B8ID24 (GLMM_METNO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Mnod_4549

Organism

Methylobacterium nodulans (strain ORS2060 / LMG 21967) [Complete proteome] [HAMAP]

Taxonomic identifier

460265 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Methylobacteriaceae › Methylobacterium › Methylobacterium nodulans

Protein attributes

Sequence length	446 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP-Rule MF_01554
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP-Rule MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_01554
Post-translational modification	Activated by phosphorylation By similarity. HAMAP-Rule MF_01554
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	magnesium ion binding Inferred from electronic annotation. Source: HAMAP phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 446	446	Phosphoglucosamine mutase HAMAP-Rule MF_01554		PRO_1000185374
Sites
	Active site	100	1	Phosphoserine intermediate By similarity
	Metal binding	100	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	100	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B8ID24 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: FB6CA97FE1BCA83C	FASTA	446	48,537
	10 20 30 40 50 60 MRKYFGTDGI RGRANGVITP ELALKVGQAA GLLFQRGEYR HRVVIGKDTR LSGYMIETAL 70 80 90 100 110 120 VAGFTSVGMD VLLLGPMPTP AVAMLTRSMR ADLGVMISAS HNPYEDNGIK LFGPDGFKLS 130 140 150 160 170 180 DEVEHEIERL IDSDLQKRLS ASADLGRAKR IESVHARYIE FAKRTLPRNI TLDGLRVVVD 190 200 210 220 230 240 CANGAAYRVA PETLWELGAE VIAIGTEPDG FNINRDVGST APDALVRKVR ELRADIGIAL 250 260 270 280 290 300 DGDADRVLVV DEKGQRVDGD QLMAVVARSW KEDERLTQPG IVATIMSNLG LERYLGGLGL 310 320 330 340 350 360 SLVRTAVGDR YVLEHMREHG YNLGGEQSGH IIMSDYATTG DGLVAALQLL TVVQRQKRPV 370 380 390 400 410 420 SEVCHCFDPL PQVLKNVRYG AGEPLRKDSV VTAIEGARQR LGNAGRLVIR PSGTEPVIRV 430 440 MAEGDDRDLV VEVVDEVVEA LRKAAA

References

[1]

"Complete sequence of chromosome of Methylobacterium nodulans ORS 2060." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Marx C.J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ORS2060 / LMG 21967.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001349 Genomic DNA. Translation: ACL59416.1.
RefSeq	YP_002499719.1. NC_011894.1.
3D structure databases
ProteinModelPortal	B8ID24.
ModBase	Search...
Protein-protein interaction databases
STRING	460265.Mnod_4549.
Proteomic databases
PRIDE	B8ID24.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACL59416; ACL59416; Mnod_4549.
GeneID	7303645.
KEGG	mno:Mnod_4549.
PATRIC	22550924. VBIMetNod76414_5166.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HOG000268678.
KO	K03431.
OMA	TLMSNMS.
ProtClustDB	PRK14315.
Enzyme and pathway databases
BioCyc	MNOD460265:GCZK-4594-MONOMER.
Family and domain databases
Gene3D	3.40.120.10. 3 hits.
HAMAP	MF_01554_B. GlmM_B.
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 2 hits.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_METNO

Accession

Primary (citable) accession number: B8ID24

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	May 29, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program