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Protein

Glutamate decarboxylase

Gene

Ddes_0045

Organism
Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDecarboxylaseUniRule annotation, Lyase
LigandPyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciDDES525146:G1GUN-47-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:Ddes_0045Imported
OrganismiDesulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)Imported
Taxonomic identifieri525146 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
Proteomesi
  • UP000002598 Componenti: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei272N6-(pyridoxal phosphate)lysineUniRule annotation1

Interactioni

Protein-protein interaction databases

STRINGi525146.Ddes_0045

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CVK Bacteria
COG0076 LUCA
HOGENOMiHOG000070228
KOiK01580
OMAiRPNLVMG
OrthoDBiPOG091H06F5

Family and domain databases

Gene3Di3.40.640.10, 1 hit
InterProiView protein in InterPro
IPR010107 Glutamate_decarboxylase
IPR002129 PyrdxlP-dep_de-COase
IPR015424 PyrdxlP-dep_Trfase
IPR015421 PyrdxlP-dep_Trfase_major
PANTHERiPTHR43321 PTHR43321, 1 hit
PfamiView protein in Pfam
PF00282 Pyridoxal_deC, 1 hit
SUPFAMiSSF53383 SSF53383, 1 hit
TIGRFAMsiTIGR01788 Glu-decarb-GAD, 1 hit

Sequencei

Sequence statusi: Complete.

B8J1X0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTAKNTLRNT VLDDTYAASD MANAMPRHEM PQQESRPRDV YQAIHDELML
60 70 80 90 100
DGNSRQNLAT FCQTWVDPEI NQIMAECVDK NMIDKDEYPQ TAETETRCVH
110 120 130 140 150
MLADLWHSPD PKGTLGCSTT GSSEAAMLGG LAMKRRWVNM RKAAGKPYDK
160 170 180 190 200
PNMVCGPVQV CWEKFARYWD VELREIPMEK DRLIMTAEEV IKRCDENTIG
210 220 230 240 250
VVPTLGVTFT GQYEPVEEVS KALDKLQKDK GWDIPIHVDG ASGGFLAPFI
260 270 280 290 300
EPDLLWDFRL PRVKSINSSG HKFGLAPLGV GWVVWREKSD LPEDLIFNVN
310 320 330 340 350
YLGGNMPTFA LNFSRPGGQI IAQYYNFLRL GREGYRRIHQ NCYDTARFLG
360 370 380 390 400
DEIAKLGPFE VLYNGRGGIP ALCWTFKANA KTSYSLYDLS DRLRSRGWQV
410 420 430 440 450
PAYSMPAHRE DLVVMRVLVR HGFSRDLGSL LVDDLKRAMA HFDAHPVSKP
460
LSETEAGSNS HAGRAAKK
Length:468
Mass (Da):52,796
Last modified:March 3, 2009 - v1
Checksum:i4E505D0BF8A593B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001358 Genomic DNA Translation: ACL47965.1
RefSeqiWP_012623697.1, NC_011883.1

Genome annotation databases

EnsemblBacteriaiACL47965; ACL47965; Ddes_0045
KEGGidds:Ddes_0045

Similar proteinsi

Entry informationi

Entry nameiB8J1X0_DESDA
AccessioniPrimary (citable) accession number: B8J1X0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 25, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health