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Protein

Glutamate decarboxylase

Gene

Ddes_0045

Organism
Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciDDES525146:GIWF-45-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Ddes_0045Imported
OrganismiDesulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)Imported
Taxonomic identifieri525146 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
ProteomesiUP000002598: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi525146.Ddes_0045.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDESEHYM.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

B8J1X0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTAKNTLRNT VLDDTYAASD MANAMPRHEM PQQESRPRDV YQAIHDELML
60 70 80 90 100
DGNSRQNLAT FCQTWVDPEI NQIMAECVDK NMIDKDEYPQ TAETETRCVH
110 120 130 140 150
MLADLWHSPD PKGTLGCSTT GSSEAAMLGG LAMKRRWVNM RKAAGKPYDK
160 170 180 190 200
PNMVCGPVQV CWEKFARYWD VELREIPMEK DRLIMTAEEV IKRCDENTIG
210 220 230 240 250
VVPTLGVTFT GQYEPVEEVS KALDKLQKDK GWDIPIHVDG ASGGFLAPFI
260 270 280 290 300
EPDLLWDFRL PRVKSINSSG HKFGLAPLGV GWVVWREKSD LPEDLIFNVN
310 320 330 340 350
YLGGNMPTFA LNFSRPGGQI IAQYYNFLRL GREGYRRIHQ NCYDTARFLG
360 370 380 390 400
DEIAKLGPFE VLYNGRGGIP ALCWTFKANA KTSYSLYDLS DRLRSRGWQV
410 420 430 440 450
PAYSMPAHRE DLVVMRVLVR HGFSRDLGSL LVDDLKRAMA HFDAHPVSKP
460
LSETEAGSNS HAGRAAKK
Length:468
Mass (Da):52,796
Last modified:March 3, 2009 - v1
Checksum:i4E505D0BF8A593B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001358 Genomic DNA. Translation: ACL47965.1.
RefSeqiYP_002478643.1. NC_011883.1.

Genome annotation databases

EnsemblBacteriaiACL47965; ACL47965; Ddes_0045.
GeneIDi7283696.
KEGGidds:Ddes_0045.
PATRICi21733330. VBIDesDes50650_0054.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001358 Genomic DNA. Translation: ACL47965.1.
RefSeqiYP_002478643.1. NC_011883.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi525146.Ddes_0045.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL47965; ACL47965; Ddes_0045.
GeneIDi7283696.
KEGGidds:Ddes_0045.
PATRICi21733330. VBIDesDes50650_0054.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiDESEHYM.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciDDES525146:GIWF-45-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Lu M., Kiss H., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L.
    , Kyrpides N., Ovchinnikova G., Hazen T.C.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27774 / DSM 6949Imported.

Entry informationi

Entry nameiB8J1X0_DESDA
AccessioniPrimary (citable) accession number: B8J1X0
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: February 4, 2015
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.