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B8HRW7 (B8HRW7_CYAP4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 20. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
NADPH-dependent 7-cyano-7-deazaguanine reductase HAMAP MF_00818
EC=1.7.1.13 HAMAP MF_00818
Alternative name(s):
7-cyano-7-carbaguanine reductase HAMAP MF_00818
NADPH-dependent nitrile oxidoreductase HAMAP MF_00818
PreQ(0) reductase HAMAP MF_00818
Gene names
Name:queF HAMAP MF_00818
Ordered Locus Names:Cyan7425_0230
OrganismCyanothece sp. (strain PCC 7425 / ATCC 29141) [Complete proteome] [HAMAP] EMBL ACL42626.1
Taxonomic identifier395961 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length142 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) By similarity. HAMAP MF_00818

Catalytic activity

7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH. HAMAP MF_00818

Pathway

tRNA modification; tRNA-queuosine biosynthesis. HAMAP MF_00818

Subcellular location

Cytoplasm By similarity HAMAP MF_00818.

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. HAMAP MF_00818

Sequences

Sequence LengthMass (Da)Tools
B8HRW7 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 4D5C3CB98CDA7BD1

FASTA14216,133
        10         20         30         40         50         60 
MANLVESGQQ HDGTIAISTE LKYGERQIQE GQLITFPNPR PGRRYTIQIT LPEFTCKCPF 

        70         80         90        100        110        120 
SGYPDFATIH VSYIPDQRVV ELKAIKLYIN SYRDRYISHE ESVNQILDDL VTACDPLQIS 

       130        140 
VKGDFAPRGN VHTVIEVEHQ KA

« Hide

References

[1]"Complete sequence of chromosome Cyanothece sp. PCC 7425."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L., Sato H., Zhao L., Sherman L., Pakrasi H.B., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7425 / ATCC 29141.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001344 Genomic DNA. Translation: ACL42626.1.
RefSeqYP_002480987.1. NC_011884.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB8HRW7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7286136.
GenomeReviewsGene locus Cyan7425_0230 in contig CP001344_GR.
KEGGcyn:Cyan7425_0230.
PATRIC21561365. VBICyaSp30657_0220.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG294103.
OMAFRNAGIF.
PhylomeDBB8HRW7.

Family and domain databases

HAMAPMF_00818. QueF_type1.
[Tree]
InterProIPR016856. CN_OxRdtase_NADPH-dep_QueF.
IPR020602. GTP_CycHdrlase_I/CN_OxRdtase.
[Graphical view]
KOK09457.
PfamPF01227. GTP_cyclohydroI. 1 hit.
[Graphical view]
PIRSFPIRSF027377. Nitrile_oxidored_QueF. 1 hit.
TIGRFAMsTIGR03139. QueF-II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8HRW7_CYAP4
AccessionPrimary (citable) accession number: B8HRW7
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 20 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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