 hits.
PROSITEi PS00452. GUANYLATE_CYCLASE_1. 2 hits.
PS50125. GUANYLATE_CYCLASE_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB8JK56_MOUSE
AccessioniPrimary (citable) accession number: B8JK56
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 11, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi