ID   B8HUG4_CYAP4            Unreviewed;       583 AA.
AC   B8HUG4;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 69.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACL46166.1};
GN   OrderedLocusNames=Cyan7425_3848 {ECO:0000313|EMBL:ACL46166.1};
OS   Cyanothece sp. (strain PCC 7425 / ATCC 29141).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Gomontiellales; Cyanothecaceae;
OC   Cyanothece.
OX   NCBI_TaxID=395961 {ECO:0000313|EMBL:ACL46166.1};
RN   [1] {ECO:0000313|EMBL:ACL46166.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC 7425 {ECO:0000313|EMBL:ACL46166.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L.,
RA   Sato H., Zhao L., Sherman L., Pakrasi H., Richardson P.;
RT   "Complete sequence of chromosome Cyanothece sp. PCC 7425.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001344; ACL46166.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8HUG4; -.
DR   STRING; 395961.Cyan7425_3848; -.
DR   KEGG; cyn:Cyan7425_3848; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_50_3; -.
DR   OrthoDB; 9813903at2; -.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR33121:SF23; CYCLIC DI-GMP PHOSPHODIESTERASE PDEB; 1.
DR   PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00091; PAS; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          14..84
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          178..311
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          322..583
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   COILED          233..260
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   583 AA;  65611 MW;  2CF39AF031C6B5E3 CRC64;
     MILLPFSFPK DKQAQMFYAS LVQHCSDTIV VLAQDGKVQY VSPALTTVLG YRTGDWLGQP
     VLQHLHPEDI GLVKSHLSQL WQAPDTCLTW ELRCRHAEGT WMTLECTGKN LLYDPFLQGV
     VLYWRNINQR KATEETLRSV EARLSWQSQH DPLTGLLNRT AFESVLLKTL HQSLSEPQPH
     VLCYLDIDQF RIINDACGYR AGDELLCQVA SLVQNSLAVT DTFARLNSDS FGILLAQCSL
     EQARQLMERL RQKIQECRFI WQDKMFVTTV SIGLVEFSPA TPNLASLLNA AEAACYVAKE
     RGRNRCHNFQ SDDIELVQKR GAVQWLSYLN KALAENRFRL FFQTIRPLGK DAAPIDHYEV
     LLRLEDNGGQ LVSPAVFIGA AERFNLMPNI DRWVIKTLFA LIREQLIPQP DPAALSQEEQ
     HCFYAVNLSG ASINDDRLIE FLLEEFQTSG VPPAMICFEI TETVAISNLG KAAQLIRELK
     KLGCRFALDD FGSGMSSFGY LKNLPVDYLK IDGNFIRNII NDSIDLAMVR AIQQISQVMQ
     IETIAEFVEN QSILEAISDL GVNYAQGYAI APPAPLPALV TSH
//