ID   B8HRI7_CYAP4            Unreviewed;       744 AA.
AC   B8HRI7;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 82.
DE   SubName: Full=Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) {ECO:0000313|EMBL:ACL45854.1};
GN   OrderedLocusNames=Cyan7425_3532 {ECO:0000313|EMBL:ACL45854.1};
OS   Cyanothece sp. (strain PCC 7425 / ATCC 29141).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Gomontiellales; Cyanothecaceae;
OC   Cyanothece.
OX   NCBI_TaxID=395961 {ECO:0000313|EMBL:ACL45854.1};
RN   [1] {ECO:0000313|EMBL:ACL45854.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC 7425 {ECO:0000313|EMBL:ACL45854.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L.,
RA   Sato H., Zhao L., Sherman L., Pakrasi H., Richardson P.;
RT   "Complete sequence of chromosome Cyanothece sp. PCC 7425.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001344; ACL45854.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8HRI7; -.
DR   STRING; 395961.Cyan7425_3532; -.
DR   KEGG; cyn:Cyan7425_3532; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_50_3; -.
DR   OrthoDB; 425396at2; -.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.50.2300; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SUPFAM; SSF52172; CheY-like; 1.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PROSITE-ProRule:PRU00169}.
FT   DOMAIN          17..133
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000259|PROSITE:PS50110"
FT   DOMAIN          311..444
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          453..713
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   REGION          707..744
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        727..744
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         70
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   744 AA;  83935 MW;  0B43E1A834768BC4 CRC64;
     MSSVPGLNGS TPAYPGLQIL LIADPTLAVL LQPLLAQSLL EPVQIVPIHP PEAALAQLHQ
     ADRSELILLD LALSENLDCL STLHQHAPHV PILVLLEESQ TGIAEQTLSA GATDYLFKSE
     LTPSLLRRSL RYILHGTEFQ QVEANLRQSE ARFFAAAEAS LDALFILQSY RHPEQNQIID
     FVCTDVNSRG EKLLGKPRQA ILGRFLSELL PVDSSKQLIQ KYTLVVETGQ VLEEELPVNI
     TPLPITWLHH QIVPLGDGIA ITARDISERK QKEAELHRQA FYDPLTELPN RTYFMNRLTK
     VLERAGRRQD FHYAVFFLDL DRFKVVNDSL GHLLGDEFLK AIARRLSSCL REEDMVARLG
     GDEFAILLEE LSNPDIVHRI AERLQRVLSA PFTLKQHELF TTASIGIALG TSYYEQPEAI
     LRDADIAMYQ AKTQGKARHI IFDQAMHTRA VKRWQLESDL RWAIERREFC LVYQPIVSIQ
     TERLIGFEAL VRWHHPQRGW ISPAEFISVA EETGLIIPLG HWVLWEGCRQ LRQWQSQFNL
     SPTAEPPLTV SVNLSSKQFC QPDLIHYIQQ VLQQTGMEGT CLKLELTESI LMENLSTATS
     LLVQLKELGI QLALDDFGTG YSSLSYLHRF PLDVLKIDRS FINGIEAETE NLEIVRTILS
     LARSLNLQVV AEGVETQAQL DHLQALQCGY AQGYLISRPL TPEKTEQFLQ EYLQSRGKDP
     ESSEQGQEEG SDQANDSPYP SRAA
//