Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutaminase

Gene

glsA

Organism
Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei66 – 661SubstrateUniRule annotation
Binding sitei117 – 1171SubstrateUniRule annotation
Binding sitei161 – 1611SubstrateUniRule annotation
Binding sitei168 – 1681SubstrateUniRule annotation
Binding sitei192 – 1921SubstrateUniRule annotation
Binding sitei244 – 2441SubstrateUniRule annotation
Binding sitei262 – 2621Substrate; via amide nitrogenUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciDDES525146:GIWF-48-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
GlutaminaseUniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsAUniRule annotation
Ordered Locus Names:Ddes_0048
OrganismiDesulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)
Taxonomic identifieri525146 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
ProteomesiUP000002598 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 310310GlutaminasePRO_1000132905Add
BLAST

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi525146.Ddes_0048.

Structurei

3D structure databases

ProteinModelPortaliB8J1X3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiEMTMEGM.
OrthoDBiEOG6N94BK.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.

Sequencei

Sequence statusi: Complete.

B8J1X3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPAIEKIQSV VNSAYAQFSK ASGGANADYI PFLANIPSDL AAVAVVTAQG
60 70 80 90 100
QVAAAGDAQY RFAIESISKV CTLALALEDF GPQAVQEKIG TSPTGLPFNS
110 120 130 140 150
VMALELHGDK PLSPLVNAGA MASASLVKAG STEERWQRIL DMQRRLGSKE
160 170 180 190 200
IAISDELNQS EQTTNFHNRG IAWLLYSAGY MYCDPMEACD VYTRQCSTLL
210 220 230 240 250
NTVELATVGA TIAARGRNPV TGEQVLKPEH CPCIMAEMTM EGMYDSSGDW
260 270 280 290 300
AYKVGLPGKS GVGGGILTIV PGIMAIAAFS PPLDSVGNSV RGQKMAAFVA
310
NELGYNLYKA
Length:310
Mass (Da):32,783
Last modified:March 3, 2009 - v1
Checksum:i3CB83637248A4013
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001358 Genomic DNA. Translation: ACL47968.1.
RefSeqiWP_012623700.1. NC_011883.1.
YP_002478646.1. NC_011883.1.

Genome annotation databases

EnsemblBacteriaiACL47968; ACL47968; Ddes_0048.
KEGGidds:Ddes_0048.
PATRICi21733336. VBIDesDes50650_0057.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001358 Genomic DNA. Translation: ACL47968.1.
RefSeqiWP_012623700.1. NC_011883.1.
YP_002478646.1. NC_011883.1.

3D structure databases

ProteinModelPortaliB8J1X3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi525146.Ddes_0048.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL47968; ACL47968; Ddes_0048.
KEGGidds:Ddes_0048.
PATRICi21733336. VBIDesDes50650_0057.

Phylogenomic databases

eggNOGiCOG2066.
HOGENOMiHOG000216890.
KOiK01425.
OMAiEMTMEGM.
OrthoDBiEOG6N94BK.

Enzyme and pathway databases

BioCyciDDES525146:GIWF-48-MONOMER.

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
HAMAPiMF_00313. Glutaminase.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR015868. Glutaminase.
[Graphical view]
PANTHERiPTHR12544. PTHR12544. 1 hit.
PfamiPF04960. Glutaminase. 1 hit.
[Graphical view]
SUPFAMiSSF56601. SSF56601. 1 hit.
TIGRFAMsiTIGR03814. Gln_ase. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Lu M., Kiss H., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L.
    , Kyrpides N., Ovchinnikova G., Hazen T.C.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27774 / DSM 6949.

Entry informationi

Entry nameiGLSA_DESDA
AccessioniPrimary (citable) accession number: B8J1X3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: May 27, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.