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Protein
Submitted name:

NAD synthase

Gene

Mnod_2890

Organism
Methylobacterium nodulans (strain ORS2060 / LMG 21967)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds Source: InterPro
  3. NAD+ synthase (glutamine-hydrolyzing) activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciMNOD460265:GCZK-2916-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
NAD synthaseImported
Gene namesi
Ordered Locus Names:Mnod_2890Imported
OrganismiMethylobacterium nodulans (strain ORS2060 / LMG 21967)Imported
Taxonomic identifieri460265 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesMethylobacteriaceaeMethylobacterium
ProteomesiUP000008207 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi460265.Mnod_2890.

Structurei

3D structure databases

ProteinModelPortaliB8IGW6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0388.
HOGENOMiHOG000051304.
KOiK01950.
OMAiWRAPSDG.
OrthoDBiEOG6VB6S8.

Family and domain databases

Gene3Di3.40.50.620. 2 hits.
3.60.110.10. 1 hit.
InterProiIPR003010. C-N_Hydrolase.
IPR014445. Gln-dep_NAD_synthase.
IPR022310. NAD/GMP_synthase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00795. CN_hydrolase. 1 hit.
PF02540. NAD_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF006630. NADS_GAT. 1 hit.
SUPFAMiSSF56317. SSF56317. 1 hit.
PROSITEiPS50263. CN_HYDROLASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8IGW6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRSLYQHGF ARVAACVGQS HIAEPAANVA EVLALARRCH DQGVAVAVFP
60 70 80 90 100
ELCLSAYAIE DLLLQETLLD GVEAAVATLA EGTRDLLPLL VVGAPLRHGH
110 120 130 140 150
RVYNTAVMLH RGRVLGVVPK SYLPNYREFY EKRHFAPGAG ITGETIRLAG
160 170 180 190 200
AAIPFGTDLL FAAEDLPGLV IGVDVCEDMW IPVPPGALAA LAGATVLVNL
210 220 230 240 250
SGSPITIGRA ESRKLLCQSS SVRCLSAYIY AAAGPGESTT DLAWDGQTAI
260 270 280 290 300
YEDGTLLAES ERFPDGPQVT VADIDLDRLR QERAQMGSFD DNARAVLGER
310 320 330 340 350
PWRRIAFTVA PPRHDLGLAR TVERFPFVPA DPARLAQDCY EGYNIQVAGL
360 370 380 390 400
AQRLRAIRTS KVVIGISGGL DSTHALIVAA KAFDRLGLPR TNILTYTMPG
410 420 430 440 450
FATSAETKGN AHRLMASLGT TATELDIRPA ARQMLTDMGH PFGRGEPVYD
460 470 480 490 500
VTFENVQAGL RTDFLFRLAN QNDAIVVGTG DLSELALGWC TYGVGDQMSH
510 520 530 540 550
YAVNAGVPKT LIQHLIRWVV SSGQFDAAVN RTLEAILATE ISPELVPVEE
560 570 580 590 600
GGQIQSTEAR IGPYALQDFN LFYTLRFGYR PSKIAFLACH AWEDASRGPW
610 620 630 640 650
PPGFPDERRG AYALPEIRAW LKVFLRRFFG FSQFKRSALP NGPKVAAGGA
660 670
LSPRGDWRAP SDGNAAAWLA ELERNVPEA
Length:679
Mass (Da):73,496
Last modified:March 3, 2009 - v1
Checksum:iD8C386F5B930D769
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001349 Genomic DNA. Translation: ACL57841.1.
RefSeqiWP_015929516.1. NC_011894.1.
YP_002498144.1. NC_011894.1.

Genome annotation databases

EnsemblBacteriaiACL57841; ACL57841; Mnod_2890.
GeneIDi7304062.
KEGGimno:Mnod_2890.
PATRICi22547884. VBIMetNod76414_3665.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001349 Genomic DNA. Translation: ACL57841.1.
RefSeqiWP_015929516.1. NC_011894.1.
YP_002498144.1. NC_011894.1.

3D structure databases

ProteinModelPortaliB8IGW6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi460265.Mnod_2890.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACL57841; ACL57841; Mnod_2890.
GeneIDi7304062.
KEGGimno:Mnod_2890.
PATRICi22547884. VBIMetNod76414_3665.

Phylogenomic databases

eggNOGiCOG0388.
HOGENOMiHOG000051304.
KOiK01950.
OMAiWRAPSDG.
OrthoDBiEOG6VB6S8.

Enzyme and pathway databases

BioCyciMNOD460265:GCZK-2916-MONOMER.

Family and domain databases

Gene3Di3.40.50.620. 2 hits.
3.60.110.10. 1 hit.
InterProiIPR003010. C-N_Hydrolase.
IPR014445. Gln-dep_NAD_synthase.
IPR022310. NAD/GMP_synthase.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00795. CN_hydrolase. 1 hit.
PF02540. NAD_synthase. 1 hit.
[Graphical view]
PIRSFiPIRSF006630. NADS_GAT. 1 hit.
SUPFAMiSSF56317. SSF56317. 1 hit.
PROSITEiPS50263. CN_HYDROLASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of chromosome of Methylobacterium nodulans ORS 2060."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J., Richardson P.
    Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ORS2060 / LMG 21967Imported.

Entry informationi

Entry nameiB8IGW6_METNO
AccessioniPrimary (citable) accession number: B8IGW6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 1, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.