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B8IHV2 (B8IHV2_METNO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Mannonate dehydratase HAMAP MF_00106

EC=4.2.1.8 HAMAP MF_00106
Alternative name(s):
D-mannonate hydrolase HAMAP MF_00106
Gene names
Name:uxuA HAMAP MF_00106
Ordered Locus Names:Mnod_0977
OrganismMethylobacterium nodulans (strain ORS2060 / LMG 21967) [Complete proteome] [HAMAP]
Taxonomic identifier460265 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H2O. HAMAP MF_00106 SAAS SAAS004628

Pathway

Carbohydrate metabolism; pentose and glucuronate interconversion. HAMAP MF_00106 SAAS SAAS004628

Sequence similarities

Belongs to the mannonate dehydratase family. HAMAP MF_00106

Ontologies

Keywords
   Molecular functionLyase HAMAP MF_00106 SAAS SAAS004628 EMBL ACL55990.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processglucuronate catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionmannonate dehydratase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B8IHV2 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: A361B24927721EBF

FASTA39843,296
        10         20         30         40         50         60 
MEQTWRWFGP DDCVRLADAR QAGATGIVTA LHHIPYGEVW SIAEIERRKA EIGADPSLGL 

        70         80         90        100        110        120 
RWSVVESLPV HERIKLGEGD LEPLFAAYRA SLRNLAACGI TTICYNFMPV LDWTRTELAH 

       130        140        150        160        170        180 
PLPGGGTALR FNAHEFAAFD CFMLARPGAE ADHPPEALAR GRAWFTRSSE ADRAKLLATI 

       190        200        210        220        230        240 
MAGLPGAFDR YDIAGLRRML DRYRGIDTNT LRGNLAAFLR AVIPTAAEVG IRMAIHPDDP 

       250        260        270        280        290        300 
PRPLMGLPRI VSNADDLAFI TGAVDAEANG ITLCSGSLGA GPANDVPALA RRFAHRIHFA 

       310        320        330        340        350        360 
HLRNVAKEPD GSFMEADHLG GDTDMVALID ALLAEQERRR AAGDPRWRIP MRPDHGHALL 

       370        380        390 
SDIGQGAFPG YTAVGRLKGL AELRGVMTAL ASLRGWEL 

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References

[1]"Complete sequence of chromosome of Methylobacterium nodulans ORS 2060."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ORS2060 / LMG 21967.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001349 Genomic DNA. Translation: ACL55990.1.
RefSeqYP_002496293.1. NC_011894.1.

3D structure databases

ProteinModelPortalB8IHV2.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8IHV2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7302520.
GenomeReviewsGene locus Mnod_0977 in contig CP001349_GR.
KEGGmno:Mnod_0977.
PATRIC22544160. VBIMetNod76414_1820.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG585927.
OMAVHEEIKT.
ProtClustDBCLSK855552.

Family and domain databases

HAMAPMF_00106. UxuA.
[Tree]
InterProIPR004628. Man_deHydtase.
IPR013022. Xyl_isomerase-like_TIM-brl.
[Graphical view]
Gene3DG3DSA:3.20.20.150. Xyl_isomerase-like_TIM-brl. 1 hit.
KOK01686.
PfamPF03786. UxuA. 1 hit.
[Graphical view]
PIRSFPIRSF016049. Man_dehyd. 1 hit.
SUPFAMSSF51658. Xyl_isomerase-like_TIM-brl. 1 hit.
TIGRFAMsTIGR00695. UxuA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8IHV2_METNO
AccessionPrimary (citable) accession number: B8IHV2
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)