B8J162 (TRPF_DESDA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase
Short name=PRAI
EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	Ddes_1589

Organism

Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949) [Complete proteome] [HAMAP]

Taxonomic identifier

525146 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Deltaproteobacteria › Desulfovibrionales › Desulfovibrionaceae › Desulfovibrio › Desulfovibrio desulfuricans › Desulfovibrio desulfuricans subsp. desulfuricans

Protein attributes

Sequence length	211 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP-Rule MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP-Rule MF_00135
Sequence similarities	Belongs to the TrpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 211	211	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP-Rule MF_00135		PRO_1000197101

Sequences

	Sequence		Length	Mass (Da)
	B8J162 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: E44395C7F29B6810	FASTA	211	22,447
	10 20 30 40 50 60 MLIKVCGLTR QADVDLAASF GASMCGFIFH PVSPRCVSPV QAASLESGSM LRVGVFVEQD 70 80 90 100 110 120 AEEICRIMAE ARLDMAQLHG RQDAACARAV GAQRVIRVIW PARYCHRALL YNELQNHADA 130 140 150 160 170 180 CACYLLDAGL AGGGSGVRLD WEDLNHLPSP RPWLLAGGLS AENVGLALSR CSPDGVDFNS 190 200 210 GVEDAPGQKN AQKLAAALAV AAKQKGNRYL S

References

[1]

"Complete sequence of Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Lu M., Kiss H., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L. , Kyrpides N., Ovchinnikova G., Hazen T.C. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 27774 / DSM 6949.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001358 Genomic DNA. Translation: ACL49489.1.
RefSeq	YP_002480167.1. NC_011883.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	525146.Ddes_1589.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACL49489; ACL49489; Ddes_1589.
GeneID	7285287.
KEGG	dds:Ddes_1589.
PATRIC	21736986. VBIDesDes50650_1841.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0135.
HOGENOM	HOG000161598.
KO	K01817.
ProtClustDB	CLSK704643.
Enzyme and pathway databases
BioCyc	DDES525146:GIWF-1636-MONOMER.
UniPathway	UPA00035; UER00042.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00135. PRAI.
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

TRPF_DESDA

Accession

Primary (citable) accession number: B8J162

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program