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B8JJF3

- B8JJF3_MOUSE

UniProt

B8JJF3 - B8JJF3_MOUSE

Protein
Submitted name:

Myotubularin-related protein 2

Gene

Mtmr2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. phosphatidylinositol phosphate phosphatase activity Source: MGI
    2. protein homodimerization activity Source: MGI

    GO - Biological processi

    1. dendritic spine maintenance Source: Ensembl
    2. dephosphorylation Source: MGI
    3. inositol phosphate dephosphorylation Source: MGI
    4. myelin assembly Source: MGI
    5. negative regulation of excitatory postsynaptic membrane potential Source: Ensembl
    6. negative regulation of myelination Source: MGI
    7. negative regulation of receptor catabolic process Source: Ensembl
    8. negative regulation of receptor internalization Source: Ensembl
    9. neuron development Source: MGI
    10. phosphatidylinositol dephosphorylation Source: MGI
    11. phosphatidylinositol metabolic process Source: MGI
    12. positive regulation of early endosome to late endosome transport Source: Ensembl
    13. protein tetramerization Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Myotubularin-related protein 2Imported
    Gene namesi
    Name:Mtmr2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 9

    Organism-specific databases

    MGIiMGI:1924366. Mtmr2.

    Subcellular locationi

    GO - Cellular componenti

    1. axon Source: Ensembl
    2. cytoplasm Source: MGI
    3. cytosol Source: Ensembl
    4. dendritic spine Source: Ensembl
    5. neuronal postsynaptic density Source: Ensembl
    6. nucleus Source: Ensembl
    7. synaptic membrane Source: Ensembl
    8. synaptic vesicle Source: Ensembl
    9. vacuolar membrane Source: MGI

    Structurei

    3D structure databases

    ProteinModelPortaliB8JJF3.
    SMRiB8JJF3. Positions 1-105.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00670000097670.
    HOGENOMiHOG000200754.
    HOVERGENiHBG085155.

    Family and domain databases

    Gene3Di2.30.29.30. 1 hit.
    InterProiIPR004182. GRAM.
    IPR011993. PH_like_dom.
    [Graphical view]
    PfamiPF02893. GRAM. 1 hit.
    [Graphical view]
    SMARTiSM00568. GRAM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    B8JJF3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEEPALLPGE NIKDMAKDVT YICPFTGAVR GTLTVTSYRL YFKSMERDPP    50
    FVLDASLGVI SRVEKIGGAS SRGENSYGLE TVCKDIRNLR FAHKPEGRTR 100
    RSIFE 105
    Length:105
    Mass (Da):11,759
    Last modified:March 3, 2009 - v1
    Checksum:iFC518BD55740FF18
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei105 – 1051Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT010488 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000152532; ENSMUSP00000114509; ENSMUSG00000031918.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT010488 Genomic DNA. No translation available.

    3D structure databases

    ProteinModelPortali B8JJF3.
    SMRi B8JJF3. Positions 1-105.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000152532 ; ENSMUSP00000114509 ; ENSMUSG00000031918 .

    Organism-specific databases

    MGIi MGI:1924366. Mtmr2.

    Phylogenomic databases

    GeneTreei ENSGT00670000097670.
    HOGENOMi HOG000200754.
    HOVERGENi HBG085155.

    Miscellaneous databases

    NextBioi 35547836.
    SOURCEi Search...

    Family and domain databases

    Gene3Di 2.30.29.30. 1 hit.
    InterProi IPR004182. GRAM.
    IPR011993. PH_like_dom.
    [Graphical view ]
    Pfami PF02893. GRAM. 1 hit.
    [Graphical view ]
    SMARTi SM00568. GRAM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (JUN-2011) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiB8JJF3_MOUSE
    AccessioniPrimary (citable) accession number: B8JJF3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3