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B8IGX9 (B8IGX9_METNO) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209
Gene names
Name:ppa HAMAP MF_00209
Ordered Locus Names:Mnod_2903
OrganismMethylobacterium nodulans (strain ORS2060 / LMG 21967) [Complete proteome] [HAMAP]
Taxonomic identifier460265 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium

Protein attributes

Sequence length177 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209

Subcellular location

Cytoplasm By similarity HAMAP MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP MF_00209
   LigandMagnesium HAMAP MF_00209
Metal-binding HAMAP MF_00209
   Molecular functionHydrolase HAMAP MF_00209 EMBL ACL57854.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphate-containing compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioninorganic diphosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding661Magnesium 1 By similarity HAMAP MF_00209
Metal binding711Magnesium 1 By similarity HAMAP MF_00209
Metal binding711Magnesium 2 By similarity HAMAP MF_00209
Metal binding1031Magnesium 1 By similarity HAMAP MF_00209

Sequences

Sequence LengthMass (Da)Tools
B8IGX9 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 8AC9FB8EF26D5468

FASTA17719,806
        10         20         30         40         50         60 
MRLDAVAIGK NPPEDVNVVI EVPVGGEPIK YEMDKDAGTL IVDRFLYTAM HYPGNYGFIP 

        70         80         90        100        110        120 
HTLSGDGDPC DVLIANTRAI VPGAIMSVRP VGVLVMEDNA GEDEKIVAVP SRHLTKRYDR 

       130        140        150        160        170 
VENYTDLPDI TLHQIQHFFE HYKDLEPGKW VKIVRWGDKA EAQRLIVEGI ERAKSKA

« Hide

References

[1]"Complete sequence of chromosome of Methylobacterium nodulans ORS 2060."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ORS2060 / LMG 21967.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001349 Genomic DNA. Translation: ACL57854.1.
RefSeqYP_002498157.1. NC_011894.1.

3D structure databases

ProteinModelPortalB8IGX9.
SMRB8IGX9. Positions 3-174.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8IGX9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7304075.
GenomeReviewsGene locus Mnod_2903 in contig CP001349_GR.
KEGGmno:Mnod_2903.
PATRIC22547922. VBIMetNod76414_3686.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG529150.
OMAPNDFNVI.
ProtClustDBPRK01250.

Family and domain databases

HAMAPMF_00209. Inorganic_PPase.
[Tree]
InterProIPR008162. Pyrophosphatase.
[Graphical view]
Gene3DG3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KOK01507.
PANTHERPTHR10286. Pyrophosphatase. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8IGX9_METNO
AccessionPrimary (citable) accession number: B8IGX9
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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