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B8J1X3 (GLSA_DESDA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutaminase
EC=3.5.1.2
Gene names
Name:glsA
Ordered Locus Names:Ddes_0048
OrganismDesulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949) [Complete proteome] [HAMAP]
Taxonomic identifier525146 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio ›

Protein attributes

Sequence length310 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamine + H2O = L-glutamate + NH3. HAMAP-Rule MF_00313

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the glutaminase family.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamine metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutaminase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 310310Glutaminase HAMAP-Rule MF_00313
PRO_1000132905

Sites

Binding site661Substrate By similarity
Binding site1171Substrate By similarity
Binding site1611Substrate By similarity
Binding site1681Substrate By similarity
Binding site1921Substrate By similarity
Binding site2441Substrate By similarity
Binding site2621Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
B8J1X3 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 3CB83637248A4013

FASTA31032,783
        10         20         30         40         50         60 
MPAIEKIQSV VNSAYAQFSK ASGGANADYI PFLANIPSDL AAVAVVTAQG QVAAAGDAQY 

        70         80         90        100        110        120 
RFAIESISKV CTLALALEDF GPQAVQEKIG TSPTGLPFNS VMALELHGDK PLSPLVNAGA 

       130        140        150        160        170        180 
MASASLVKAG STEERWQRIL DMQRRLGSKE IAISDELNQS EQTTNFHNRG IAWLLYSAGY 

       190        200        210        220        230        240 
MYCDPMEACD VYTRQCSTLL NTVELATVGA TIAARGRNPV TGEQVLKPEH CPCIMAEMTM 

       250        260        270        280        290        300 
EGMYDSSGDW AYKVGLPGKS GVGGGILTIV PGIMAIAAFS PPLDSVGNSV RGQKMAAFVA 

       310 
NELGYNLYKA

« Hide

References

[1]"Complete sequence of Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Lu M., Kiss H., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L. expand/collapse author list , Kyrpides N., Ovchinnikova G., Hazen T.C.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 27774 / DSM 6949.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001358 Genomic DNA. Translation: ACL47968.1.
RefSeqYP_002478646.1. NC_011883.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING525146.Ddes_0048.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACL47968; ACL47968; Ddes_0048.
GeneID7283699.
KEGGdds:Ddes_0048.
PATRIC21733336. VBIDesDes50650_0057.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2066.
HOGENOMHOG000216890.
KOK01425.
ProtClustDBPRK12356.

Enzyme and pathway databases

BioCycDDES525146:GIWF-48-MONOMER.

Family and domain databases

Gene3D3.40.710.10. 1 hit.
HAMAPMF_00313. Glutaminase.
InterProIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERPTHR12544. PTHR12544. 1 hit.
PfamPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMSSF56601. PBP_transp_fold. 1 hit.
TIGRFAMsTIGR03814. Gln_ase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLSA_DESDA
AccessionPrimary (citable) accession number: B8J1X3
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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