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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Cyanothece sp. (strain PCC 7425 / ATCC 29141)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Cyan7425_3671
OrganismiCyanothece sp. (strain PCC 7425 / ATCC 29141)
Taxonomic identifieri395961 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeOscillatorialesCyanothecaceaeCyanothece
Proteomesi
  • UP000002511 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10001988921 – 585Arginine--tRNA ligaseAdd BLAST585

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi395961.Cyan7425_3671.

Structurei

3D structure databases

ProteinModelPortaliB8HSK8.
SMRiB8HSK8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi126 – 136"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
HOGENOMiHOG000247212.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG091H01RF.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

B8HSK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSPLDHLKT QLQRAMVAAY GETLSGADPL LVNASHPKFG DYQSNAPLPL
60 70 80 90 100
AKQLNQPPRT IASTIVDHLE VGEAWEPPTI AGPGFINFTL KTSYLASQLE
110 120 130 140 150
LRLTDPRLGI SAVKLPLRVV VDFSSPNIAK EMHVGHLRST IIGDCLARIL
160 170 180 190 200
EFLGHEVLRL NHVGDWGTQF GMLITYLREV CPEALTAPDA VDLGDLVAFY
210 220 230 240 250
RQAKQRFDSD PDFQAIARQE VVRLQSGEPD SLHAWQLLCA QSRREFEKIY
260 270 280 290 300
NLLDIKLTER GESFYNPLLP QVIQALDQTG LLVEDQGAKC VFLEGYTNKA
310 320 330 340 350
GDPQPLIVQK SDGGYIYATT DLAALRYRIE QDQADWIIYV TDAGQSTHFA
360 370 380 390 400
QVFQVAQRAG WIPNRIRLVH VPFGLVQGED GKKLKTRSGD TVRLQDLLDE
410 420 430 440 450
AIDRARNDLV SRLEAEGRQE TPEFIDHVAQ VVGIGAVKYA DLSQNRTSNY
460 470 480 490 500
VFSYDKMLSL QGNTAPYLIY AYVRVQGISR KGQIDLEQLT EQPTLSLQEE
510 520 530 540 550
EEKLLARHLL QLEDVLAQVT EDLLPNRLCQ YLFELSQKFN QFYDRCPILQ
560 570 580
AEEPLRNSRL GLAQLTARTL KLGLSLLGIQ VLERM
Length:585
Mass (Da):65,673
Last modified:March 3, 2009 - v1
Checksum:iA03581ECE8D0B38B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001344 Genomic DNA. Translation: ACL45991.1.
RefSeqiWP_012629049.1. NC_011884.1.

Genome annotation databases

EnsemblBacteriaiACL45991; ACL45991; Cyan7425_3671.
KEGGicyn:Cyan7425_3671.

Similar proteinsi

Entry informationi

Entry nameiSYR_CYAP4
AccessioniPrimary (citable) accession number: B8HSK8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: March 3, 2009
Last modified: November 22, 2017
This is version 51 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families