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B8HUP8 (B8HUP8_CYAP4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Biosynthetic arginine decarboxylase HAMAP MF_01417
Short name=ADC HAMAP MF_01417
EC=4.1.1.19 HAMAP MF_01417
Gene names
Name:speA HAMAP MF_01417
Ordered Locus Names:Cyan7425_3934
OrganismCyanothece sp. (strain PCC 7425 / ATCC 29141) [Complete proteome] [HAMAP] EMBL ACL46250.1
Taxonomic identifier395961 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length655 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the biosynthesis of agmatine from arginine By similarity. HAMAP MF_01417 SAAS SAAS009006

Catalytic activity

L-arginine = agmatine + CO2. HAMAP MF_01417 SAAS SAAS009006

Cofactor

Magnesium By similarity. HAMAP MF_01417 SAAS SAAS009006

Pyridoxal phosphate By similarity. HAMAP MF_01417 SAAS SAAS000183

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1. HAMAP MF_01417

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily. HAMAP MF_01417

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region307 – 31711Substrate-binding By similarity HAMAP MF_01417

Amino acid modifications

Modified residue1251N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01417

Sequences

Sequence LengthMass (Da)Tools
B8HUP8 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 38472F321E2514B1

FASTA65573,753
        10         20         30         40         50         60 
MGVELRAKRP KRQAEEQEAA VAPGNKQSWT IEDSENLYRI QGWGDPYFSI NAAGHVTVSP 

        70         80         90        100        110        120 
KGDRGGSLDL FELVNALKLR NIGLPLLLRF TDILEDRIER LNACFAKAIA RYNYAGNYRG 

       130        140        150        160        170        180 
VFPVKCNQQR HLIEDLVRFG KPHQFGLEAG SKPELLIALA TLNTPGALMI CNGYKDREYI 

       190        200        210        220        230        240 
ETAILARRLG QTCIIVLEQI EEIPLVIAIS RRLGIEPILG VRAKLSTKGI GRWGTSAGDR 

       250        260        270        280        290        300 
AKFGLTVPEI LTAVEELRSA GMLHCLQLLH FHIGSQISAI GVIKDALREA SQIYVELVRL 

       310        320        330        340        350        360 
GAKMQYLDVG GGLGVDYDGS KTNFHASKNY SMQNYANDVV AEIKEACAAR QLPVPTLISE 

       370        380        390        400        410        420 
SGRAIASHQS VLIFDVLGTS EILSTEPEPA QDEDHSIIRE LYDTYLNIST DNYQEAYNDA 

       430        440        450        460        470        480 
LQFKEEATSL FNFAHLSLTE RARVEKLFWN CCARILTIAR QQEYVPDDLE DLERIMASIY 

       490        500        510        520        530        540 
YINLSVFQSV PDSWAIDQLF PIMPIHRLDE EPTQRAILAD LTCDSDGKID QFIDLRDVKS 

       550        560        570        580        590        600 
VLELHPLQPG QPYYLGLFLS GAYQEIMGNL HNLFGDTNAV HIHLTPKGYQ LEHVVRGDTM 

       610        620        630        640        650 
REVLGYVQYD AEDLLENIRR QCENALEEDQ ITLEESQRLL ENYERSLRSY TYLAD

« Hide

References

[1]"Complete sequence of chromosome Cyanothece sp. PCC 7425."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L., Sato H., Zhao L., Sherman L., Pakrasi H.B., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7425 / ATCC 29141.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001344 Genomic DNA. Translation: ACL46250.1.
RefSeqYP_002484611.1. NC_011884.1.

3D structure databases

ProteinModelPortalB8HUP8.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8HUP8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7289880.
GenomeReviewsGene locus Cyan7425_3934 in contig CP001344_GR.
KEGGcyn:Cyan7425_3934.
PATRIC21568821. VBICyaSp30657_3906.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG321436.
OMALICNGYK.
PhylomeDBB8HUP8.
ProtClustDBPRK05354.

Family and domain databases

HAMAPMF_01417. SpeA.
[Tree]
InterProIPR009006. Ala_racemase/Decarboxylase_C.
IPR002985. Arg_decrbxlase.
IPR022643. De-COase2_C.
IPR022657. De-COase2_CS.
IPR022644. De-COase2_N.
IPR022653. De-COase2_pyr-phos_BS.
IPR000183. Orn/DAP/Arg_de-COase.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 2 hits.
KOK01585.
PANTHERPTHR11482:SF3. Arg_decrbxlase. 1 hit.
PfamPF02784. Orn_Arg_deC_N. 1 hit.
PF00278. Orn_DAP_Arg_deC. 1 hit.
[Graphical view]
PIRSFPIRSF001336. Arg_decrbxlase. 1 hit.
PRINTSPR01180. ARGDCRBXLASE.
PR01179. ODADCRBXLASE.
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR01273. SpeA. 1 hit.
PROSITEPS00878. ODR_DC_2_1. 1 hit.
PS00879. ODR_DC_2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8HUP8_CYAP4
AccessionPrimary (citable) accession number: B8HUP8
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info