B8HW27 (COMB_CYAP4) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	Cyan7425_0819

Organism

Cyanothece sp. (strain PCC 7425 / ATCC 29141) [Complete proteome] [HAMAP]

Taxonomic identifier

395961 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length	244 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity. HAMAP MF_00490
Sequence similarities	Belongs to the ComB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: EC magnesium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 244	244	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_1000189625

Sequences

	Sequence		Length	Mass (Da)
	B8HW27 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 480F1B935B92EA98	FASTA	244	26,406
	10 20 30 40 50 60 MKIFVYYTPE RVPDGTVAEC AIAVDVLRAT TTIATALAAG AEAIQVFSDL DKLIATSATW 70 80 90 100 110 120 PAERCIRVGE RGGKTVDGFD MGNSPFDCTP ERVKACRLFM STTNGTRSLQ RIESAKTVIA 130 140 150 160 170 180 AALVNREAVA KFIYTQQPET VWIVGSGWEG SYSLEDTVCA GAIAHSLLLA TGIPLEDLAG 190 200 210 220 230 240 NDETIAAIAL YRSYREDLLS LLQQASHGKR LLNLNCHEDL KYCSQTDILD VLPVQQQPGV LVAH

References

[1]

"Complete sequence of chromosome Cyanothece sp. PCC 7425." US DOE Joint Genome Institute Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. , Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L., Sato H., Zhao L., Sherman L., Pakrasi H.B., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 7425 / ATCC 29141.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001344 Genomic DNA. Translation: ACL43205.1.
RefSeq	YP_002481566.1. NC_011884.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	B8HW27.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7286735.
GenomeReviews	Gene locus Cyan7425_0819 in contig CP001344_GR.
KEGG	cyn:Cyan7425_0819.
PATRIC	21562557. VBICyaSp30657_0806.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG633644.
OMA	DFICSGY.
PhylomeDB	B8HW27.
Family and domain databases
HAMAP	MF_00490. ComB. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. IPR022995. Pase_ComB. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
KO	K05979.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
SUPFAM	SSF142823. SSF142823. 1 hit.
ProtoNet	Search...

Entry information

Entry name

COMB_CYAP4

Accession

Primary (citable) accession number: B8HW27

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 28, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program