B8IL42 (B8IL42_METNO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA topoisomerase IV, B subunit EMBL ACL58230.1
EC=5.99.1.3 EMBL ACL58230.1

Gene names

Ordered Locus Names:

Mnod_3307

Organism

Methylobacterium nodulans (strain ORS2060 / LMG 21967) [Complete proteome] [HAMAP]

Taxonomic identifier

460265 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length	684 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the type II topoisomerase family. RuleBase RU000380

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000380 SAAS SAAS002288 Nucleotide-binding
Molecular function	Isomerase Topoisomerase RuleBase RU000380 SAAS SAAS002288
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	DNA topological change Inferred from electronic annotation. Source: InterPro
Cellular component	chromosome Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA topoisomerase (ATP-hydrolyzing) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8IL42 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 1045ED3F5C8092C0	FASTA	684	74,610
	10 20 30 40 50 60 MNDAARDLFG PGAKPAPVDP IAGPKRPKPV AVPQPEPTPE AGYDASAIEV LEGLEPVRRR 70 80 90 100 110 120 PGMYIGGTDE KALHHLFAEV IDNAMDEAVA GHASFIEVEL AEGGILTVTD NGRGIPVDPH 130 140 150 160 170 180 PKFPGKSALE VIMTTLHAGG KFDSKVYETS GGLHGVGVSV VNALSDLLEV EVARKQILYR 190 200 210 220 230 240 QTFSRGLPQG GLEQVGPVQN RRGTKVRFHP DPQIFGALTF EPRRLFKMAR SKAYLFGGVE 250 260 270 280 290 300 IRWRCAPALL EGVANVPAEA VHRFPAGLKD YLAREIDGKE LVTDGLFTGK ITKPGSHGSL 310 320 330 340 350 360 EWAVAWLAND DGFSSSYCNT VPTPEGGTHE SGLRIALLRG LRDHAERVGQ VKRMQAVTTD 370 380 390 400 410 420 DVMATCAAML SVFIREPEFQ GQTKDKLATL EASRIVEAAV RDAFDHWLAA SPTQANRLLD 430 440 450 460 470 480 WVIDRAEERL RRRQEKEVAR KTATRKLRLP GKLADCSKAG AAGSEIFIVE GDSAGGSAKQ 490 500 510 520 530 540 ARDRATQAVL PLRGKILNVA SASRDKLGAN QLLSDLTQAL GCGTGAHYRE DDLRYEKVII 550 560 570 580 590 600 MTDADVDGAH IASLLITFFY RQMPRLIEKG HLYLAVPPLY RLTQGSKSAY ARDDRHKEQL 610 620 630 640 650 660 IKTVFKNGKV EIGRFKGLGE MMPGQLKETT MDPAKRTLLR VAVLEEAREA TGDTVERLMG 670 680 NKPEARFAFI SERAAFADEA ELDI

References

[1]

"Complete sequence of chromosome of Methylobacterium nodulans ORS 2060." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ORS2060 / LMG 21967.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001349 Genomic DNA. Translation: ACL58230.1.
RefSeq	YP_002498533.1. NC_011894.1.
3D structure databases
ProteinModelPortal	B8IL42.
ModBase	Search...
Protein-protein interaction databases
STRING	B8IL42.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7301732.
GenomeReviews	Gene locus Mnod_3307 in contig CP001349_GR.
KEGG	mno:Mnod_3307.
PATRIC	22548617. VBIMetNod76414_4032.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304889.
OMA	QARDKEF.
ProtClustDB	PRK05559.
Family and domain databases
InterPro	IPR003594. ATPase-like_ATP-bd. IPR020568. Ribosomal_S5_D2-typ_fold. IPR014721. Ribosomal_S5_D2-typ_fold_subgr. IPR001241. Topo_IIA. IPR013759. Topo_IIA_B/N_ab. IPR002288. Topo_IIA_B_C. IPR013506. Topo_IIA_bsu_dom2. IPR013760. Topo_IIA_cen. IPR018522. TopoIIA_CS. IPR005737. TopoIV_B_Gneg. IPR006171. Toprim_domain. [Graphical view]
Gene3D	G3DSA:3.30.565.10. ATP_bd_ATPase. 1 hit. G3DSA:3.30.230.10. Ribosomal_S5_D2-type_fold. 1 hit. G3DSA:3.40.50.670. Topo_IIA_B/N_ab. 1 hit.
KO	K02622.
Pfam	PF00204. DNA_gyraseB. 1 hit. PF00986. DNA_gyraseB_C. 1 hit. PF02518. HATPase_c. 1 hit. PF01751. Toprim. 1 hit. [Graphical view]
PRINTS	PR00418. TPI2FAMILY.
SMART	SM00387. HATPase_c. 1 hit. SM00433. TOP2c. 1 hit. [Graphical view]
SUPFAM	SSF55874. ATP_bd_ATPase. 1 hit. SSF54211. Ribosomal_S5_D2-typ_fold. 1 hit. SSF56719. Topo_IIA_cen. 1 hit.
TIGRFAMs	TIGR01055. ParE_Gneg. 1 hit.
PROSITE	PS00177. TOPOISOMERASE_II. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8IL42_METNO

Accession

Primary (citable) accession number: B8IL42

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)