B8ILB4 (B8ILB4_METNO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Phosphorylase RuleBase RU000587
EC=2.4.1.1 RuleBase RU000587

Gene names

Ordered Locus Names:

Mnod_5267

Organism

Methylobacterium nodulans (strain ORS2060 / LMG 21967) [Complete proteome] [HAMAP]

Taxonomic identifier

460265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	839 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties By similarity. RuleBase RU000587
Catalytic activity	(1,4-alpha-D-glucosyl)(n) + phosphate = (1,4-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate. RuleBase RU000587
Cofactor	Pyridoxal phosphate By similarity. RuleBase RU000587
Sequence similarities	Belongs to the glycogen phosphorylase family. RuleBase RU004179

Ontologies

Keywords
Biological process	Carbohydrate metabolism RuleBase RU000587
Molecular function	Glycosyltransferase RuleBase RU000587 EMBL ACL60113.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphorylase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8ILB4 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 0C4AD48D3930D732	FASTA	839	92,473
	10 20 30 40 50 60 MLNEVLLAGD RRTDAAADEP RAGWRPPVPS LSPSADTVTL LHDAILRKLA YAIGKSPATA 70 80 90 100 110 120 RDRDWFAATA LALRDRVLDA CLSSAAPPVP QKRVYYLSLE FLIGRLLSDV MGNLGLAETA 130 140 150 160 170 180 RAALAQLGVD LDAVAGAEPD AALGNGGLGR LAACFMESMA SLAIPAYGYG IRYDHGLFRQ 190 200 210 220 230 240 VIEDGIQREV PETWLAEGNP WEFERPDSAC MVGFGGEVAM TVLADGAIRR VWRPAELVRA 250 260 270 280 290 300 VPFDTPVVGW GARHVNVLRL WQARALEPID LARFNAGDHV GAVAERSRVE AISRVLYPSD 310 320 330 340 350 360 GTPAGQELRL RQEFFFTSAS LQDLVRRHIA ERGDLRTLPD HAAIQLNDTH PAIAVPELMR 370 380 390 400 410 420 LLVDEHGLPW DDAWHVTTHT LGYTNHTLLP EALETWPVEL MERLLPRHMQ IIYLINWMHL 430 440 450 460 470 480 EGLSKHGKVD AGQLAAVSLI DEAHGKRVRM GHLAFLGARR VNGVSALHTE LMRQTVFAPL 490 500 510 520 530 540 HALDTDKIVN KTNGITFRRW FHNANPGLTR LSVEAVGARV LDDPTALEGL ARFAEDAAFQ 550 560 570 580 590 600 ERYAAVRRER KEALARVVKD RTGIAIDPAA LFDVQIKRIH EYKRQLLNIL ETVALYQAIL 610 620 630 640 650 660 AEPQRDWPAR VKLFAGKAAS SYHQAKLIIR LACDVAKRVN ADPVVAGRLQ VAFVPNYSVS 670 680 690 700 710 720 LAEAIIPAAD LSEQISTAGL EASGTGNMKL ALNGALTIGT LDGANIEIRE HVGDENIFIF 730 740 750 760 770 780 GLTAAGVQAT TAEPGYAARA IAASPRLKAA LDLIASGGFS PEEPHRFRPL VDELTGQDRY 790 800 810 820 830 LLTADFDDYW RVQREVDAAW RRPRTWWRAA ILNTARTAWF SSDRTMREYA EDIWRVEVA

References

[1]

"Complete sequence of chromosome of Methylobacterium nodulans ORS 2060." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ORS2060 / LMG 21967.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001349 Genomic DNA. Translation: ACL60113.1.
RefSeq	YP_002500416.1. NC_011894.1.
3D structure databases
ProteinModelPortal	B8ILB4.
ModBase	Search...
Protein-protein interaction databases
STRING	B8ILB4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7304248.
GenomeReviews	Gene locus Mnod_5267 in contig CP001349_GR.
KEGG	mno:Mnod_5267.
PATRIC	22552371. VBIMetNod76414_5881.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG444050.
OMA	LMKETVF.
ProtClustDB	CLSK2541622.
Family and domain databases
InterPro	IPR011833. Glycg_phsphrylas. IPR000811. Glyco_trans_35. [Graphical view]
KO	K00688.
PANTHER	PTHR11468. Glyco_trans_35. 1 hit.
Pfam	PF00343. Phosphorylase. 1 hit. [Graphical view]
PIRSF	PIRSF000460. Pprylas_GlgP. 1 hit.
TIGRFAMs	TIGR02093. P_ylase. 1 hit.
PROSITE	PS00102. PHOSPHORYLASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8ILB4_METNO

Accession

Primary (citable) accession number: B8ILB4

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)