Adenylate cyclase type 3 - Mus musculus (Mouse)

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B8JK56 (B8JK56_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 41. History...

Clusters with 100%, 90%, 50% identity |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info Customize order

Names and origin

Protein names

Submitted name:
Adenylate cyclase type 3 Ensembl ENSMUSP00000115644 Ensembl ENSMUSP00000122073

Gene names

Name:

Adcy3 Ensembl ENSMUSP00000115644 Ensembl ENSMUSP00000122073 MGI 99675

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000122073

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	1144 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities	Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. RuleBase RU000405
Caution	The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000115644 Ensembl ENSMUSP00000122073

Ontologies

Keywords
Ligand	Nucleotide-binding SAAS SAAS018297
Molecular function	Lyase SAAS SAAS018297 RuleBase RU000405
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	activation of adenylate cyclase activity Traceable author statement PubMed 7766992. Source: MGI intracellular signal transduction Inferred from electronic annotation. Source: InterPro
Cellular_component	cilium Inferred from direct assay PubMed 22179047. Source: MGI plasma membrane Traceable author statement PubMed 7766992. Source: MGI
Molecular_function	adenylate cyclase activity Traceable author statement PubMed 7766992. Source: MGI nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

Sequence

Length

Mass (Da)

Tools

B8JK56 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 989F69F858CEC87C
Show »

FASTA

1,144

128,998

        10         20         30         40         50         60 
MPRNQGFSDP EYSAEYSAEY SVSLPSDPDR GVGRTHEISV RNSGSCLCLP RFMRLTFVPE 

        70         80         90        100        110        120 
SLENLYQTYF KRQRHETLLV LVVFAALFDC YVVVMCAVVF SSDKLAPLMV AGFGLVLDII 

       130        140        150        160        170        180 
LFVLCKKGLL PDRVSRKVVP YLLWLLISAQ IFSYLGLNFS RAHAASDTVG WQAFFVFSFF 

       190        200        210        220        230        240 
ITLPLSLSPI VIISVVSCVV HTLVLGVTVA QQQQDELEGM QLLREILANV FLYLCAIIVG 

       250        260        270        280        290        300 
IMSYYMADRK HRKAFLEARQ SLEVKMNLEE QSQQQENLML SILPKHVADE MLKDMKKDES 

       310        320        330        340        350        360 
QKDQQQFNTM YMYRHENVSI LFADIVGFTQ LSSACSAQEL VKLLNELFAR FDKLAAKYHQ 

       370        380        390        400        410        420 
LRIKILGDCY YCICGLPDYR EDHAVCSILM GLAMVEAISY VREKTKTGVD MRVGVHTGTV 

       430        440        450        460        470        480 
LGGVLGQKRW QYDVWSTDVT VANKMEAGGI PGRVHISQST MDCLKGEFDV EPGDGGSRCD 

       490        500        510        520        530        540 
YLDEKGIETY LIIASKPEVK KTAQNGLNGS AVPNGAPASS KPSSPALIET KEPNGSAHAS 

       550        560        570        580        590        600 
GSTSEEAEEQ EAQADNPSFP NPRRRLRLQD LADRVVDASE DEHELNQLLN EALLERESAQ 

       610        620        630        640        650        660 
VVKKRNTFLL TMRFMDPEME TRYSVEKEKQ SGAAFSCSCV VLFCTAMVEI LIDPWLMTNY 

       670        680        690        700        710        720 
VTFVVGEVLL LILTICSMAA IFPRSFPKKL VAFSSWIDRT RWARNTWAML AIFILVMANV 

       730        740        750        760        770        780 
VDMLSCLQYY MGPYNMTAGM ELDGGCMENP KYYNYVAVLS LIATIMLVQV SHMVKLTLML 

       790        800        810        820        830        840 
LVTGAVTALN LYAWCPVFDE YDHKRFQEKD SPMVALEKMQ VLATPGLNGT DRLPLVPSKY 

       850        860        870        880        890        900 
SMTVMMFVMM LSFYYFSRHV EKLARTLFLW KIEVHDQKER VYEMRRWNEA LVTNMLPEHV 

       910        920        930        940        950        960 
ARHFLGSKKR DEELYSQSYD EIGVMFASLP NFADFYTEES INNGGIECLR FLNEIISDFD 

       970        980        990       1000       1010       1020 
SLLDNPKFRV ITKIKTIGST YMAASGVTPD VNTNGFTSSS KEEKSDKERW QHLADLADFA 

      1030       1040       1050       1060       1070       1080 
LAMKDTLTNI NNQSFNNFML RIGMNKGGVL AGVIGARKPH YDIWGNTVNV ASRMESTGVM 

      1090       1100       1110       1120       1130       1140 
GNIQVVEETQ VILREYGFRF VRRGPIFVKG KGELLTFFLK GRDRPAAFPN GSSVTLPHQV 


VDNP

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000115644 Ensembl ENSMUSP00000122073.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000115644 Ensembl ENSMUSP00000122073.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT572999 Genomic DNA. No translation available.
IPI	IPI00928224.
RefSeq	NP_001153008.1. NM_001159536.1. NP_001153009.1. NM_001159537.1.
UniGene	Mm.489807.
3D structure databases
SMR	B8JK56. Positions 307-493, 912-1098.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000124505; ENSMUSP00000122073; ENSMUSG00000020654. ENSMUST00000152065; ENSMUSP00000115644; ENSMUSG00000020654.
GeneID	104111.
KEGG	mmu:104111.
UCSC	uc007mxk.2. mouse.
Organism-specific databases
CTD	109.
MGI	MGI:99675. Adcy3.
Phylogenomic databases
GeneTree	ENSGT00700000104101.
HOVERGEN	HBG050458.
KO	K08043.
OrthoDB	EOG47M1X3.
Family and domain databases
Gene3D	3.30.70.1230. 2 hits.
InterPro	IPR001054. A/G_cyclase. IPR018297. A/G_cyclase_CS. [Graphical view]
Pfam	PF00211. Guanylate_cyc. 2 hits. [Graphical view]
SMART	SM00044. CYCc. 2 hits. [Graphical view]
SUPFAM	SSF55073. A/G_cyclase. 2 hits.
PROSITE	PS00452. GUANYLATE_CYCLASE_1. 2 hits. PS50125. GUANYLATE_CYCLASE_2. 2 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ADCY3. mouse.
NextBio	356544.
SOURCE	Search...

Entry information

Entry name

B8JK56_MOUSE

Accession

Primary (citable) accession number: B8JK56

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Other

Entry information