ID   B8HNE5_CYAP4            Unreviewed;       877 AA.
AC   B8HNE5;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 76.
DE   SubName: Full=Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S) {ECO:0000313|EMBL:ACL47272.1};
GN   OrderedLocusNames=Cyan7425_4974 {ECO:0000313|EMBL:ACL47272.1};
OS   Cyanothece sp. (strain PCC 7425 / ATCC 29141).
OC   Bacteria; Cyanobacteriota; Cyanophyceae; Gomontiellales; Cyanothecaceae;
OC   Cyanothece.
OX   NCBI_TaxID=395961 {ECO:0000313|EMBL:ACL47272.1};
RN   [1] {ECO:0000313|EMBL:ACL47272.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=PCC 7425 {ECO:0000313|EMBL:ACL47272.1};
RG   US DOE Joint Genome Institute;
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T.,
RA   Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L.,
RA   Sato H., Zhao L., Sherman L., Pakrasi H., Richardson P.;
RT   "Complete sequence of chromosome Cyanothece sp. PCC 7425.";
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP001344; ACL47272.1; -; Genomic_DNA.
DR   AlphaFoldDB; B8HNE5; -.
DR   STRING; 395961.Cyan7425_4974; -.
DR   KEGG; cyn:Cyan7425_4974; -.
DR   eggNOG; COG5001; Bacteria.
DR   HOGENOM; CLU_000445_70_20_3; -.
DR   OrthoDB; 425396at2; -.
DR   CDD; cd01948; EAL; 1.
DR   CDD; cd01949; GGDEF; 1.
DR   CDD; cd00130; PAS; 2.
DR   Gene3D; 3.30.450.40; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.20.20.450; EAL domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 2.
DR   InterPro; IPR001633; EAL_dom.
DR   InterPro; IPR035919; EAL_sf.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR000160; GGDEF_dom.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013656; PAS_4.
DR   InterPro; IPR013655; PAS_fold_3.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   NCBIfam; TIGR00254; GGDEF; 1.
DR   NCBIfam; TIGR00229; sensory_box; 2.
DR   PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR   PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR   Pfam; PF00563; EAL; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF00990; GGDEF; 1.
DR   Pfam; PF08447; PAS_3; 1.
DR   Pfam; PF08448; PAS_4; 1.
DR   SMART; SM00052; EAL; 1.
DR   SMART; SM00065; GAF; 1.
DR   SMART; SM00267; GGDEF; 1.
DR   SMART; SM00086; PAC; 1.
DR   SMART; SM00091; PAS; 2.
DR   SUPFAM; SSF141868; EAL domain-like; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR   PROSITE; PS50883; EAL; 1.
DR   PROSITE; PS50887; GGDEF; 1.
DR   PROSITE; PS50113; PAC; 1.
DR   PROSITE; PS50112; PAS; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          192..262
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          309..381
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          385..437
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          470..603
FT                   /note="GGDEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50887"
FT   DOMAIN          612..868
FT                   /note="EAL"
FT                   /evidence="ECO:0000259|PROSITE:PS50883"
FT   COILED          175..202
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   877 AA;  100270 MW;  9118B1F24CF3E4CC CRC64;
     MDGAGAALGG SEGRLRRQNQ TLVDLSRRQK FYRGDFQAAL AEITQMAAST LEVERVGVFL
     YNADRNAIQC INLYERGPNR HSQGITLFAK DYPQYFQALE SERIIAAHDA GADPRTAEFQ
     PNYLIPLGLT SLLDAPIWVG GTMVGVVCHE HMGLKRYWLP EEQSFAGAIA DMVALALEAR
     DRQQAEAELQ KTNQQLRNIL ESLTSGFFSL NETAEFTYIN PQAEPLLQHS RAELLGHNLW
     QFFPALRDSS FFPYYQEAIT DQVTVKFEDY YPRLNRWLEI HICPFQTGVA VYLADISERK
     RTEAALMETK ERYALAIQGA NDGIWDWNLV NNEIYFSSRW KTILGYSESE VDNCLEEWFS
     RIHPQDLERV KLKLNLHQQG QSSHFEEEYR LRHKNGKYRW VLSRGIAVRN SEGKAYRMAG
     SLSDISEQRL AQEQLMHDAL HDPLTGLPNR TLFMDRLRQV IHHARRHRNY NFAVLFVDLD
     RFKVINDSLG HLAGDTLLIE LAHRFQIGLR PDDTVARLGG DEFVILLDDL LEVEESIRIA
     HRIQTLVQQP FIINGQTVFT SASIGIAPKD THHHKPEHYL RNADIAMYRA KAAGGSRHVL
     FTSVMHTSAL VRLQLETDLR QALERQELRL QYQPILCLNT DQIVGFEALV RWQHPRDGLI
     APGHFITVAE ETGLIVPIGE WVLQEACRQM QCWHTQFGQV LPLMVSVNLS SKQLSQPDLL
     QQVDRMLAET GLRPQQLKLE ITESMILDNT EVARQTLLKL KERQIQLSMD DFGTGYSSLN
     YLHRLPIDLL KIDRSFIHEM DSGEESRELV RAIISIAHSL KMQVIAEGIE TRSQLEQLHE
     LGCEFGQGYL FSTPLDPEPA ADFLQQAFLK QTNSPIS
//