B8HGD0 (B8HGD0_ARTCA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Argininosuccinate lyase HAMAP MF_00006
Short name=ASAL HAMAP MF_00006
EC=4.3.2.1 HAMAP MF_00006

Alternative name(s):
Arginosuccinase HAMAP MF_00006

Gene names

Name:	argH HAMAP MF_00006
Ordered Locus Names:	Achl_1504

Organism

Arthrobacter chlorophenolicus (strain A6 / ATCC 700700 / DSM 12829 / JCM 12360) [Complete proteome] [HAMAP]

Taxonomic identifier

452863 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Micrococcaceae › Arthrobacter

Protein attributes

Sequence length	480 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2-(N(omega)-L-arginino)succinate = fumarate + L-arginine. HAMAP MF_00006
Pathway	Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3. HAMAP MF_00006
Subcellular location	Cytoplasm By similarity HAMAP MF_00006.
Sequence similarities	Belongs to the lyase 1 family. Argininosuccinate lyase subfamily. HAMAP MF_00006

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Arginine biosynthesis HAMAP MF_00006
Cellular component	Cytoplasm HAMAP MF_00006
Molecular function	Lyase HAMAP MF_00006 EMBL ACL39492.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine biosynthetic process via ornithine Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	argininosuccinate lyase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8HGD0 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 4F3C7D4D1C5B0265	FASTA	480	51,444
	10 20 30 40 50 60 MVEPVETQKT EATNAGALWG GRFAGGPADA LAALSKSTHF DWRLARYDIA GSKAHARVLH 70 80 90 100 110 120 KAGLLDDAEL EGMLAALTQL DEDVASGAYL PAESDEDVHG SLERGLIERA GAQLGGKLRA 130 140 150 160 170 180 GRSRNDQVAT LGRMFLRDHA RIIARGVLAT IDALVEQAKA HQGVAMPGRT HLQHAQPVLL 190 200 210 220 230 240 SHHLLAHAWP LLRDVQRLQD WDKRAGVSPY GSGALAGSSL GLDPEAVAAD LGFFSAAHNS 250 260 270 280 290 300 IDGTAARDVF AEFAWVCSMI GVDLSRISEE VIFWATKEFS FVTLHDSYST GSSIMPQKKN 310 320 330 340 350 360 PDVAELARGK AGRLIGNLTG LLATLKGLPL AYNRDLQEDK EPVFDAADTL ELLLPAVSGM 370 380 390 400 410 420 IATLTFNRER MESLAPQGFA LATDIAEWLV RQGVPFREAH ELSGAAVKQA ESRGVELWDL 430 440 450 460 470 480 TDDEYAAISE HLTPEVRTVL STEGSLNSRN SQGGTAPAAV ERQLAALESE LAGVREYAGQ

References

[1]

"Complete sequence of chromosome of Arthrobacter chlorophenolicus A6." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Goltsman E., Clum A., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Jansson J., Richardson P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: A6 / ATCC 700700 / DSM 12829 / JCM 12360.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001341 Genomic DNA. Translation: ACL39492.1.
RefSeq	YP_002487581.1. NC_011886.1.
3D structure databases
ProteinModelPortal	B8HGD0.
ModBase	Search...
Protein-protein interaction databases
STRING	B8HGD0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	7292953.
GenomeReviews	Gene locus Achl_1504 in contig CP001341_GR.
KEGG	ach:Achl_1504.
PATRIC	20989551. VBIArtChl38304_2170.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG539632.
OMA	MPGRTHL.
ProtClustDB	PRK00855.
Family and domain databases
HAMAP	MF_00006. Arg_succ_lyase. [Tree]
InterPro	IPR009049. Argininosuccinate_lyase. IPR003031. D_crystallin. IPR000362. Fumarate_lyase. IPR020557. Fumarate_lyase_CS. IPR008948. L-Aspartase-like. IPR022761. Lyase1_N. [Graphical view]
KO	K01755.
PANTHER	PTHR11444:SF3. argH. 1 hit.
Pfam	PF00206. Lyase_1. 1 hit. [Graphical view]
PRINTS	PR00145. ARGSUCLYASE. PR00149. FUMRATELYASE.
SUPFAM	SSF48557. L-Aspartase-like. 1 hit.
TIGRFAMs	TIGR00838. ArgH. 1 hit.
PROSITE	PS00163. FUMARATE_LYASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8HGD0_ARTCA

Accession

Primary (citable) accession number: B8HGD0

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	December 14, 2011
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)