ID   B8HWB1_CYAP4            Unreviewed;       884 AA.
AC   B8HWB1;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 68.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with FHA and GAF sensor {ECO:0000313|EMBL:ACL44690.1};
GN   OrderedLocusNames=Cyan7425_2332 {ECO:0000313|EMBL:ACL44690.1};
OS   Cyanothece sp. (strain PCC 7425 / ATCC 29141).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Gomontiellales; Cyanothecaceae;
OC   Cyanothece.
OX   NCBI_TaxID=395961 {ECO:0000313|EMBL:ACL44690.1};
RN   [1] {ECO:0000313|EMBL:ACL44690.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC 7425 {ECO:0000313|EMBL:ACL44690.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L.,
RA   Sato H., Zhao L., Sherman L., Pakrasi H., Richardson P.;
RT   "Complete sequence of chromosome Cyanothece sp. PCC 7425.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001344; ACL44690.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8HWB1; -.
DR   STRING; 395961.Cyan7425_2332; -.
DR   KEGG; cyn:Cyan7425_2332; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 431840at2; -.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50887; GGDEF; 1.
PE   4: Predicted;
FT   DOMAIN          31..91
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   DOMAIN          478..611
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          620..874
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   884 AA;  99326 MW;  7794E7CD637E5ABD CRC64;
     MIQQQVPPIR HLLVVEDNLG RRSILLDADT YSLGRSSGNA IVVHSALVSR QHAMLLRVDK
     SDSESQRFRI VDGNLLGNRS TNGLFINGQR CLSHDLKHGD VIEFGVEAKA QYLSTVNLSD
     AEVLAYVQAV SPPTNPVSEF AKTTVIADPA LLLQPQSERP ELIARLASFP ELFPYPILEV
     DRFGNITYLN PAAVETFPNL QSKGQEHPLL IGLLQVIQEH PHSFCTRQVQ VGNTFFEQSI
     HYLPASNLIR CFAIDITQRL QAERELYLRD RLLQAVTTAT HHLLTNSDFE TAVPHALATL
     GAAAEVERVY IYDNRYCLIN REPAMQLRFV WQADSFTVHE DNHRQSPAFS SFSLSHWYDH
     LAEGKTISGL TNSFSPQEQD ILNRAGIKSL LIVPILVDDQ LWGCIGFDAC QSSRCWSKNE
     EAVLAMMAVS ISGAIQRQHK EQVIRYQAFH DLLTDLPNRA LFIDRLNLAL SNAHRSGEKL
     SVLFLDLDRF KTINDTLGHS VGDQLLKAVA HRLTHCLREG DTIARWGGDE FTILLPQIHQ
     VNDVAKTAQR MLSALEQPFH LENHELYITP SIGIAIYDLD GHDGETLIKH ADMALYQAKQ
     LGRNTYQFFC SGLSNGAPER LNLEKSLRHA LERQEFLLYY QPQVNIKTGK ITGMEALLRW
     KHPEMGLVIP QLFMSVAEES GLIVAIGEWV LRTACAQNKT WQDQGLPPIC IAVNLSARQF
     RQPDLTGMIA RILDETGLPP QYLDLEITET TAIQDIEFTK RVLQELQDMG IQISMDDFGT
     GYSSLAHLQQ FPLNTLKIDR SFVRDVAANS RDAQIVTAVI GLARGLNLNV VAEGVENDEQ
     LNCLESLHCE EAQGYIFNRP LEADAATEIL QLNSFQLQKL QRHE
//