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B8HHA3

- B8HHA3_ARTCA

UniProt

B8HHA3 - B8HHA3_ARTCA

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Protein
Submitted name:

2-hydroxy-3-oxopropionate reductase

Gene
Achl_3437
Organism
Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei171 – 1711 By similarityUniRule annotation

GO - Molecular functioni

  1. 2-hydroxy-3-oxopropionate reductase activity Source: InterPro
  2. 3-hydroxyisobutyrate dehydrogenase activity Source: InterPro
  3. NAD binding Source: InterPro
  4. phosphogluconate dehydrogenase (decarboxylating) activity Source: InterPro

GO - Biological processi

  1. glyoxylate metabolic process Source: InterPro
  2. pentose-phosphate shunt Source: InterPro
  3. valine metabolic process Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciACHL452863:GH1A-3495-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
2-hydroxy-3-oxopropionate reductaseImported
Gene namesi
Ordered Locus Names:Achl_3437Imported
OrganismiArthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360)Imported
Taxonomic identifieri452863 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeMicrococcaceaeArthrobacter
ProteomesiUP000002505: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi452863.Achl_3437.

Structurei

3D structure databases

ProteinModelPortaliB8HHA3.

Family & Domainsi

Phylogenomic databases

eggNOGiCOG2084.
HOGENOMiHOG000219608.
KOiK00042.
OMAiELMNACA.
OrthoDBiEOG6XDH0X.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProiIPR002204. 3-OH-isobutyrate_DH-rel_CS.
IPR008927. 6-PGluconate_DH_C-like.
IPR006115. 6PGDH_NADP-bd.
IPR013328. DH_multihelical.
IPR015815. HIBADH-type.
IPR016040. NAD(P)-bd_dom.
IPR029154. NADP-bd.
IPR006398. Tartro_sem_red.
[Graphical view]
PfamiPF14833. NAD_binding_11. 1 hit.
PF03446. NAD_binding_2. 1 hit.
[Graphical view]
PIRSFiPIRSF000103. HIBADH. 1 hit.
SUPFAMiSSF48179. SSF48179. 1 hit.
TIGRFAMsiTIGR01505. tartro_sem_red. 1 hit.
PROSITEiPS00895. 3_HYDROXYISOBUT_DH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8HHA3-1 [UniParc]FASTAAdd to Basket

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MSNVAVIGLG IMGLPMAINL VKAGHTVTGF NRSQDKIDKL VSEGGQGASS    50
IADAVKDADV VITMVPDSPD VEGVVSGKDG VFANAKQGTL WIDASSIRPD 100
VAKRLSEEAV AAGIRPLDAP VSGGEQGAID AVLSIMVGGD KTDFDAAQDV 150
LNAVGKTIVH VGPSGSGQTV KAANQLIVAV NIEVLGEAIA FLEAYGVDTD 200
AALKVLGGGL AGSKVLDQKG QKMLDRNFDP GFRLTLHHKD LGIVTSAARE 250
ANVAVPLGAV VAQLVAATVN QGDGALDHSG LFKQVLQLSG RK 292
Length:292
Mass (Da):29,759
Last modified:March 3, 2009 - v1
Checksum:i9FEE427DB78F60B2
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001341 Genomic DNA. Translation: ACL41394.1.
RefSeqiYP_002489483.1. NC_011886.1.

Genome annotation databases

EnsemblBacteriaiACL41394; ACL41394; Achl_3437.
GeneIDi7294918.
KEGGiach:Achl_3437.
PATRICi20993507. VBIArtChl38304_4116.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001341 Genomic DNA. Translation: ACL41394.1 .
RefSeqi YP_002489483.1. NC_011886.1.

3D structure databases

ProteinModelPortali B8HHA3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 452863.Achl_3437.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACL41394 ; ACL41394 ; Achl_3437 .
GeneIDi 7294918.
KEGGi ach:Achl_3437.
PATRICi 20993507. VBIArtChl38304_4116.

Phylogenomic databases

eggNOGi COG2084.
HOGENOMi HOG000219608.
KOi K00042.
OMAi ELMNACA.
OrthoDBi EOG6XDH0X.

Enzyme and pathway databases

BioCyci ACHL452863:GH1A-3495-MONOMER.

Family and domain databases

Gene3Di 1.10.1040.10. 1 hit.
3.40.50.720. 1 hit.
InterProi IPR002204. 3-OH-isobutyrate_DH-rel_CS.
IPR008927. 6-PGluconate_DH_C-like.
IPR006115. 6PGDH_NADP-bd.
IPR013328. DH_multihelical.
IPR015815. HIBADH-type.
IPR016040. NAD(P)-bd_dom.
IPR029154. NADP-bd.
IPR006398. Tartro_sem_red.
[Graphical view ]
Pfami PF14833. NAD_binding_11. 1 hit.
PF03446. NAD_binding_2. 1 hit.
[Graphical view ]
PIRSFi PIRSF000103. HIBADH. 1 hit.
SUPFAMi SSF48179. SSF48179. 1 hit.
TIGRFAMsi TIGR01505. tartro_sem_red. 1 hit.
PROSITEi PS00895. 3_HYDROXYISOBUT_DH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequence of chromosome of Arthrobacter chlorophenolicus A6."
    US DOE Joint Genome Institute
    Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P.
    Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Entry informationi

Entry nameiB8HHA3_ARTCA
AccessioniPrimary (citable) accession number: B8HHA3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: September 3, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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