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Protein
Submitted name:

Tyrosyl-DNA phosphodiesterase 1

Gene

Tdp1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-5693571. Nonhomologous End-Joining (NHEJ).

Names & Taxonomyi

Protein namesi
Submitted name:
Tyrosyl-DNA phosphodiesterase 1Imported
Submitted name:
Tyrosyl-DNA phosphodiesterase 1, isoform CRA_bImported
Gene namesi
Name:Tdp1Imported
ORF Names:mCG_14730Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1920036. Tdp1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000021177.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG2031. Eukaryota.
ENOG410XQPZ. LUCA.
GeneTreeiENSGT00390000002211.
HOGENOMiHOG000067775.
HOVERGENiHBG061242.
KOiK10862.
OMAiNEPRYTC.
OrthoDBiEOG091G0DQF.
TreeFamiTF105989.

Family and domain databases

Gene3Di3.30.870.20. 1 hit.
InterProiView protein in InterPro
IPR010347. Tdp1.
IPR027415. TDP_C.
PANTHERiPTHR12415. PTHR12415. 1 hit.
PfamiView protein in Pfam
PF06087. Tyr-DNA_phospho. 1 hit.

Sequencei

Sequence statusi: Complete.

B8JJC1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQESSYGKW TISSSDESED EKPKPDKPSA SSHPQAGQGV SKELIYTCSE
60 70 80 90 100
ARKVAHKRQI SPVKFNDADS VLPHKKQKSD SPEGLGWCLS SSDDDQQPDV
110 120 130 140 150
TQQEQPKRVL PQEKKHVSSP DVTTAQKVVD RSPPASLRPQ RADDEYETSG
160 170 180 190 200
EGQDIWDMLD KGNPFQFYLT RVSGIKAKYN SKALHIKDIL SPLFGTLVSS
210 220 230 240 250
AQFNYCFDVD WLIKQYPPEF RKNPILLVHG DKREAKADLH AQAKPYANIS
260 270 280 290 300
LCQAKLDIAF GTHHTKMMLL LYEEGLRVVI HTSNLIREDW HQKTQGIWLS
310 320 330 340 350
PLYPRIDQGS HTAGESSTRF KADLTSYLTA YNAPPLQEWI DIIQEHDLSE
360 370 380 390 400
TNVYLIGSTP GRFQGSHRDN WGHFRLRKLL QAHAPSTPKG ECWPIVGQFS
410 420 430 440 450
SIGSLGPDES KWLCSEFKDS LLALREEGRP PGKSAVPLHL IYPSVENVRT
460 470 480 490 500
SLEGYPAGGS LPYSIQTAEK QRWLHSYFHK WSAETSGRSN AMPHIKTYMR
510 520 530 540 550
PSPDFSKLAW FLVTSANLSK AAWGALEKNG TQLMIRSYEL GVLFLPSAFG
560 570 580 590 600
LDTFKVKQKF FSSSCEPTAS FPVPYDLPPE LYGSKDRPWI WNIPYVKAPD

THGNMWVPS
Length:609
Mass (Da):68,590
Last modified:March 3, 2009 - v1
Checksum:iE23C5D98DC3E1FC9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC160931 Genomic DNA. No translation available.
CT010436 Genomic DNA. No translation available.
CH466549 Genomic DNA. Translation: EDL18908.1.
RefSeqiNP_082630.2. NM_028354.4.
UniGeneiMm.312323.
Mm.487464.
Mm.488658.

Genome annotation databases

EnsembliENSMUST00000021594; ENSMUSP00000021594; ENSMUSG00000021177.
ENSMUST00000153627; ENSMUSP00000118656; ENSMUSG00000021177.
GeneIDi104884.
KEGGimmu:104884.
UCSCiuc007osg.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiB8JJC1_MOUSE
AccessioniPrimary (citable) accession number: B8JJC1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: August 30, 2017
This is version 64 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported