B8I0I6 (GLMM_CLOCE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	Ccel_1204

Organism

Clostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) [Complete proteome] [HAMAP]

Taxonomic identifier

394503 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	449 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 449	449	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_1000185360
Sites
	Active site	101	1	Phosphoserine intermediate By similarity
	Metal binding	101	1	Magnesium; via phosphate group By similarity
	Metal binding	241	1	Magnesium By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
Amino acid modifications
	Modified residue	101	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	B8I0I6 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 2152609A7F912EF6	FASTA	449	48,690
	10 20 30 40 50 60 MGRLFGTDGV RGVANLELTP KLAYQLGQAG AYVLTGETKH TPKILVGMDT RISGDMLEAA 70 80 90 100 110 120 LISGICSVGA QVVSLGVIPT PAIAYLTRQY DADAGVVISA SHNPFEYNGI KFFNSNGYKL 130 140 150 160 170 180 PDAIEDKIEE IIQNGGEDLP KPVGQNIGFK CYQENALEDY VNFVKGTITG DFEGIKVAID 190 200 210 220 230 240 CANGASFQAA PMALFDLKAD VSVINNEPDG TNINSGCGST HMRQLQAYVK EIKADIGFAF 250 260 270 280 290 300 DGDADRVLAV DENGNIVDGD QIMAIIGLYL KDKGILSQNT IVATVMSNMG LDIMAKNKGL 310 320 330 340 350 360 TIEKTKVGDR YVLEEMLNKG YMLGGEQSGH IIFLDHNTTG DGLLTAVQLL KVLKDSGKKL 370 380 390 400 410 420 SELAGVMEIL PQVLINAKVT NEKKYKYLDD EVIKKMCKEL EDEFKGEGRV LIRPSGTEPL 430 440 VRVMIEGKDK DIITRRAKEL VRVIEGRLS

References

[1]

"Complete sequence of Clostridium cellulolyticum H10." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Saunders E., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. , Ivanova N., Zhou J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 35319 / DSM 5812 / JCM 6584 / H10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001348 Genomic DNA. Translation: ACL75561.1.
RefSeq	YP_002505541.1. NC_011898.1.
3D structure databases
ProteinModelPortal	B8I0I6.
ModBase	Search...
Protein-protein interaction databases
STRING	B8I0I6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7310004.
GenomeReviews	Gene locus Ccel_1204 in contig CP001348_GR.
KEGG	cce:Ccel_1204.
PATRIC	19433241. VBICloCel57783_1243.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG644964.
OMA	GVGSTHL.
ProtClustDB	PRK14316.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 2 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_CLOCE

Accession

Primary (citable) accession number: B8I0I6

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program