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B8JJF3

- B8JJF3_MOUSE

UniProt

B8JJF3 - B8JJF3_MOUSE

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Protein
Submitted name:

Myotubularin-related protein 2

Gene

Mtmr2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. phosphatidylinositol phosphate phosphatase activity Source: MGI
  2. protein homodimerization activity Source: MGI

GO - Biological processi

  1. dendritic spine maintenance Source: Ensembl
  2. dephosphorylation Source: MGI
  3. inositol phosphate dephosphorylation Source: MGI
  4. myelin assembly Source: MGI
  5. negative regulation of excitatory postsynaptic membrane potential Source: Ensembl
  6. negative regulation of myelination Source: MGI
  7. negative regulation of receptor catabolic process Source: Ensembl
  8. negative regulation of receptor internalization Source: Ensembl
  9. neuron development Source: MGI
  10. phosphatidylinositol dephosphorylation Source: MGI
  11. phosphatidylinositol metabolic process Source: MGI
  12. positive regulation of early endosome to late endosome transport Source: Ensembl
  13. protein tetramerization Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Myotubularin-related protein 2Imported
Gene namesi
Name:Mtmr2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:1924366. Mtmr2.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: Ensembl
  2. cytoplasm Source: MGI
  3. cytosol Source: Ensembl
  4. dendritic spine Source: Ensembl
  5. neuronal postsynaptic density Source: Ensembl
  6. nucleus Source: Ensembl
  7. synaptic membrane Source: Ensembl
  8. synaptic vesicle Source: Ensembl
  9. vacuolar membrane Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiB8JJF3. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliB8JJF3.
SMRiB8JJF3. Positions 1-105.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00760000118832.
HOGENOMiHOG000200754.
HOVERGENiHBG085155.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR004182. GRAM.
IPR011993. PH_like_dom.
[Graphical view]
PfamiPF02893. GRAM. 1 hit.
[Graphical view]
SMARTiSM00568. GRAM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

B8JJF3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEEPALLPGE NIKDMAKDVT YICPFTGAVR GTLTVTSYRL YFKSMERDPP
60 70 80 90 100
FVLDASLGVI SRVEKIGGAS SRGENSYGLE TVCKDIRNLR FAHKPEGRTR

RSIFE
Length:105
Mass (Da):11,759
Last modified:March 3, 2009 - v1
Checksum:iFC518BD55740FF18
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei105 – 1051Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT010488 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000152532; ENSMUSP00000114509; ENSMUSG00000031918.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT010488 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali B8JJF3.
SMRi B8JJF3. Positions 1-105.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000152532 ; ENSMUSP00000114509 ; ENSMUSG00000031918 .

Organism-specific databases

MGIi MGI:1924366. Mtmr2.

Phylogenomic databases

GeneTreei ENSGT00760000118832.
HOGENOMi HOG000200754.
HOVERGENi HBG085155.

Miscellaneous databases

NextBioi 35547836.
SOURCEi Search...

Gene expression databases

ExpressionAtlasi B8JJF3. baseline and differential.

Family and domain databases

Gene3Di 2.30.29.30. 1 hit.
InterProi IPR004182. GRAM.
IPR011993. PH_like_dom.
[Graphical view ]
Pfami PF02893. GRAM. 1 hit.
[Graphical view ]
SMARTi SM00568. GRAM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (JUN-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB8JJF3_MOUSE
AccessioniPrimary (citable) accession number: B8JJF3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3