ID   B8JEG0_ANAD2            Unreviewed;       789 AA.
AC   B8JEG0;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 61.
DE   SubName: Full=DNA ligase D, 3'-phosphoesterase domain protein {ECO:0000313|EMBL:ACL64286.1};
GN   OrderedLocusNames=A2cp1_0935 {ECO:0000313|EMBL:ACL64286.1};
OS   Anaeromyxobacter dehalogenans (strain 2CP-1 / ATCC BAA-258).
OC   Bacteria; Myxococcota; Myxococcia; Myxococcales; Cystobacterineae;
OC   Anaeromyxobacteraceae; Anaeromyxobacter.
OX   NCBI_TaxID=455488 {ECO:0000313|EMBL:ACL64286.1, ECO:0000313|Proteomes:UP000007089};
RN   [1] {ECO:0000313|Proteomes:UP000007089}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-1 / ATCC BAA-258 {ECO:0000313|Proteomes:UP000007089};
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C.,
RA   Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G.,
RA   Beliaev A.S., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-1.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001359; ACL64286.1; -; Genomic_DNA.
DR   RefSeq; WP_012632290.1; NC_011891.1.
DR   AlphaFoldDB; B8JEG0; -.
DR   KEGG; acp:A2cp1_0935; -.
DR   HOGENOM; CLU_008325_0_2_7; -.
DR   Proteomes; UP000007089; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   CDD; cd07906; Adenylation_DNA_ligase_LigD_LigC; 1.
DR   Gene3D; 3.30.1490.70; -; 1.
DR   Gene3D; 3.30.470.30; DNA ligase/mRNA capping enzyme; 1.
DR   Gene3D; 3.90.920.10; DNA primase, PRIM domain; 1.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR014144; LigD_PE_domain.
DR   InterPro; IPR014145; LigD_pol_dom.
DR   NCBIfam; TIGR02777; LigD_PE_dom; 1.
DR   PANTHER; PTHR42705; BIFUNCTIONAL NON-HOMOLOGOUS END JOINING PROTEIN LIGD; 1.
DR   PANTHER; PTHR42705:SF2; MULTIFUNCTIONAL NON-HOMOLOGOUS END JOINING DNA REPAIR PROTEIN LIGD; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF13298; LigD_N; 1.
DR   Pfam; PF21686; LigD_Prim-Pol; 1.
DR   SUPFAM; SSF56091; DNA ligase/mRNA capping enzyme, catalytic domain; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ACL64286.1};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          40..145
FT                   /note="DNA ligase D 3'-phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF13298"
FT   DOMAIN          231..401
FT                   /note="ATP-dependent DNA ligase family profile"
FT                   /evidence="ECO:0000259|Pfam:PF01068"
FT   DOMAIN          451..704
FT                   /note="DNA ligase D polymerase"
FT                   /evidence="ECO:0000259|Pfam:PF21686"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          728..749
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   789 AA;  84500 MW;  E4E05BE9463E1611 CRC64;
     MPDRLERYRA MRDPGRTPEP FGGGAPGEDG SGSARAFVVQ KHAARRLHWD FRLELGGTLR
     SWAVPKGPSA DPSDRRMAIE VEDHPVEYAD FEGIIPAGNY GAGAVIVWDR GAWWPVGDPE
     DGLARGKLVF RLRGHKLRGE WTLVRTRAGD GGKRQWLLLK HRGDPFAGPG RPFPEASVLS
     GRTVEELAAG TSRAEAAARE AARLGAPARP LPRRGPAPMA PGARRAPFDR AGWLFEVAQG
     GQRVSARREG TGAVLRSPQG EDLGPRFPEV ALAVALLPGD PVLDGELVVL DDEGRASAEA
     LEARARTGAS AAAGAALQRP ATLFAFDLLA LGGRDLRALA LADRKRLLAE VAPAVGSVRF
     AGHVEREGKA LHREAADRGL PGVLARRAAA PYRSGRSADW VLVPAARSAA PRPPAPRPRG
     DAPAATGAVP VERTVNVVHP EKVWFPEDGI TKGELVAYHR AIAPFMLPYL ADRPLVLTRF
     PEGIHGRSFL QEDAPAWRPR WLRAATVHAG EGGRTLDHLL VDDADGLAWL VDQGAIPLDV
     LAGRAGALER PDWCVLELDA GDAPFAQGVR VARALHALCD AAGLPSHVKT TGERGLHVLV
     PLGGQLTHAQ ARTLAELLAR TVEAELPDLA TTARTAAARG GRVHVDALRN GHGTAIAAPY
     TVRPRPGAPV STPLRWSEVN ARLDPARFTV RTVPARVARL GRDPLGPVLT ERPDLLRALA
     RLRARPGAVG CGRPARSAPF VTRRTPGDAT RRRARRLVVP ARMWGQVAEP RPGGDFAAMC
     RPTRNRSRQ
//