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B8J008

- MUTS_DESDA

UniProt

B8J008 - MUTS_DESDA

Protein

DNA mismatch repair protein MutS

Gene

mutS

Organism
Desulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    • Comment

    Functioni

    This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi646 – 6538ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. damaged DNA binding Source: UniProtKB-HAMAP
    3. mismatched DNA binding Source: InterPro

    GO - Biological processi

    1. mismatch repair Source: UniProtKB-HAMAP

    Keywords - Biological processi

    DNA damage, DNA repair

    Keywords - Ligandi

    ATP-binding, DNA-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciDDES525146:GIWF-1212-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    DNA mismatch repair protein MutSUniRule annotation
    Gene namesi
    Name:mutSUniRule annotation
    Ordered Locus Names:Ddes_1181
    OrganismiDesulfovibrio desulfuricans (strain ATCC 27774 / DSM 6949)
    Taxonomic identifieri525146 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaDeltaproteobacteriaDesulfovibrionalesDesulfovibrionaceaeDesulfovibrio
    ProteomesiUP000002598: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 927927DNA mismatch repair protein MutSPRO_1000118680Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi525146.Ddes_1181.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the DNA mismatch repair MutS family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0249.
    HOGENOMiHOG000221407.
    KOiK03555.
    OrthoDBiEOG6Q5NPV.

    Family and domain databases

    Gene3Di3.30.420.110. 1 hit.
    3.40.1170.10. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPiMF_00096. MutS.
    InterProiIPR005748. DNA_mismatch_repair_MutS-1.
    IPR007695. DNA_mismatch_repair_MutS-lik_N.
    IPR000432. DNA_mismatch_repair_MutS_C.
    IPR007861. DNA_mismatch_repair_MutS_clamp.
    IPR007696. DNA_mismatch_repair_MutS_core.
    IPR016151. DNA_mismatch_repair_MutS_N.
    IPR007860. DNA_mmatch_repair_MutS_con_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PfamiPF01624. MutS_I. 1 hit.
    PF05188. MutS_II. 1 hit.
    PF05192. MutS_III. 1 hit.
    PF05190. MutS_IV. 1 hit.
    PF00488. MutS_V. 1 hit.
    [Graphical view]
    SMARTiSM00534. MUTSac. 1 hit.
    SM00533. MUTSd. 1 hit.
    [Graphical view]
    SUPFAMiSSF48334. SSF48334. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF53150. SSF53150. 1 hit.
    SSF55271. SSF55271. 1 hit.
    TIGRFAMsiTIGR01070. mutS1. 1 hit.
    PROSITEiPS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8J008-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSEPTFKMTP MFEHYMSIKA DYPDALLFYR MGDFYELFFD DAELAARELQ    50
    ITLTSRSRDP NNPIPMCGVP WHAVDTYVAQ LVDKGYHIAI CDQVEDPKTS 100
    KGLVKRAVTS VKTPGTVLDD ANLSTKSHNY LGALCPGSDA EKGGFAWLDV 150
    STGQWSGVDF RRQTELWQWV LKMAPRELLV PEGFQPPART LLEGIRLVRL 200
    PLSRFDLKRS TERVLAAQGV REAAALGLEG REEIMRACGA LLAYLAQTQM 250
    RSPEHLQPFL RLDLSRRLII DEVTERNLEI FTRLNGRKGK GTLRHVLDET 300
    MTPMGGRLLE DMLRHPWREI SPIVRIQDAV EWFYVDDGRR TALREALNGV 350
    YDMERLSTRI SLNQGSPRDF IALRNSLAAL PQVFTALIEP TTSLLLRPDQ 400
    EKDASENTSQ ENGLTQPRAL TELLKTWDAM EDCAQLLQSA LVDNPPPVIT 450
    DGGLFKSGYN AELDRLLDLA EHGEQKLQAM LAEEQSTTGI AKLKLGYNRV 500
    FGYYFEVSRA AHSGTVPYHF IRRQSLANAE RFTTEALKNL EEELLSASDK 550
    RKALEYTLFQ DLRQHMADQR ERIAHMAQLI AHLDYWQSLA QVGRLNNWCR 600
    PGLETDGNLT IREGRHPVVE AMIGRANFVP NDFRLDEKRR LCLLTGPNMA 650
    GKSTVLRQVA IICLLAQMGS MVPATSARLG LVDRLFSRVG ASDNLAQGQS 700
    TFMVEMMETA RILRQATKRS LIILDEIGRG TSTYDGVALA WAMVEDLSRR 750
    AQGELRTLFA THYHELTALE GRVDGVFTMN IAISEYSGDI LFLHKLVPGP 800
    ADRSYGVEVA RLAGVPGPVV QRARAILANL ERGRDVARKA VVSAVCLPGI 850
    DLPETGPEED MPVLQAAPPR SEHPVIELLR QIEPEELSPL DALKTLMEWK 900
    KLWSAQPGSA EQGESPDKHD EGKNSRG 927
    Length:927
    Mass (Da):103,825
    Last modified:March 3, 2009 - v1
    Checksum:iC5B9B38A6612CD86
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001358 Genomic DNA. Translation: ACL49085.1.
    RefSeqiWP_012624810.1. NC_011883.1.
    YP_002479763.1. NC_011883.1.

    Genome annotation databases

    EnsemblBacteriaiACL49085; ACL49085; Ddes_1181.
    GeneIDi7284863.
    KEGGidds:Ddes_1181.
    PATRICi21736046. VBIDesDes50650_1384.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001358 Genomic DNA. Translation: ACL49085.1 .
    RefSeqi WP_012624810.1. NC_011883.1.
    YP_002479763.1. NC_011883.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 525146.Ddes_1181.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACL49085 ; ACL49085 ; Ddes_1181 .
    GeneIDi 7284863.
    KEGGi dds:Ddes_1181.
    PATRICi 21736046. VBIDesDes50650_1384.

    Phylogenomic databases

    eggNOGi COG0249.
    HOGENOMi HOG000221407.
    KOi K03555.
    OrthoDBi EOG6Q5NPV.

    Enzyme and pathway databases

    BioCyci DDES525146:GIWF-1212-MONOMER.

    Family and domain databases

    Gene3Di 3.30.420.110. 1 hit.
    3.40.1170.10. 1 hit.
    3.40.50.300. 1 hit.
    HAMAPi MF_00096. MutS.
    InterProi IPR005748. DNA_mismatch_repair_MutS-1.
    IPR007695. DNA_mismatch_repair_MutS-lik_N.
    IPR000432. DNA_mismatch_repair_MutS_C.
    IPR007861. DNA_mismatch_repair_MutS_clamp.
    IPR007696. DNA_mismatch_repair_MutS_core.
    IPR016151. DNA_mismatch_repair_MutS_N.
    IPR007860. DNA_mmatch_repair_MutS_con_dom.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    Pfami PF01624. MutS_I. 1 hit.
    PF05188. MutS_II. 1 hit.
    PF05192. MutS_III. 1 hit.
    PF05190. MutS_IV. 1 hit.
    PF00488. MutS_V. 1 hit.
    [Graphical view ]
    SMARTi SM00534. MUTSac. 1 hit.
    SM00533. MUTSd. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48334. SSF48334. 1 hit.
    SSF52540. SSF52540. 1 hit.
    SSF53150. SSF53150. 1 hit.
    SSF55271. SSF55271. 1 hit.
    TIGRFAMsi TIGR01070. mutS1. 1 hit.
    PROSITEi PS00486. DNA_MISMATCH_REPAIR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Lu M., Kiss H., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L.
      , Kyrpides N., Ovchinnikova G., Hazen T.C.
      Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 27774 / DSM 6949.

    Entry informationi

    Entry nameiMUTS_DESDA
    AccessioniPrimary (citable) accession number: B8J008
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3