B8IVT4 (B8IVT4_METNO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Betaine aldehyde dehydrogenase EMBL ACL62524.1

Gene names

Ordered Locus Names:

Mnod_8400

Encoded on

Plasmid pMNOD01 EMBL ACL62524.1

Organism

Methylobacterium nodulans (strain ORS2060 / LMG 21967) [Complete proteome] [HAMAP]

Taxonomic identifier

460265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	489 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Betaine aldehyde + NAD+ + H2O = betaine + NADH. SAAS SAAS011264
Pathway	Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1. SAAS SAAS011264
Sequence similarities	Belongs to the aldehyde dehydrogenase family. RuleBase RU003345

Ontologies

Keywords
Ligand	NAD SAAS SAAS011264
Molecular function	Oxidoreductase RuleBase RU003344 SAAS SAAS011264
Technical term	Complete proteome Plasmid EMBL ACL62524.1
Gene Ontology (GO)
Biological process	betaine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	betaine-aldehyde dehydrogenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8IVT4 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 514265FA08A4A389	FASTA	489	51,992
	10 20 30 40 50 60 MLLTDIQRPF IGGRLAEEAG RCTFRSVNPA TGEILAEVEH ATREDLEAAV AAAARGQAVW 70 80 90 100 110 120 AATPARERGR VLMRAVALLR ARNDELARLE SLDTGKPIAE TRVVDVATGA DVLEYYAGLA 130 140 150 160 170 180 AAIEGRQIPL RETSFVYTRR EPLGIVAGIG AWNYPIQIAL WKSAPALAAG NAMIFKPSEV 190 200 210 220 230 240 TPLTAFALAG IYAEAGLPDG VFSVLPGLGG EIGAWLTEHP AIAKVSFTGG TLTGAKVMAG 250 260 270 280 290 300 AARSTLKEVT MELGGKSPLI VLDDADLDRA ADIAVAANFF SSGQICTNGT RVFVPAPLKA 310 320 330 340 350 360 AFEARVLKRV ARIRIGDPLD EATNFGPLAS HAHRDKVLAF IRSGVEQGAR LLIGGHALEG 370 380 390 400 410 420 RFAAGAYVAP TVFTDCRDDM EIVREEIFGP VMSLLPYESE AEALARANAT LYGLAAGVVT 430 440 450 460 470 480 RDLARAHRIT HGLQAGICWI NTWGESPPEM PVGGTKQSGI GRENGIETLE RYTRTKSIQV ELSDFAPLF

References

[1]

"Complete sequence of plasmid 1 of Methylobacterium nodulans ORS 2060." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ORS2060 / LMG 21967.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001350 Genomic DNA. Translation: ACL62524.1.
RefSeq	YP_002495016.1. NC_011892.1.
3D structure databases
ProteinModelPortal	B8IVT4.
ModBase	Search...
Protein-protein interaction databases
STRING	B8IVT4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7300665.
GenomeReviews	Gene locus Mnod_8400 in contig CP001350_GR.
KEGG	mno:Mnod_8400.
PATRIC	22541570. VBIMetNod76414_0541.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG752218.
OMA	RAHRITH.
ProtClustDB	PRK13252.
Family and domain databases
InterPro	IPR016161. Ald_DH/histidinol_DH. IPR016163. Ald_DH_C. IPR016160. Ald_DH_CS. IPR016162. Ald_DH_N. IPR015590. Aldehyde_DH_dom. IPR011264. Betaine_Ald_DH. [Graphical view]
Gene3D	G3DSA:3.40.309.10. Aldehyde_dehydrogenase_C. 1 hit. G3DSA:3.40.605.10. Aldehyde_dehydrogenase_N. 1 hit.
KO	K00130.
Pfam	PF00171. Aldedh. 1 hit. [Graphical view]
SUPFAM	SSF53720. Aldehyde_DH/Histidinol_DH. 1 hit.
TIGRFAMs	TIGR01804. BADH. 1 hit.
PROSITE	PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit. PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8IVT4_METNO

Accession

Primary (citable) accession number: B8IVT4

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)