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B8HUK2 (B8HUK2_CYAP4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A synthetase HAMAP MF_01123
EC=6.2.1.1 HAMAP MF_01123
Alternative name(s):
Acetate--CoA ligase HAMAP MF_01123
Acyl-activating enzyme HAMAP MF_01123
Gene names
Name:acsA HAMAP MF_01123
Ordered Locus Names:Cyan7425_3887
OrganismCyanothece sp. (strain PCC 7425 / ATCC 29141) [Complete proteome] [HAMAP] EMBL ACL46204.1
Taxonomic identifier395961 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length657 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA. HAMAP MF_01123

Post-translational modification

Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme By similarity. HAMAP MF_01123

Sequence similarities

Belongs to the ATP-dependent AMP-binding enzyme family. HAMAP MF_01123

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site5301 By similarity HAMAP MF_01123

Amino acid modifications

Modified residue6221N6-acetyllysine By similarity HAMAP MF_01123

Sequences

Sequence LengthMass (Da)Tools
B8HUK2 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: B86531E190E6310F

FASTA65772,897
        10         20         30         40         50         60 
MPQAAIESIL QEKRLFYPAP EFAQKAHIQT LEQYQQLCDR AKQDPLAFWA ELAQTELHWF 

        70         80         90        100        110        120 
SDWQQVLDWQ PPFAKWFVGG KTNIAYNCLD RHLTTARRNK AALIWEGEPG DSRTLTYAQL 

       130        140        150        160        170        180 
HREVCQFANA LKHLGVQKGD RVGIYMPMIP EAAIAMLACA RIGAPHTVVF GGFSAEALKD 

       190        200        210        220        230        240 
RLVDAQAKVV ITADGGWRKD AIVPLKAQVD QALEHGGAAC VENVLVVRRT GEPIPMQLGG 

       250        260        270        280        290        300 
RDHWWHELQQ LVSADCPAEP MDSEDMLFIL YTSGTTGKPK GVVHTTGGYN LYTHVTTKWI 

       310        320        330        340        350        360 
FDLQETDVYW CTADVGWITG HSYIVYGPLS NGATVLMYEG APRASNPGCF WDVIEKYQVN 

       370        380        390        400        410        420 
IFYTAPTAIR AFIKMGEHLP LARDLSSLRL LGTVGEPINP EAWMWYHRVI GGERCPIVDT 

       430        440        450        460        470        480 
WWQTETGGIM ITPLPGAIPT KPGSATLPFP GIQAEVVDLE GQPANSNDGG YLVVKQPWPG 

       490        500        510        520        530        540 
MMRTVYGDPD RFRRSYWEHI PPKDGHYVYF AGDGARQDED GYFWVMGRVD DVISVAGHRL 

       550        560        570        580        590        600 
GTMEIESALV SHPAVAEAAV VGKPDQLKGE EIVAFVTLEG THQPSEELKT ELKQHVVAEI 

       610        620        630        640        650 
GAIARPGEIR FADALPKTRS GKIMRRLLRT LASGSGITSD TSTLEDRSVL DKLREGS

« Hide

References

[1]"Complete sequence of chromosome Cyanothece sp. PCC 7425."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L., Sato H., Zhao L., Sherman L., Pakrasi H.B., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7425 / ATCC 29141.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001344 Genomic DNA. Translation: ACL46204.1.
RefSeqYP_002484565.1. NC_011884.1.

3D structure databases

ProteinModelPortalB8HUK2.
ModBaseSearch...

Protein-protein interaction databases

STRINGB8HUK2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7289832.
GenomeReviewsGene locus Cyan7425_3887 in contig CP001344_GR.
KEGGcyn:Cyan7425_3887.
PATRIC21568719. VBICyaSp30657_3856.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG547964.
OMAVISVSGH.
PhylomeDBB8HUK2.
ProtClustDBPRK00174.

Family and domain databases

HAMAPMF_01123. Ac_CoA_synth.
[Tree]
InterProIPR011904. Ac_CoA_lig.
IPR024597. Acyl-CoA_synth_DUF3448.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
KOK01895.
PANTHERPTHR24095:SF42. PTHR24095:SF42. 1 hit.
PfamPF00501. AMP-binding. 1 hit.
PF11930. DUF3448. 1 hit.
[Graphical view]
TIGRFAMsTIGR02188. Ac_CoA_lig_AcsA. 1 hit.
PROSITEPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8HUK2_CYAP4
AccessionPrimary (citable) accession number: B8HUK2
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info