ID   B8HSJ9_CYAP4            Unreviewed;       842 AA.
AC   B8HSJ9;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 78.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACL45982.1};
GN   OrderedLocusNames=Cyan7425_3662 {ECO:0000313|EMBL:ACL45982.1};
OS   Cyanothece sp. (strain PCC 7425 / ATCC 29141).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Gomontiellales; Cyanothecaceae;
OC   Cyanothece.
OX   NCBI_TaxID=395961 {ECO:0000313|EMBL:ACL45982.1};
RN   [1] {ECO:0000313|EMBL:ACL45982.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC 7425 {ECO:0000313|EMBL:ACL45982.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L.,
RA   Sato H., Zhao L., Sherman L., Pakrasi H., Richardson P.;
RT   "Complete sequence of chromosome Cyanothece sp. PCC 7425.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001344; ACL45982.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8HSJ9; -.
DR   STRING; 395961.Cyan7425_3662; -.
DR   KEGG; cyn:Cyan7425_3662; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 425396at2; -.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 2.60.200.20; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000253; FHA_dom.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR008984; SMAD_FHA_dom_sf.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00498; FHA; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00240; FHA; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50006; FHA_DOMAIN; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
FT   DOMAIN          31..91
FT                   /note="FHA"
FT                   /evidence="ECO:0000259|PROSITE:PS50006"
FT   DOMAIN          268..340
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          344..396
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          429..562
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          571..827
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
SQ   SEQUENCE   842 AA;  96202 MW;  CC798B784077CCF1 CRC64;
     MNTKERQQVR HLLVIKDDGG RRTVPLEAAT YSLGRHASNS IVCHSPHVSR QHALLLRMTD
     PETGNFFFRI VDGNLQGKRS INGITVNGKR CASHNLKHGD LIVLGGDIKA RYHVISNVSD
     TGFRRYSEEV QGSSLPTTTD TGLGFQPITP SSKELSNLSE AALIRLSSFP EMNPNPILEV
     DLDGKITYLN PAAVQQFPEL KHNRSHPLLQ GLAELGQDEE QKYLVRELEV DGRIYEQTVH
     SISESHLVRC YMVDITQRKL TEQALRESEE RYAAAARGAN DGLWDWDLRT NQIYFSPRWK
     LILGWHEDEI GKNPEEWFDR IHHEDRERVK AELHYHLNGS KAHFESEHRL LHRDGSYRWV
     RSRGLALCDE DAIPYRIAGS LTDITAYRLA QEQILHDALH DALTGLPNRV LLLDRLAQAI
     HRGRRRSDYQ FAVLFLDLDR FKVINDSLGH MAGDRLLVEI AQRLQLCLRS EDTIARLGGD
     EFAILVEDIQ SVEAVLQLVE QLHAELNRPL SLDNQDIFTT ASIGIAFNSP QTEQPEELLR
     DADVAMYRAK SLGKNRHEIF SAGMRLEAIA QLQVETELRH ALERQELRVF YQPIIQLNEG
     TLYGFETLVR WEHPQRGLVL PLEFLPIAEE TGLIVPISWW VLQQACEQMQ AWQQQFPCSQ
     FLNISVNFTP QHFAQPSFLQ KLNRILAETG FPPHRLRLEV TENLFMKSTE TTIDILQELQ
     DWGIQIYLDD FGTGYSSLNY LHRFPINTLK IDRCFIGHLN SNGSHASIVQ AIMTLAHVLG
     LAVIAEGVET VEQLNQLCQL QCEFGQGYLF SLPLSQTQIA EYLAKNDLAW HNDYYSGNRI
     VR
//