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B8J605 (B8J605_ANAD2) Unreviewed, UniProtKB/TrEMBL

Last modified December 11, 2013. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Ontologies

Keywords
   Molecular functionIsomerase EMBL ACL66900.1
   Technical term3D-structure PDB 4IGJ PDB 4KAE PDB 4KDY
Complete proteome
Gene Ontology (GO)
   Biological_processaromatic amino acid family metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: InterPro

   Molecular_functionisomerase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region8 – 103Citrate binding PDB 4KAE
Region70 – 712Glutathione binding
Region106 – 1105Glutathione binding
Region110 – 1134Sulfate binding PDB 4IGJ

Sites

Binding site111Glutathione
Binding site121Sulfate PDB 4IGJ
Binding site161Glutathione
Binding site351Citrate
Binding site381Glutathione
Binding site391Citrate PDB 4KAE
Binding site421Glutathione
Binding site541Glutathione; via amide nitrogen and carbonyl oxygen
Binding site1391Glutathione
Binding site1741Sulfate PDB 4IGJ
Binding site1771Citrate PDB 4KAE
Binding site2191Citrate PDB 4KAE

Sequences

Sequence LengthMass (Da)Tools
B8J605 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: C7372DFECE10BD63

FASTA22024,997
        10         20         30         40         50         60 
MTLRLYSYWR SSSAWRVRLG LALKGLAYEY RAVDLLAQEQ FQAAHQARNP MSQVPVLEVE 

        70         80         90        100        110        120 
EDGRTHLLVQ SMAILEWLEE RHPEPALLPP DLWGRARVRA LAEHVNSGTQ PMQNALVLRM 

       130        140        150        160        170        180 
LREKVPGWDR EWARFFIARG LAALETAVRD GAGRFSHGDA PTLADCYLVP QLYNARRFGL 

       190        200        210        220 
DLEPYPTLRR VDEACAALAP FQAAHPDRQP DAPPPDRRTP 

« Hide

References

« Hide 'large scale' references
[1]"Complete sequence of Anaeromyxobacter dehalogenans 2CP-1."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Beliaev A.S., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 2CP-1 / ATCC BAA-258.
[2]"Crystal structure of Maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, target EFI-507175."
Kim J., Toro R., Bhosle R., Al Obaidi N.F., Morisco L.L., Wasserman S.R., Sojitra S., Washington E., Scott Glenn A., Chowdhury S., Evans B., Hammonds J., Hillerich B., Love J., Seidel R.D., Imker H.J., Armstrong R.N., Gerlt J.A., Almo S.C.
Submitted (DEC-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.48 ANGSTROMS) IN COMPLEX WITH SULFATE.
[3]"Crystal structure of Maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, TARGET EFI-507175, with bound dicarboxyethyl glutathione and citrate in the active site."
Kim J., Toro R., Bhosle R., Al Obaidi N.F., Morisco L.L., Wasserman S.R., Sojitra S., Washington E., Scott Glenn A., Chowdhury S., Evans B., Hammonds J., Hillerich B., Love J., Seidel R.D., Imker H.J., Stead M., Gerlt J.A., Almo S.C., Enzyme Function Initiative
Submitted (APR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) IN COMPLEX WITH CITRATE.
[4]"Crystal structure of maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, Target EFI-507175, with bound GSH in the active site."
Kim J., Toro R., Bhosle R., Al Obaidi N.F., Morisco L.L., Wasserman S.R., Sojitra S., Washington E., Scott Glenn A., Chowdhury S., Evans B., Hammonds J., Hillerich B., Love J., Seidel R.D., Imker H.J., Stead M., Gerlt J.A., Almo S.C., Enzyme Function Initiative
Submitted (APR-2013) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) IN COMPLEX WITH CITRATE AND GLUTATHIONE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001359 Genomic DNA. Translation: ACL66900.1.
RefSeqYP_002493966.1. NC_011891.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
4IGJX-ray1.48A/B1-220[»]
4KAEX-ray1.50A/B1-220[»]
4KDYX-ray1.50A/B1-220[»]
ProteinModelPortalB8J605.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING455488.A2cp1_3570.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACL66900; ACL66900; A2cp1_3570.
GeneID7299620.
KEGGacp:A2cp1_3570.
PATRIC20914115. VBIAnaDeh28364_3622.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0625.
HOGENOMHOG000125758.
KOK01801.
OMAKKRASVR.
OrthoDBEOG6WT8DX.
ProtClustDBCLSK946669.

Enzyme and pathway databases

BioCycADEH455488:GH35-3619-MONOMER.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR005955. Mal_ac_isom.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
TIGRFAMsTIGR01262. maiA. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8J605_ANAD2
AccessionPrimary (citable) accession number: B8J605
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 11, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)