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B8HHA3

- B8HHA3_ARTCA

UniProt

B8HHA3 - B8HHA3_ARTCA

Protein
Submitted name:

2-hydroxy-3-oxopropionate reductase

Gene

Achl_3437

Organism
Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei171 – 1711UniRule annotation

    GO - Molecular functioni

    1. 2-hydroxy-3-oxopropionate reductase activity Source: InterPro
    2. 3-hydroxyisobutyrate dehydrogenase activity Source: InterPro
    3. NAD binding Source: InterPro
    4. phosphogluconate dehydrogenase (decarboxylating) activity Source: InterPro

    GO - Biological processi

    1. glyoxylate metabolic process Source: InterPro
    2. pentose-phosphate shunt Source: InterPro
    3. valine metabolic process Source: InterPro

    Enzyme and pathway databases

    BioCyciACHL452863:GH1A-3495-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    2-hydroxy-3-oxopropionate reductaseImported
    Gene namesi
    Ordered Locus Names:Achl_3437Imported
    OrganismiArthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)Imported
    Taxonomic identifieri452863 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
    ProteomesiUP000002505: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi452863.Achl_3437.

    Structurei

    3D structure databases

    ProteinModelPortaliB8HHA3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG2084.
    HOGENOMiHOG000219608.
    KOiK00042.
    OMAiELMNACA.
    OrthoDBiEOG6XDH0X.

    Family and domain databases

    Gene3Di1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    InterProiIPR002204. 3-OH-isobutyrate_DH-rel_CS.
    IPR008927. 6-PGluconate_DH_C-like.
    IPR006115. 6PGDH_NADP-bd.
    IPR013328. DH_multihelical.
    IPR015815. HIBADH-type.
    IPR016040. NAD(P)-bd_dom.
    IPR029154. NADP-bd.
    IPR006398. Tartro_sem_red.
    [Graphical view]
    PfamiPF14833. NAD_binding_11. 1 hit.
    PF03446. NAD_binding_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000103. HIBADH. 1 hit.
    SUPFAMiSSF48179. SSF48179. 1 hit.
    TIGRFAMsiTIGR01505. tartro_sem_red. 1 hit.
    PROSITEiPS00895. 3_HYDROXYISOBUT_DH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B8HHA3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSNVAVIGLG IMGLPMAINL VKAGHTVTGF NRSQDKIDKL VSEGGQGASS    50
    IADAVKDADV VITMVPDSPD VEGVVSGKDG VFANAKQGTL WIDASSIRPD 100
    VAKRLSEEAV AAGIRPLDAP VSGGEQGAID AVLSIMVGGD KTDFDAAQDV 150
    LNAVGKTIVH VGPSGSGQTV KAANQLIVAV NIEVLGEAIA FLEAYGVDTD 200
    AALKVLGGGL AGSKVLDQKG QKMLDRNFDP GFRLTLHHKD LGIVTSAARE 250
    ANVAVPLGAV VAQLVAATVN QGDGALDHSG LFKQVLQLSG RK 292
    Length:292
    Mass (Da):29,759
    Last modified:March 3, 2009 - v1
    Checksum:i9FEE427DB78F60B2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001341 Genomic DNA. Translation: ACL41394.1.
    RefSeqiYP_002489483.1. NC_011886.1.

    Genome annotation databases

    EnsemblBacteriaiACL41394; ACL41394; Achl_3437.
    GeneIDi7294918.
    KEGGiach:Achl_3437.
    PATRICi20993507. VBIArtChl38304_4116.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001341 Genomic DNA. Translation: ACL41394.1 .
    RefSeqi YP_002489483.1. NC_011886.1.

    3D structure databases

    ProteinModelPortali B8HHA3.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 452863.Achl_3437.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACL41394 ; ACL41394 ; Achl_3437 .
    GeneIDi 7294918.
    KEGGi ach:Achl_3437.
    PATRICi 20993507. VBIArtChl38304_4116.

    Phylogenomic databases

    eggNOGi COG2084.
    HOGENOMi HOG000219608.
    KOi K00042.
    OMAi ELMNACA.
    OrthoDBi EOG6XDH0X.

    Enzyme and pathway databases

    BioCyci ACHL452863:GH1A-3495-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1040.10. 1 hit.
    3.40.50.720. 1 hit.
    InterProi IPR002204. 3-OH-isobutyrate_DH-rel_CS.
    IPR008927. 6-PGluconate_DH_C-like.
    IPR006115. 6PGDH_NADP-bd.
    IPR013328. DH_multihelical.
    IPR015815. HIBADH-type.
    IPR016040. NAD(P)-bd_dom.
    IPR029154. NADP-bd.
    IPR006398. Tartro_sem_red.
    [Graphical view ]
    Pfami PF14833. NAD_binding_11. 1 hit.
    PF03446. NAD_binding_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000103. HIBADH. 1 hit.
    SUPFAMi SSF48179. SSF48179. 1 hit.
    TIGRFAMsi TIGR01505. tartro_sem_red. 1 hit.
    PROSITEi PS00895. 3_HYDROXYISOBUT_DH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequence of chromosome of Arthrobacter chlorophenolicus A6."
      US DOE Joint Genome Institute
      Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.
      Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360Imported.

    Entry informationi

    Entry nameiB8HHA3_ARTCA
    AccessioniPrimary (citable) accession number: B8HHA3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3