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B8I0V0

- TRPC_CLOCE

UniProt

B8I0V0 - TRPC_CLOCE

Protein

Indole-3-glycerol phosphate synthase

Gene

trpC

Organism
Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. indole-3-glycerol-phosphate synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. tryptophan biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

    Enzyme and pathway databases

    BioCyciCCEL394503:GJET-3282-MONOMER.
    UniPathwayiUPA00035; UER00043.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Indole-3-glycerol phosphate synthaseUniRule annotation (EC:4.1.1.48UniRule annotation)
    Short name:
    IGPSUniRule annotation
    Gene namesi
    Name:trpCUniRule annotation
    Ordered Locus Names:Ccel_3216
    OrganismiClostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10)
    Taxonomic identifieri394503 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesClostridiaceaeClostridium
    ProteomesiUP000001349: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 260260Indole-3-glycerol phosphate synthasePRO_1000198771Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi394503.Ccel_3216.

    Structurei

    3D structure databases

    ProteinModelPortaliB8I0V0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the TrpC family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0134.
    HOGENOMiHOG000230462.
    KOiK01609.
    OMAiENGAAMI.
    OrthoDBiEOG6WT8JX.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00134_B. IGPS_B.
    InterProiIPR013785. Aldolase_TIM.
    IPR013798. Indole-3-glycerol_P_synth.
    IPR001468. Indole-3-GlycerolPSynthase_CS.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PfamiPF00218. IGPS. 1 hit.
    [Graphical view]
    SUPFAMiSSF51366. SSF51366. 1 hit.
    PROSITEiPS00614. IGPS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8I0V0-1 [UniParc]FASTAAdd to Basket

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    MILDKIAAST KIRVENLKKE VSFSFVKSEA SKLVNKSPFA FEKAVKDGEL    50
    TFICEIKKAS PSKGLISENF PYIDIAKDYE AAGAGAISVL TEPEFFLGSD 100
    QYLKDVKKTV SIPVLRKDFT IDPYQIYEAA LIGADCVLLI CALLDTDTLK 150
    EYIKIADGLG LSCLVEAHDE NEVKSAIEAG SRIVGVNNRN LKTFEVDITN 200
    SIRLRELVPS DISFVSESGI RTAQDISALR RIGASAVLIG ETLMRSGDTG 250
    AELAKLRGSA 260
    Length:260
    Mass (Da):28,230
    Last modified:March 3, 2009 - v1
    Checksum:i89176A0C3025A9F0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001348 Genomic DNA. Translation: ACL77506.1.
    RefSeqiWP_015926564.1. NC_011898.1.
    YP_002507486.1. NC_011898.1.

    Genome annotation databases

    EnsemblBacteriaiACL77506; ACL77506; Ccel_3216.
    GeneIDi7311798.
    KEGGicce:Ccel_3216.
    PATRICi19437437. VBICloCel57783_3296.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001348 Genomic DNA. Translation: ACL77506.1 .
    RefSeqi WP_015926564.1. NC_011898.1.
    YP_002507486.1. NC_011898.1.

    3D structure databases

    ProteinModelPortali B8I0V0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 394503.Ccel_3216.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACL77506 ; ACL77506 ; Ccel_3216 .
    GeneIDi 7311798.
    KEGGi cce:Ccel_3216.
    PATRICi 19437437. VBICloCel57783_3296.

    Phylogenomic databases

    eggNOGi COG0134.
    HOGENOMi HOG000230462.
    KOi K01609.
    OMAi ENGAAMI.
    OrthoDBi EOG6WT8JX.

    Enzyme and pathway databases

    UniPathwayi UPA00035 ; UER00043 .
    BioCyci CCEL394503:GJET-3282-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00134_B. IGPS_B.
    InterProi IPR013785. Aldolase_TIM.
    IPR013798. Indole-3-glycerol_P_synth.
    IPR001468. Indole-3-GlycerolPSynthase_CS.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    Pfami PF00218. IGPS. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51366. SSF51366. 1 hit.
    PROSITEi PS00614. IGPS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 35319 / DSM 5812 / JCM 6584 / H10.

    Entry informationi

    Entry nameiTRPC_CLOCE
    AccessioniPrimary (citable) accession number: B8I0V0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3