B8IXK8 (B8IXK8_METNO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Inositol 2-dehydrogenase HAMAP MF_01671
EC=1.1.1.18 HAMAP MF_01671

Alternative name(s):
Myo-inositol 2-dehydrogenase HAMAP MF_01671

Gene names

Name:	iolG HAMAP MF_01671
Ordered Locus Names:	Mnod_7807

Encoded on

Plasmid pMNOD02 EMBL ACL62840.1

Organism

Methylobacterium nodulans (strain ORS2060 / LMG 21967) [Complete proteome] [HAMAP]

Taxonomic identifier

460265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose) By similarity. HAMAP MF_01671
Catalytic activity	Myo-inositol + NAD+ = 2,4,6/3,5-pentahydroxycyclohexanone + NADH. HAMAP MF_01671 SAAS SAAS000683
Subunit structure	Homotetramer By similarity. SAAS SAAS000683 HAMAP MF_01671
Sequence similarities	Belongs to the gfo/idh/mocA family. HAMAP MF_01671

Ontologies

Keywords
Ligand	NAD SAAS SAAS000683 HAMAP MF_01671
Molecular function	Oxidoreductase SAAS SAAS000683 HAMAP MF_01671 EMBL ACL62840.1
Technical term	Complete proteome Plasmid EMBL ACL62840.1
Gene Ontology (GO)
Biological process	inositol catabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	inositol 2-dehydrogenase activity Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8IXK8 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 7E5A482A0E917B09	FASTA	336	36,444
	10 20 30 40 50 60 MTVRVGIIGT GAIGREHARR IEQVLSGGKV VALSDVNATS AEAVRAEIAR DARLFETGEA 70 80 90 100 110 120 LIASPDVDAV LVTSWGATHE QYVLAAIAAG KPCFCEKPLA TTAEGARRIV DAEVAHGKRL 130 140 150 160 170 180 VQVGFMRRYD AGYIALKQAV KSHTGAPILV HAAHRNPAVP EQYVTPMAIH DTLIHEIDVL 190 200 210 220 230 240 RWLLDDDYVS ARVLFPRKAA RSHAKLRDPQ VVVLETKKGV LIDVEIFVNC HYGYDIQCEV 250 260 270 280 290 300 VGEDGIARLP EPMAVEMRLD AKRQNAILTD WKDRFIASYD VELQDFLKAA AAGTASGPTS 310 320 330 WDGYVAAITS DACVEAQERA GEAVAITLPA RPSLYN

References

[1]

"Complete sequence of plasmid 2 of Methylobacterium nodulans ORS 2060." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ORS2060 / LMG 21967.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001351 Genomic DNA. Translation: ACL62840.1.
RefSeq	YP_002490007.1. NC_011887.1.
3D structure databases
ProteinModelPortal	B8IXK8.
ModBase	Search...
Protein-protein interaction databases
STRING	B8IXK8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7295757.
GenomeReviews	Gene locus Mnod_7807 in contig CP001351_GR.
KEGG	mno:Mnod_7807.
PATRIC	22540552. VBIMetNod76414_0034.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG612336.
OMA	YDVELQD.
ProtClustDB	CLSK800746.
Family and domain databases
HAMAP	MF_01671. IolG. [Tree]
InterPro	IPR023794. MI/DCI_dehydrogenase. IPR016040. NAD(P)-bd_dom. IPR000683. Oxidoreductase_N. IPR004104. OxRdtase_C. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00010.
PANTHER	PTHR22604:SF7. PTHR22604:SF7. 1 hit.
Pfam	PF01408. GFO_IDH_MocA. 1 hit. PF02894. GFO_IDH_MocA_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8IXK8_METNO

Accession

Primary (citable) accession number: B8IXK8

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)