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B8J008

- MUTS_DESDA

UniProt

B8J008 - MUTS_DESDA

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Protein

DNA mismatch repair protein MutS

Gene

mutS

Organism
Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi646 – 6538ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. damaged DNA binding Source: UniProtKB-HAMAP
  3. mismatched DNA binding Source: InterPro

GO - Biological processi

  1. mismatch repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA repair

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciDDES525146:GIWF-1212-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
DNA mismatch repair protein MutSUniRule annotation
Gene namesi
Name:mutSUniRule annotation
Ordered Locus Names:Ddes_1181
OrganismiDesulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)
Taxonomic identifieri525146 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
ProteomesiUP000002598: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 927927DNA mismatch repair protein MutSPRO_1000118680Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi525146.Ddes_1181.

Family & Domainsi

Sequence similaritiesi

Belongs to the DNA mismatch repair MutS family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0249.
HOGENOMiHOG000221407.
KOiK03555.
OrthoDBiEOG6Q5NPV.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00096. MutS.
InterProiIPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view]
SMARTiSM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view]
SUPFAMiSSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsiTIGR01070. mutS1. 1 hit.
PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8J008-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSEPTFKMTP MFEHYMSIKA DYPDALLFYR MGDFYELFFD DAELAARELQ
60 70 80 90 100
ITLTSRSRDP NNPIPMCGVP WHAVDTYVAQ LVDKGYHIAI CDQVEDPKTS
110 120 130 140 150
KGLVKRAVTS VKTPGTVLDD ANLSTKSHNY LGALCPGSDA EKGGFAWLDV
160 170 180 190 200
STGQWSGVDF RRQTELWQWV LKMAPRELLV PEGFQPPART LLEGIRLVRL
210 220 230 240 250
PLSRFDLKRS TERVLAAQGV REAAALGLEG REEIMRACGA LLAYLAQTQM
260 270 280 290 300
RSPEHLQPFL RLDLSRRLII DEVTERNLEI FTRLNGRKGK GTLRHVLDET
310 320 330 340 350
MTPMGGRLLE DMLRHPWREI SPIVRIQDAV EWFYVDDGRR TALREALNGV
360 370 380 390 400
YDMERLSTRI SLNQGSPRDF IALRNSLAAL PQVFTALIEP TTSLLLRPDQ
410 420 430 440 450
EKDASENTSQ ENGLTQPRAL TELLKTWDAM EDCAQLLQSA LVDNPPPVIT
460 470 480 490 500
DGGLFKSGYN AELDRLLDLA EHGEQKLQAM LAEEQSTTGI AKLKLGYNRV
510 520 530 540 550
FGYYFEVSRA AHSGTVPYHF IRRQSLANAE RFTTEALKNL EEELLSASDK
560 570 580 590 600
RKALEYTLFQ DLRQHMADQR ERIAHMAQLI AHLDYWQSLA QVGRLNNWCR
610 620 630 640 650
PGLETDGNLT IREGRHPVVE AMIGRANFVP NDFRLDEKRR LCLLTGPNMA
660 670 680 690 700
GKSTVLRQVA IICLLAQMGS MVPATSARLG LVDRLFSRVG ASDNLAQGQS
710 720 730 740 750
TFMVEMMETA RILRQATKRS LIILDEIGRG TSTYDGVALA WAMVEDLSRR
760 770 780 790 800
AQGELRTLFA THYHELTALE GRVDGVFTMN IAISEYSGDI LFLHKLVPGP
810 820 830 840 850
ADRSYGVEVA RLAGVPGPVV QRARAILANL ERGRDVARKA VVSAVCLPGI
860 870 880 890 900
DLPETGPEED MPVLQAAPPR SEHPVIELLR QIEPEELSPL DALKTLMEWK
910 920
KLWSAQPGSA EQGESPDKHD EGKNSRG
Length:927
Mass (Da):103,825
Last modified:March 3, 2009 - v1
Checksum:iC5B9B38A6612CD86
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001358 Genomic DNA. Translation: ACL49085.1.
RefSeqiYP_002479763.1. NC_011883.1.

Genome annotation databases

EnsemblBacteriaiACL49085; ACL49085; Ddes_1181.
GeneIDi7284863.
KEGGidds:Ddes_1181.
PATRICi21736046. VBIDesDes50650_1384.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001358 Genomic DNA. Translation: ACL49085.1 .
RefSeqi YP_002479763.1. NC_011883.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 525146.Ddes_1181.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL49085 ; ACL49085 ; Ddes_1181 .
GeneIDi 7284863.
KEGGi dds:Ddes_1181.
PATRICi 21736046. VBIDesDes50650_1384.

Phylogenomic databases

eggNOGi COG0249.
HOGENOMi HOG000221407.
KOi K03555.
OrthoDBi EOG6Q5NPV.

Enzyme and pathway databases

BioCyci DDES525146:GIWF-1212-MONOMER.

Family and domain databases

Gene3Di 3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPi MF_00096. MutS.
InterProi IPR005748. DNA_mismatch_repair_MutS-1.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR000432. DNA_mismatch_repair_MutS_C.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PF00488. MutS_V. 1 hit.
[Graphical view ]
SMARTi SM00534. MUTSac. 1 hit.
SM00533. MUTSd. 1 hit.
[Graphical view ]
SUPFAMi SSF48334. SSF48334. 1 hit.
SSF52540. SSF52540. 1 hit.
SSF53150. SSF53150. 1 hit.
SSF55271. SSF55271. 1 hit.
TIGRFAMsi TIGR01070. mutS1. 1 hit.
PROSITEi PS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Lu M., Kiss H., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L.
    , Kyrpides N., Ovchinnikova G., Hazen T.C.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 27774 / DSM 6949.

Entry informationi

Entry nameiMUTS_DESDA
AccessioniPrimary (citable) accession number: B8J008
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3