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Protein

16S rRNA (cytosine(967)-C(5))-methyltransferase

Gene

Cyan7425_0682

Organism
Cyanothece sp. (strain PCC 7425 / ATCC 29141)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.SAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(967) in 16S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(967) in 16S rRNA.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei285S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei312S-adenosyl-L-methioninePROSITE-ProRule annotation1
Binding sitei328S-adenosyl-L-methioninePROSITE-ProRule annotation1
Active sitei381NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferasePROSITE-ProRule annotationSAAS annotation, RNA-bindingPROSITE-ProRule annotationSAAS annotation, Transferase
Biological processrRNA processingSAAS annotation
LigandS-adenosyl-L-methioninePROSITE-ProRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciCSP395961:GJDE-482-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
16S rRNA (cytosine(967)-C(5))-methyltransferaseSAAS annotation (EC:2.1.1.176SAAS annotation)
Gene namesi
Ordered Locus Names:Cyan7425_0682Imported
OrganismiCyanothece sp. (strain PCC 7425 / ATCC 29141)Imported
Taxonomic identifieri395961 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesCyanothecaceaeCyanothece
Proteomesi
  • UP000002511 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm SAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi395961.Cyan7425_0682

Structurei

3D structure databases

ProteinModelPortaliB8HV23
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini170 – 443SAM_MT_RSMB_NOPInterPro annotationAdd BLAST274

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni261 – 267S-adenosyl-L-methionine bindingPROSITE-ProRule annotation7

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.PROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CYJ Bacteria
COG0144 LUCA
HOGENOMiHOG000037300
KOiK03500
OMAiLRVNRQH
OrthoDBiPOG091H02E2

Family and domain databases

Gene3Di1.10.940.10, 1 hit
InterProiView protein in InterPro
IPR001678 MeTrfase_RsmB/NOP2
IPR035926 NusB-like_sf
IPR006027 NusB_RsmB_TIM44
IPR023267 RCMT
IPR004573 rRNA_ssu_MeTfrase_B
IPR029063 SAM-dependent_MTases
PfamiView protein in Pfam
PF01189 Methyltr_RsmB-F, 1 hit
PF01029 NusB, 1 hit
PRINTSiPR02008 RCMTFAMILY
SUPFAMiSSF48013 SSF48013, 1 hit
SSF53335 SSF53335, 1 hit
TIGRFAMsiTIGR00563 rsmB, 1 hit
PROSITEiView protein in PROSITE
PS51686 SAM_MT_RSMB_NOP, 1 hit

Sequencei

Sequence statusi: Complete.

B8HV23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNARQLAFIT LQAVHRGAYA DVAVERSLRQ HPLTEERERR LATELVYGCV
60 70 80 90 100
RRQRTLDALV DQLAKKPARQ QPPDLRTLLH LGLYQLRYLN HIPANAAVHT
110 120 130 140 150
TVELVKHRGL AGLAGFVNGL LRQYIRQSAG GDPLSLPTDP VQQLALLHSY
160 170 180 190 200
PDWIVANWME QIGTTETDQL CQWLNRPPSI DLRINPLQTS IEQVGSAFQS
210 220 230 240 250
AGVSVQPLAG LPQGLRLTEP SGAIEQLPGF AQGWWSVQDA SAQLVSHLLN
260 270 280 290 300
PQPGEVIIDA CAAPGGKSTH IAELIGDKGI VWACDRTPSR LKKLEQNRQR
310 320 330 340 350
LKLNSIRICQ GDSRMSEFTA QADRVLLDAP CSGLGTLHRH ADARWRQTPE
360 370 380 390 400
SVAQLAQLQT ELLHHTATWV KPGGTLVYAT CTLHPTENEA VIQQFLAHHP
410 420 430 440
QWQIQAPRHP PFSADWLAPQ GWIKVWPHRH QMDGFFMVRL GRS
Length:443
Mass (Da):49,419
Last modified:March 3, 2009 - v1
Checksum:i6713493C91E98BCE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001344 Genomic DNA Translation: ACL43070.1
RefSeqiWP_012626168.1, NC_011884.1

Genome annotation databases

EnsemblBacteriaiACL43070; ACL43070; Cyan7425_0682
KEGGicyn:Cyan7425_0682

Similar proteinsi

Entry informationi

Entry nameiB8HV23_CYAP4
AccessioniPrimary (citable) accession number: B8HV23
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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