B8ILI8 (B8ILI8_METNO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut EMBL ACL60187.1
EC=3.6.1.23 EMBL ACL60187.1

Gene names

Ordered Locus Names:

Mnod_5342

Organism

Methylobacterium nodulans (strain ORS2060 / LMG 21967) [Complete proteome] [HAMAP]

Taxonomic identifier

460265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	161 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA By similarity. SAAS SAAS008181
Catalytic activity	dUTP + H2O = dUMP + diphosphate. SAAS SAAS008181
Cofactor	Magnesium By similarity. SAAS SAAS008181

Ontologies

Keywords
Biological process	Nucleotide metabolism SAAS SAAS008181
Ligand	Magnesium SAAS SAAS008181 Metal-binding SAAS SAAS008181
Molecular function	Hydrolase SAAS SAAS008181 EMBL ACL60187.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	dUTP metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	dUTP diphosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8ILI8 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: CDAB86DE5B36D4AD	FASTA	161	16,701
	10 20 30 40 50 60 MRADDLAVEV RILDPRLPGW GFPRWGSALA AGLDLHACLD APLALAPQAA PALVPAGFAV 70 80 90 100 110 120 AIRDPGWCAL VFPRSGLGHR EGLVLGNTVG VIDADYEGPL MLSVWNRNPP GSGSALTIAP 130 140 150 160 GERIAQLVFT RVTRPGLRVV ESFSGEAAVR GAGGFGSTGL R

References

[1]

"Complete sequence of chromosome of Methylobacterium nodulans ORS 2060." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ORS2060 / LMG 21967.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001349 Genomic DNA. Translation: ACL60187.1.
RefSeq	YP_002500490.1. NC_011894.1.
3D structure databases
ProteinModelPortal	B8ILI8.
ModBase	Search...
Protein-protein interaction databases
STRING	B8ILI8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7301931.
GenomeReviews	Gene locus Mnod_5342 in contig CP001349_GR.
KEGG	mno:Mnod_5342.
PATRIC	22552533. VBIMetNod76414_5960.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG436079.
OMA	LDLRACI.
ProtClustDB	CLSK2330713.
Family and domain databases
InterPro	IPR008180. dUTP_pyroPase. IPR008181. dUTP_pyroPase_sf. [Graphical view]
KO	K01520.
PANTHER	PTHR11241. PTHR11241. 1 hit.
Pfam	PF00692. dUTPase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00576. Dut. 1 hit.
ProtoNet	Search...

Entry information

Entry name

B8ILI8_METNO

Accession

Primary (citable) accession number: B8ILI8

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)