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B8JK56

- B8JK56_MOUSE

UniProt

B8JK56 - B8JK56_MOUSE

Protein
Submitted name:

Adenylate cyclase type 3

Gene

Adcy3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. adenylate cyclase activity Source: MGI
    2. nucleotide binding Source: UniProtKB-KW
    3. protein binding Source: MGI

    GO - Biological processi

    1. activation of adenylate cyclase activity Source: MGI
    2. cAMP biosynthetic process Source: MGI
    3. intracellular signal transduction Source: InterPro
    4. sensory perception of smell Source: MGI

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Nucleotide-bindingSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Adenylate cyclase type 3Imported
    Gene namesi
    Name:Adcy3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 12

    Organism-specific databases

    MGIiMGI:99675. Adcy3.

    Subcellular locationi

    GO - Cellular componenti

    1. cilium Source: MGI
    2. integral component of membrane Source: UniProtKB-KW
    3. plasma membrane Source: MGI

    Keywords - Cellular componenti

    Membrane

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00750000117304.
    HOVERGENiHBG050458.
    KOiK08043.
    TreeFamiTF313845.

    Family and domain databases

    Gene3Di3.30.70.1230. 2 hits.
    InterProiIPR001054. A/G_cyclase.
    IPR018297. A/G_cyclase_CS.
    [Graphical view]
    PfamiPF00211. Guanylate_cyc. 2 hits.
    [Graphical view]
    SMARTiSM00044. CYCc. 2 hits.
    [Graphical view]
    SUPFAMiSSF55073. SSF55073. 2 hits.
    PROSITEiPS00452. GUANYLATE_CYCLASE_1. 2 hits.
    PS50125. GUANYLATE_CYCLASE_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8JK56-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPRNQGFSDP EYSAEYSAEY SVSLPSDPDR GVGRTHEISV RNSGSCLCLP     50
    RFMRLTFVPE SLENLYQTYF KRQRHETLLV LVVFAALFDC YVVVMCAVVF 100
    SSDKLAPLMV AGFGLVLDII LFVLCKKGLL PDRVSRKVVP YLLWLLISAQ 150
    IFSYLGLNFS RAHAASDTVG WQAFFVFSFF ITLPLSLSPI VIISVVSCVV 200
    HTLVLGVTVA QQQQDELEGM QLLREILANV FLYLCAIIVG IMSYYMADRK 250
    HRKAFLEARQ SLEVKMNLEE QSQQQENLML SILPKHVADE MLKDMKKDES 300
    QKDQQQFNTM YMYRHENVSI LFADIVGFTQ LSSACSAQEL VKLLNELFAR 350
    FDKLAAKYHQ LRIKILGDCY YCICGLPDYR EDHAVCSILM GLAMVEAISY 400
    VREKTKTGVD MRVGVHTGTV LGGVLGQKRW QYDVWSTDVT VANKMEAGGI 450
    PGRVHISQST MDCLKGEFDV EPGDGGSRCD YLDEKGIETY LIIASKPEVK 500
    KTAQNGLNGS AVPNGAPASS KPSSPALIET KEPNGSAHAS GSTSEEAEEQ 550
    EAQADNPSFP NPRRRLRLQD LADRVVDASE DEHELNQLLN EALLERESAQ 600
    VVKKRNTFLL TMRFMDPEME TRYSVEKEKQ SGAAFSCSCV VLFCTAMVEI 650
    LIDPWLMTNY VTFVVGEVLL LILTICSMAA IFPRSFPKKL VAFSSWIDRT 700
    RWARNTWAML AIFILVMANV VDMLSCLQYY MGPYNMTAGM ELDGGCMENP 750
    KYYNYVAVLS LIATIMLVQV SHMVKLTLML LVTGAVTALN LYAWCPVFDE 800
    YDHKRFQEKD SPMVALEKMQ VLATPGLNGT DRLPLVPSKY SMTVMMFVMM 850
    LSFYYFSRHV EKLARTLFLW KIEVHDQKER VYEMRRWNEA LVTNMLPEHV 900
    ARHFLGSKKR DEELYSQSYD EIGVMFASLP NFADFYTEES INNGGIECLR 950
    FLNEIISDFD SLLDNPKFRV ITKIKTIGST YMAASGVTPD VNTNGFTSSS 1000
    KEEKSDKERW QHLADLADFA LAMKDTLTNI NNQSFNNFML RIGMNKGGVL 1050
    AGVIGARKPH YDIWGNTVNV ASRMESTGVM GNIQVVEETQ VILREYGFRF 1100
    VRRGPIFVKG KGELLTFFLK GRDRPAAFPN GSSVTLPHQV VDNP 1144
    Length:1,144
    Mass (Da):128,998
    Last modified:March 3, 2009 - v1
    Checksum:i989F69F858CEC87C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT572999 Genomic DNA. No translation available.
    RefSeqiNP_001153008.1. NM_001159536.1.
    NP_001153009.1. NM_001159537.1.
    UniGeneiMm.489807.

    Genome annotation databases

    EnsembliENSMUST00000124505; ENSMUSP00000122073; ENSMUSG00000020654.
    ENSMUST00000152065; ENSMUSP00000115644; ENSMUSG00000020654.
    GeneIDi104111.
    KEGGimmu:104111.
    UCSCiuc007mxk.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT572999 Genomic DNA. No translation available.
    RefSeqi NP_001153008.1. NM_001159536.1.
    NP_001153009.1. NM_001159537.1.
    UniGenei Mm.489807.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000124505 ; ENSMUSP00000122073 ; ENSMUSG00000020654 .
    ENSMUST00000152065 ; ENSMUSP00000115644 ; ENSMUSG00000020654 .
    GeneIDi 104111.
    KEGGi mmu:104111.
    UCSCi uc007mxk.2. mouse.

    Organism-specific databases

    CTDi 109.
    MGIi MGI:99675. Adcy3.

    Phylogenomic databases

    GeneTreei ENSGT00750000117304.
    HOVERGENi HBG050458.
    KOi K08043.
    TreeFami TF313845.

    Miscellaneous databases

    ChiTaRSi ADCY3. mouse.
    NextBioi 356544.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 3.30.70.1230. 2 hits.
    InterProi IPR001054. A/G_cyclase.
    IPR018297. A/G_cyclase_CS.
    [Graphical view ]
    Pfami PF00211. Guanylate_cyc. 2 hits.
    [Graphical view ]
    SMARTi SM00044. CYCc. 2 hits.
    [Graphical view ]
    SUPFAMi SSF55073. SSF55073. 2 hits.
    PROSITEi PS00452. GUANYLATE_CYCLASE_1. 2 hits.
    PS50125. GUANYLATE_CYCLASE_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiB8JK56_MOUSE
    AccessioniPrimary (citable) accession number: B8JK56
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3