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B8HM79 (B8HM79_CYAP4) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2 HAMAP MF_01840
Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase 2 HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF2 HAMAP MF_01840
Ordered Locus Names:Cyan7425_4781
OrganismCyanothece sp. (strain PCC 7425 / ATCC 29141) [Complete proteome] [HAMAP] EMBL ACL47086.1
Taxonomic identifier395961 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Chroococcales › Cyanothece

Protein attributes

Sequence length355 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
B8HM79 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 20833A3613AB9105

FASTA35541,739
        10         20         30         40         50         60 
MMVNAPPKPV TDVKAKALKE NILTPRFYTT DFEKTAQLDL SAQETELRAM LAEMQADYNR 

        70         80         90        100        110        120 
HHFVRDESFD ACWDQITGEA RQAFIDYLER SCVSEFSGFL LFKELSRKLK NRSPLLSEIF 

       130        140        150        160        170        180 
NLMARDEARH AGFLNKAMGD FGATMDLGHL TKNRVYTFFP IEWVLYTVYL SEKIGYWRYI 

       190        200        210        220        230        240 
IIFHHLQKHP ENQFYPLFKY FESWCQDENR HGDIFKALLR SQPQLWNTWQ SRLWSRFFLL 

       250        260        270        280        290        300 
TVFATHTLTV HERQGFYHLL GIDPTQFDTE VIRNTNETAA RAFPSILNTE HPQFFPRLQR 

       310        320        330        340        350 
CSDLNQKISA IDRSEQPKWL KALRKLPLKL AIGGHLLRIY FTPGIDAEAL RGTVR

« Hide

References

[1]"Complete sequence of chromosome Cyanothece sp. PCC 7425."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Sims D., Meineke L., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N. expand/collapse author list , Ovchinnikova G., Liberton M., Stoeckel J., Banerjee A., Singh A., Page L., Sato H., Zhao L., Sherman L., Pakrasi H.B., Richardson P.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 7425 / ATCC 29141.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001344 Genomic DNA. Translation: ACL47086.1.
RefSeqYP_002485447.1. NC_011884.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGB8HM79.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID7290735.
GenomeReviewsGene locus Cyan7425_4781 in contig CP001344_GR.
KEGGcyn:Cyan7425_4781.
PATRIC21570549. VBICyaSp30657_4763.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG284843.
OMANRHGDIF.
PhylomeDBB8HM79.
ProtClustDBPRK13654.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameB8HM79_CYAP4
AccessionPrimary (citable) accession number: B8HM79
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: December 14, 2011
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info